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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease melanoma, malignant
Symptom C0494165|liver metastases
Sentences 7
PubMedID- 24597767 Investigating genes involved in significant gos and pathways, 297 genes in common were found that may affect the liver metastases of uveal melanoma patients.
PubMedID- 22707951 In one study, liver metastases of uveal melanomas produced approximately twice as much mif as primary uveal melanoma cells (repp et al., 2000).
PubMedID- 25521594 Tace seems to be a tolerable regimen that confers an improvement in the survival of uveal melanoma patients with liver metastases.
PubMedID- 20838706 Surgical metastasectomy in ajcc stage iv m1c melanoma patients with gastrointestinal and liver metastases.
PubMedID- 24653816 Meir et al20 compared gene expression in liver metastases of uveal melanoma with that of primary uveal melanoma and reported that metastatic melanoma has a distinct gene expression profile.
PubMedID- 26082068 The aim of this study was to determine the presence of exosomes, and their rna content, from isolated hepatic perfusion from uveal melanoma patients with liver metastases.
PubMedID- 24899684 We also analyzed the expression of ddx43 in liver metastases of patients with uveal melanoma by rt-pcr, and found a significant overexpression of ddx43 in patients who did not benefit from selumetinib therapy.

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