eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | immunoglobulin a deficiency |
| Symptom | C0021311|infections |
| Sentences | 4 |
| PubMedID- 24935667 | In both humans and dogs, iga deficiency (igad) is associated with recurrent infections of mucosal sites and immune-mediated diseases. |
| PubMedID- 23836815 | Thus, iga(-/-) mice are highly susceptible to primary pulmonary lvs infections not only because of iga deficiency but also because of reduced ifn-gamma responses. |
| PubMedID- 22240193 | Aims: to describe the relationship of selective iga deficiency with infections, allergic diseases, autoimmune disorders and tumours. |
| PubMedID- 25875365 | It seems that, the increased frequency of infections associated with iga deficiency could therefore precipitate autoimmune disease such as systemic lupus erythematus, graves' disease, celiac, recurrent parotiditis, inflammatory bowel syndrome, crohn's disease, juvenile idiopathic arthritis and type 1 diabetes . |
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