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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hypopituitarism
Symptom C0271801|central hypothyroidism
Sentences 4
PubMedID- 26576309 In our case, hypopituitarism presenting with central hypothyroidism and secondary adrenal insufficiency was thought to be associated with the sclerotic dysplasia of the sella turcica and anterior pituitary injury.
PubMedID- 22574251 An endocrine work-up conducted at this time revealed hypopituitarism with central hypothyroidism (free t4 level, 0.1 ng/dl; thyroid-stimulating hormone level, 1.71 miu/l), diabetes insipidus (urine specific gravity, 1.005; sodium level, 141 mmol/l), and growth hormone deficiency, as determined by an igf-1 level of <25 ng/ml (reference range 97–352 ng/ml).
PubMedID- 21603211 hypopituitarism manifested with central hypothyroidism and hypoadrenalism such that her medications at presentation included thyroid supplementation (37.5 mcg or 10 mcg/kg/day) and hydrocortisone (8 mg/m2/day).
PubMedID- 26413367 Laboratory investigation revealed a partial hypopituitarism with a slight central hypothyroidism without need for substitution.

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