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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease hyperthermia
Symptom C0024530|malaria
Sentences 91
PubMedID- 22035466 This can, for instance, be done through discussion platforms for clinicians about alternative management of fever with a negative malaria test.
PubMedID- 21453493 fever was also associated with malaria infection in univariate analysis (p = 0.003), but this association was not significant anymore in multivariate analysis (aor = 1.6; p = 0.069).
PubMedID- 21645402 Uncomplicated malaria generally presents with fever, malaise, and other non-specific symptoms; distinguishing malaria from other febrile illnesses based on clinical presentation is challenging .
PubMedID- 20609211 In the dry season (table 3), only in patients with over 4,000 parasites/μl was a considerable proportion of fever cases attributable to malaria (af = 24% for parasite density between 4,001 and 40,000, and 86% for parasite density > 40,000).
PubMedID- 24555424 To reduce the fever associated with malaria especially in young children, the bark diospyros scabra is boiled and the patient is bathed in the concoction.
PubMedID- 24596021 "comment: some of the authors are employed by the trial sponsors but all authors had access to data and assumed responsibility for reporting accuracy.ringwald 1996methodstrial design: randomized, parallel group, active controlled trialduration of trial: recruitment: april 1994 to may 1995participantsnumber randomized: 96age: 15 to 64 yearsgender: 42 males; 54 femalesinclusion criteria:acute falciparum malaria with fever within the past 24 hrs or a temperature above 37.5 °c at the time of consultationover 5000 asexual parasites/µlno signs and symptoms of severe and complicated malariano recent self-medicationexclusion criteria:pregnant womenmixed infectionsinterventionsintervention1.
PubMedID- 25902716 Between july and december 2013 a further seven individuals, who had been screened at least once during the acd programme and tested negative for malaria, presented with fever to the same dgh and were diagnosed with p. vivax malaria.
PubMedID- 20339579 A total of 18 health workers out of 25 (72%) confirmed that they prescribed treatment in the absence of laboratory diagnosis arguing that fever is strongly associated with malaria in an endemic area, and such an attitude allows to exclude for the patient thick and thin blood film cost which is officially charged 0.76 usd.
PubMedID- 23940677 malaria specific symptoms consisted of having a fever with either a headache or chills in the prior two weeks.
PubMedID- 25150266 The first patient of plasmodium falciparum malaria presented with fever and altered sensorium; mri of the brain suggested cerebral venous thrombosis.
PubMedID- 21740570 The study considered patients at least two years old suffering from acute, uncomplicated plasmodium falciparum malaria with fever (axillary temperature ≥37.5°c) and a parasitaemia of between 1,000 and 100,000 trophozoites/μl in senegal and 2,000 to 200,000 trophozoites/μl in cameroon and ivory coast.
PubMedID- 22434978 All the 454 (100%) respondents had information about malaria and 394 (86.8%) of the respondents mentioned fever as a symptom of malaria.
PubMedID- 21824389 But there are malaria cases with high fever who can take oral medication, or cases with fever and diarrhea not thought to be due to malaria.
PubMedID- 21787434 Differentiating fever attributed to malaria from other fever by aetiology.
PubMedID- 20624312 Presumptive treatment of fever with anti-malarials is widely practised to reduce malaria-attributable morbidity and mortality especially at lower level health facilities where microscopy is not readily available .
PubMedID- 25604792 Uncomplicated malaria consists of cycles of high fever and chills.
PubMedID- 21499691 The rupture of the schizont and release of merozoites give rise to the so-called malaria paroxysms with spiking fever and rigors.
PubMedID- 22230355 Proactive case detection (acd), or household malaria screening of those with fever by surveillance workers, was conducted in bhutan in the 1960s and 1970s, but has not been employed since that time.
PubMedID- 21961019 While this situation might have justified the presumptive treatment of fever with antimalarials (i.e., treating all febrile episodes suspected of malaria with a full therapeutic dose of antimalarials), such practice might have led to a reduced susceptibility of parasites to the commonly used antimalarial drugs in these settings.
PubMedID- 24180319 In view of this, travel history as well as past history of acquiring malaria in patients with fever must be recorded in detail to assist in the diagnosis and management of travellers’ malaria and severe malaria.
PubMedID- 24626194 For decades, a high importance was given to malaria as a cause of fever, which has led to an overestimation of its burden and at the same time an underestimation of other diseases.
PubMedID- 23356837 The availability of rapid diagnostic tests (rdts) allows rural health workers to reliably rule out malaria in fever patients.
PubMedID- 21054891 The results of this study suggest that it is worthwhile to perform blood films on hospitalized neonates with fever in malaria endemic regions since though it is rare, congenital and neonatal malaria does occur.
