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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease marfan syndrome
Symptom C1866956|aortic root dilation
Sentences 5
PubMedID- 23321647 Losartan added to beta-blockade therapy for aortic root dilation in marfan syndrome: a randomized, open-label pilot study.
PubMedID- 20006934 Losartan may prevent aortic root dilation in marfan syndrome.
PubMedID- 25001203 Fluid dynamics of aortic root dilation in marfan syndrome.
PubMedID- 21985537 Role of angiotensin receptor blockers for management of aortic root dilation associated with marfan syndrome.
PubMedID- 20452541 These animal data, combined with recent retrospective trials showing markedly reduced rates of aortic root dilation in patients with marfan syndrome treated with angiotensin receptor blockers, suggest a powerful role for angiotensin receptor blockers in the treatment of aortic aneurysms.

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