eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | melanoma, malignant |
| Symptom | C0027962|melanocytic nevi |
| Sentences | 8 |
| PubMedID- 24433184 | Semiquantitative evaluation of this expression revealed downregulated expression of rpe65 in malignant melanoma compared with benign melanocytic nevi (p < 0.001). |
| PubMedID- 25692084 | In one study, bolognia et al concluded that “a small percentage of ‘small dark dots’ within melanocytic nevi are due to melanoma”, finding 3 (5%) of 59 such nevi to be melanoma 3. |
| PubMedID- 23739702 | The risk of cutaneous melanoma in melanocytic nevi. |
| PubMedID- 22550586 | The magnitude of the shift reflects the local stiffness of the tissue, which has shown promising results when comparing benign melanocytic nevi with melanoma . |
| PubMedID- 24672253 | There have been reports of histological atypia (pseudomelanoma) in patients with melanocytic nevi that were treated by co2 lasers as well as lasers for hair removal.33 racial differences probably also need to be taken into consideration, as in asians, the incidence of melanoma has been reported to be between 0.2 and 2.2 per 100,000, much lower than among whites.34 furthermore, the most common sites for the development of melanoma among people with skin of color are areas not directly exposed to the sun, such as palmar, plantar, subungual, and mucosal surfaces.34 this may account for the liberal use of lasers for the treatment of melanocytic nevi in asian countries on the facial skin. |
| PubMedID- 20086181 | We aimed to estimate the population attributable fraction (paf) for melanoma associated with melanocytic nevi using relative risk estimates derived from a systematic review and meta-analysis. |
| PubMedID- 21876460 | Altered expression of stat3 mrna, pstat3, and socs3 protein was observed in melanoma specimens, compared with benign melanocytic nevi. |
| PubMedID- 22906024 | Nevertheless, further studies are needed to validate the functional role of 14-3-3 proteins in melanotumorigenesis through the proteomic comparison of different malignant melanoma patients with giant congenital melanocytic nevi. |
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