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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease malaria
Symptom C0002871|anemia
Sentences 55
PubMedID- 25250072 Peripheral smear showed microcytic hypo chromic anemia with no malaria parasite.
PubMedID- 21075280 Other factors, including response to anemia, and the influence of infection with malaria and other environmental influences, may be important.
PubMedID- 21529383 Known and possible causes of hemolytic anemia in association with malaria or antiparasitic therapy include blackwater fever, artemisinin-induced reticulocytopenia, direct hemolytic effects of the drug, and drug-induced immune hemolytic anemia.
PubMedID- 22094132 Whereas epo ameliorates hemolytic anemia in malaria or trypanosomiasis and improves the course of autoimmune diseases such as inflammatory bowel disease or autoimmune encephalomyelitis, it deleteriously inhibits macrophage functions in salmonella infection in animal models.
PubMedID- 25604792 malaria induces anemia through cd8+ t cell-dependent parasite clearance and erythrocyte removal in the spleen.
PubMedID- 23620856 Objective: to assess the prevalence of anemia in children with urinary schistosomiasis, malaria and concurrent infections by the two diseases.
PubMedID- 21479575 malaria infection leads to anemia in humans which generally occurs during the chronic phase of the infection.
PubMedID- 24520208 The majority of recipients in emerging countries are younger and more likely to be women and children.53 transfusion most frequently occurs because of acute blood loss from injury and obstetric hemorrhage, which are best treated with fresh whole blood, and for childhood anemia due to malaria.54 the who recommends whole blood for malaria,55 in which metabolic acidosis and hypovolemia56 may be ameliorated by the fresh plasma portion.
PubMedID- 22287859 The demand for blood transfusion is high in sub-saharan africa because of the high prevalence of anemia especially due to malaria and pregnancy-related complications.
PubMedID- 25928774 We also did not observe a protective effect between baseline anemia and the risk of developing malaria as has been suggested elsewhere .
PubMedID- 23490427 Additional strategies to improve sp coverage may reduce the lbw and maternal anemia associated with malaria in pregnancy.
PubMedID- 25285308 anemia in malaria is believed to occur due to hemolysis of parasitized and nonparasitized rbcs, peripheral removal/sequestration of rbcs, and ineffective erythropoiesis (due to high circulating tissue necrotic factor (tnfα)) .
PubMedID- 24450283 Severe anemia accounts for half of all malarial deaths in african children and women, co-infection with malaria and intestinal worms has been shown to result in greater anemia.
PubMedID- 25960095 Thirteen studies found that malaria infection was associated with anemia or lowered hemoglobin; in these studies, malaria accounted for more of the variation in anemia than nutritional status.
PubMedID- 23113116 However, various studies have demonstrated that p. vivax malaria was associated with mild anemia and increased risk of low birth weight, which may be more pronounced in multigravidae than in primigravidae (25).
PubMedID- 23382166 Overall 16.8% of anemia cases were associated with malaria, 8.3% with iron deficiency, and 6.1% with inflammation.
PubMedID- 25889703 anemia associated with asymptomatic malaria among pregnant women in the rural surroundings of arba minch town, south ethiopia.
PubMedID- 25807235 Moreover, excessive hemolysis of parasitized rbcs in malaria infection may lead to anemia 9.
PubMedID- 24237997 Independent of hiv, maternal malaria is associated with anemia and maternal mortality .
PubMedID- 24358185 Severe anemia associated with malaria was defined as hgb<6 g/dl and a positive smear.
PubMedID- 24517107 In the pediatric ward, anemia due to malaria was the main indication for transfusion, followed by sickle cell vaso-occlusive crisis.
PubMedID- 21072315 The aim of this study is to assess the prevalence of anemia in malaria parasitemic women during first antenatal booking visit in a tertiary hospital in a low resource setting.
PubMedID- 24587473 Our findings are also consistent with research suggesting that in the context of low socio-demographic status, even light infections such as hookworm and malaria may be associated with anemia , ; however, further research is needed to address these relationships.
PubMedID- 23109959 malaria was strongly associated with anemia in this study.
PubMedID- 26465787 Severe hemolytic anemia in malaria is caused by the destruction of host rbcs following plasmodium parasite growth and, to a greater extent, by the elimination of uninfected rbcs .
PubMedID- 23945350 anemia in malaria is multifactorial and mainly due to haemolysis and dyserythropoiesis .
