eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | melanoma, malignant |
| Symptom | C0042900|vitiligo |
| Sentences | 14 |
| PubMedID- 25834362 | The presence of vitiligo in melanoma has been reported, and kit is thought to be partly responsible for the dysfunction and loss of melanocytes observed in vitiligo. |
| PubMedID- 21909283 | Waardenburg syndromes), differentiation (albinism), survival (vitiligo) or control of proliferation (melanoma) 6. |
| PubMedID- 25605840 | Purpose: vitiligo-like depigmentation in patients with melanoma may be associated with more favorable clinical outcome. |
| PubMedID- 23136900 | Objectives: this retrospective, comparative cohort survey was designed to assess lifetime prevalences of melanoma and nmsc in patients with vitiligo compared with nonvitiligo controls. |
| PubMedID- 25242557 | Background: genetic findings suggesting a lower susceptibility to melanoma in patients with vitiligo are supported by recent clinical studies. |
| PubMedID- 21911918 | A small study of 11 patients reported that survival was slightly prolonged in metastatic melanoma patients with vitiligo, but concluded that data supporting a ‘direct relationship between the two conditions’ was still lacking . |
| PubMedID- 22561518 | The associated region contains 20 genes, notably including mc1r, encoding the melanocortin receptor, a regulator of melanogenesis and minor vitiligo autoantigen, associated with malignant melanoma and with skin and hair color20. |
| PubMedID- 25702668 | Association of vitiligo and response in patients with metastatic malignant melanoma on temozolomide. |
| PubMedID- 22908963 | Regarding the expression levels of dppiv (as cd26) on lymphocytes, no significant differences in the percentages of cd26+ lymphocytes (figure 2b), and in the values for mean fluorescence intensity (mfi) of cd26 expression on lymphocytes (figure 2c) were found between the melanoma patients, people with vitiligo and healthy control subjects. |
| PubMedID- 23887251 | Cutaneous vitiligo following management of uveal melanoma in 6 patients. |
| PubMedID- 21794122 | The incidence of vitiligo in patients with melanoma, although rare, is estimated to be seven to ten-fold higher than the general population . |
| PubMedID- 20498710 | Successful melanoma immunotherapy can lead to treatment-related vitiligo-like leukoderma as an autoimmune side-effect , which is considered an encouraging prognostic sign , . |
| PubMedID- 24366614 | Additionally, association of vitiligo with immunotherapy of melanoma employing activated cytotoxic t cells specific for shared tumor antigens and melanosomal proteins further supports the autoimmune etiology of vitiligo(mehrotra et al., 2012; sakai et al., 1997; yee et al., 2000). |
| PubMedID- 24082190 | The occurrence of vitiligo like lesions in patients with metastatic melanoma in comparison has a better prognosis. |
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