PubMedID- 20727214 Assigning malaria as a cause of fever in the absence of laboratory diagnosis is based on clinical experience but also on an understanding of the underlying epidemiology of the disease.
PubMedID- 24722554 With growing awareness of the over-diagnosis and misclassification of malaria as the cause of fever illnesses in the tropics, including africa, there is increased interest in the role of non-malarial causes of fever, such as c. burnetii.
PubMedID- 25141554 Awareness and practices of 101 consecutive clinically suspected malaria cases (presenting with fever) attending medical opd in satyawadi raja harishchandra hospital, narela in north west district of delhi regarding malaria were assessed using a 37 item pre-tested, semi-structured, semi-open ended, and investigator administered questionnaire.
PubMedID- 23977655 The classic presentation of malaria with paroxysms of fever is seen only in 50-70% of the patients.
PubMedID- 23217163 In tropical africa, the differentiation of malaria from other causes of fever in the absence of microscopy is notoriously difficult.
PubMedID- 25802432 However, with the roll back malaria initiative, the causes of fever in africa may change.
PubMedID- 20409342 *adjusted for age, ethnicity, wealth, clinical malaria (in the case of anaemia), current fever (for parasitaemia), district, and whether or not the child had slept under an itn the previous night.
PubMedID- 20925921 Houses where at least one member had experienced symptoms of malaria including fever and/or convulsions in the previous four weeks were included in the study.
PubMedID- 21631932 Tumour necrosis factor (tnf) is an important mediator of fever in malaria , and experimental data suggest that both tnf and fever have anti-parasitic properties .
PubMedID- 24415936 One child had symptomatic malaria (parasitemia with a fever requiring treatment) at the time of the blood draw, and 17 (22%) had blood smears demonstrating parasitemia.
PubMedID- 25588165 A multivariate regression model has been developed that utilized raman spectra of 20 malaria-infected, 10 non-malarial with fever, 10 healthy, and 6 dengue-infected samples to optically predict the malaria infection.
PubMedID- 24885909 For most of the population (89%), fever with other classical malaria symptoms was an indication to visit a local clinic with a microscopist or other health officer.
PubMedID- 24279720 In zambia, for example, health workers diagnosed fewer than 30% of fever patients with a malaria rdt/blood slide following the introduction of a treatment protocol similar to that employed in png, even when rdts/microscopy were available 8.
PubMedID- 22846165 Children with symptoms and signs of malaria including: fever, chills, malaise, headache, vomiting or other systemic complaints were included in this study after informed consent was obtained from the parents/adolescent themselves.
PubMedID- 22952642 Since 2007, testing is recommended only for fever cases with malaria-related history and symptoms - body aches, joint pain, headache, nausea, vomiting, or diarrhea.
PubMedID- 22047131 Thirdly, this will encourage health care providers to search for alternative causes of fever in malaria-negative patients, and particularly those that can become dangerous or even fatal if treatment is delayed .
PubMedID- 25584420 In a similar study in kenya, majority of women associated headache (70%) and fever (68.8%) with malaria .
PubMedID- 20169070 This could be the sweating due to fever associated with the malaria infection might attract the additional mosquitoes bites.
PubMedID- 21179571 It has been argued that active surveillance is more likely than passive surveillance to misdiagnose asymptomatic parasitaemia with a coincident, non-malaria cause of fever as a true malaria case, leading to over-estimation of burden of malaria .
PubMedID- 21057136 Studies were included that had patients suspected of having acute malaria (usually because of fever) and compared the presence or absence of clinical findings with blood smear confirmation.
PubMedID- 20659316 Despite the significant association of fever with malaria parasitaemia, this was of limited usefulness due to the low parasitaemia rate.
PubMedID- 20370920 The presence of fever in conjunction with a positive malaria smear correlated with parasite density in p. falciparum infections (f1,34 = 8.48, p = 0.006), but not in p. vivax infections (f1,77 = 1.89, p = 0.174).
PubMedID- 23029433 Considering all fever episodes associated with malaria parasites as clinical attacks overestimated p.
PubMedID- 21268544 This work evaluated the clinical and parasitic status of malaria as a cause of fever among patients admitted to the military fever hospitals.
PubMedID- 22554149 Background: although early diagnosis and prompt treatment is an important strategy for control of malaria, using fever to initiate presumptive treatment with expensive artemisinin combination therapy is a major challenge; particularly in areas with declining burden of malaria.
PubMedID- 23273022 If non-malarial causes of fever were the aetiology of some of these presentations, malaria incidence may have been overestimated in this cohort.
PubMedID- 23350022 The study included randomly selected cases of acute malaria which presented with fever for within a week caused either by plasmodium falciparum (pf), vivax (pv) or dual infection (pv+pf) that were retrieved from the archives of the laboratory.

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