PubMedID- 22131906 The question of whether the synesthesia gene(s) may have a “hidden agenda” like the sickle cell anemia gene has with malaria resistance, and whether that agenda may be “creativity and metaphor”, was first raised by ramachandran and hubbard .
PubMedID- 22826498 Twenty-one percent, 15%, 12%, 11% and 7% of anemia were attributable to malnutrition, malaria, iron, folic acid deficiencies, and helminth infestations, respectively.
PubMedID- 22506087 anemia, a hallmark of both vl and malaria, negatively correlated with the co-occurrence of malaria in vl patients.
PubMedID- 25884992 Hiv increases the degree to which malaria is associated with severe anemia and low birth weight beyond the effect of hiv itself on these outcomes.
PubMedID- 23573367 Moreover, malaria induced anemia was studied in comparison with anemia induced by hemorrhage and hemolysis.
PubMedID- 25567973 For example, the characteristic anemia associated with malaria infection is driven by a combination of destruction of infected rbcs by parasites, as well as haemolysis (ritter et al.
PubMedID- 20196168 Common causes of anemia in malaria-infected children, such as increased parasitemia or reduced erythropoiesis, did not account for worsening anemia in the hiv-1(+)/pf(+) group nor did carriage of sickle cell trait or g6pd deficiency.
PubMedID- 24550911 Of all the plasmodium species infecting humans, p. falciparum is the most virulent and its pathology is characterized by severe anemia or the development of cerebral malaria, generally leading to death if left untreated (3).
PubMedID- 24218409 There were certain outlier costs, such as in 2005, when cerebral malaria with anemia and malaria with severe anemia cost on average more than severe malaria.
PubMedID- 24834053 Makes several key predictions that support a role for erythropoiesis in driving the protection from malaria associated with iron deficiency anemia and increased risk associated with iron supplementation.
PubMedID- 24575278 Pthophysiologic mechanisms of anemia in malaria is such as direct invasion of red cells, anemia of chronic disease hypersplenism, hemophagocytic syndrome and erythrophagocytosis, dyserythropoirsis, immune haemolysis and cytokine deregulation anemia of chronic disorder is characterized by moderate to mild normocytic, normochromic anemia along with microcytic hypochromic cells.
PubMedID- 21738863 Both clinical and asymptomatic malaria have been associated with anemia of inflammation.
PubMedID- 22096530 Furthermore, in malaria, alleles associated with sickle-cell anemia, thalassemias, and glucose-6-phosphate dehydrogenase deficiency confer protective effects, whereas polymorphisms in the tnf-α gene have been linked to increased risk of cerebral malaria (cm) .
PubMedID- 24358031 Following childhood, a second peak in the fraction of anemia attributable to malaria was apparent for all species between the ages of approximately 15 and 25 years (figure 6).
PubMedID- 23950937 Comorbidities included both communicable and non-communicable disorders: anemia, hypertensive disorders of pregnancy (hdp), sepsis, malaria, hiv/aids, and other (convulsions; coagulopathy and pulmonary edema; and history of dizziness, weakness and fainting spells).
PubMedID- 25548419 An imported case of severe falciparum malaria with prolonged hemolytic anemia clinically mimicking a coinfection with babesiosis.
PubMedID- 25221716 1 malaria induced anemia is much more common in younger children and may require blood transfusion with high mortality rates.
PubMedID- 20859503 In asplenic, elderly, or immunocompromised patients a severe malaria-like illness with hemolytic anemia and renal failure can occur.
PubMedID- 22888709 anemia was significantly associated with asymptomatic malaria infection among hiv patients on haart with an odd ratio of 16.47 (95%: ci: 0.919, 295.5; p = 0.021).
PubMedID- 20386613 Several mechanisms seem to contribute to anemia during malaria, with pronounced differences in different patient populations and animal models.
PubMedID- 20505829 malaria was strongly associated with anemia which is consistent with previous reports , .
PubMedID- 22752514 Acidosis in severe malaria has been associated with severe anemia and respiratory distress or deep breathing and is an established strong predictor of mortality in adult as well as pediatric severe malaria .
PubMedID- 24050302 In bolivia, the paf of moderate-to-severe anemia associated with p. vivax malaria was 3.5%, and the paf for low birthweight was 6.1% for p. vivax.
PubMedID- 22072995 malaria leads to severe anemia and cycles of fever as the parasite takes hold.

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