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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease malaria
Symptom C0022346|jaundice
Sentences 7
PubMedID- 24020374 A significant increase in mda levels on d1 in p. vivax malaria (with and without jaundice) group was observed compared to the control group.
PubMedID- 24636003 An ultrastructural study reported an association between high prbc load in the livers of malaria patients with jaundice, hepatomegaly and liver enzyme elevation6.
PubMedID- 22606519 Causes of jaundice in malaria direct causes: malarial hepatitis, intravascular hemolysis of parasitized rbc, and septicemic hepatitis.indirect causes: microangiopathic hemolysis associated with dic, g6pd-related hemolysis, and anti-malarial-drug induction.unrelated causes: coexisting acute viral hepatitis.
PubMedID- 19817958 Results: seventy-four severe pf malaria patients with jaundice were enrolled.
PubMedID- 24490093 jaundice in malaria may be explained by severe haemolysis (indirect bilirubine predominance) or liver cholestasis (direct bilirubine predominance).
PubMedID- 26466783 Hyperbilirubinaemia, which is also known as jaundice, is often associated with malaria infection.
PubMedID- 23431634 Conclusions: jaundice in patients with malaria may be considered as a warning sign associated with liver and kidney dysfunction.

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