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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease juvenile myoclonic epilepsy
Symptom C0014550|myoclonic seizures
Sentences 6
PubMedID- 23986742 The oral form has food and drug administration (fda) indications for adjunctive therapy in the treatment of partial onset epilepsy ages 1 month or more, myoclonic seizures associated with juvenile myoclonic epilepsy starting with the age of 12 and primary generalized tonic-clonic seizures in people 6 years and older.
PubMedID- 21395360 Worldwide, levetiracetam is most commonly approved as adjunctive treatment of partial onset seizures with or without secondary generalization; other approved indications include monotherapy treatment of partial onset seizures with or without secondary generalization, and adjunctive treatment of myoclonic seizures associated with juvenile myoclonic epilepsy and primary generalized tonic-clonic (gtc) seizures associated with idiopathic generalized epilepsy.
PubMedID- 21936590 Worldwide, levetiracetam is most commonly approved as adjunctive treatment of partial-onset seizures with or without secondary generalization; other approved indications include monotherapy treatment of partial-onset seizures with or without secondary generalization, and adjunctive treatment of myoclonic seizures associated with juvenile myoclonic epilepsy and primary generalized tonic-clonic (gtc) seizures associated with idiopathic generalized epilepsy.
PubMedID- 25667841 Levetiracetam (s)-alpha-ethyl-2-oxo-1-pyrrolidine acetamide (lev) is a second generation anticonvulsant approved by the european medicines agency (ema) and/or the u.s. food and drug administration (fda) for the following: 1) monotherapy treatment of partial seizures, with or without secondary generalization (ema); 2) adjunctive treatment of partial seizures, with or without secondary generalization (fda/ema); 3) adjunctive treatment of myoclonic seizures associated with juvenile myoclonic epilepsy (fda/ema); and 4) adjunctive treatment of primary generalized tonic–clonic seizures associated with idiopathic generalized epilepsy (fda/ema) .
PubMedID- 24009559 At present, lev is a worldwide commonly used second generation aed, approved as adjunctive and monotherapy treatment of partial-onset seizures with or without secondary generalization, and adjunctive treatment of myoclonic seizures associated with juvenile myoclonic epilepsy and primary generalized tonic-clonic seizures associated with idiopathic generalized epilepsy (lyseng-williamson, 2011).
PubMedID- 24027645 Levetiracetam is an established second-generation antiepileptic drug that is approved as a treatment of partial seizures; other indications include adjunctive treatment of myoclonic seizures associated with juvenile myoclonic epilepsy and primary generalized tonic-clonic seizures associated with generalized epilepsy.

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