eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hyperaldosteronism |
| Symptom | C0020538|hypertension |
| Sentences | 11 |
| PubMedID- 26273475 | We describe a young male patient with longstanding hypertension, who was diagnosed with primary hyperaldosteronism and treated by an attempted retroperitoneoscopic total unilateral adrenalectomy for a left-sided presumed aldosterone-secreting adenoma. |
| PubMedID- 21785705 | Prevalence of resistant hypertension in patients with primary hyperaldosteronism is 17–22%, higher than in the general hypertensive population. |
| PubMedID- 23153688 | We suspected the presence of hyperaldosteronism because of resistant hypertension (33.1%), hypokalemia (38.2%), and hypertensive crises (12.7%). |
| PubMedID- 20119882 | Primary aldosteronism is the most common form of secondary hypertension and patients with hyperaldosteronism are more prone to premature cardiovascular complications compared to essential hypertensives. |
| PubMedID- 21902953 | Two years later, the patient developed signs of recurrent hyperaldosteronism with hypertension refractory to antihypertensive medication, hypokalemia as well as elevated aldosterone level and suppressed serum renin. |
| PubMedID- 23102075 | The main determinants of surgical cure or control of hypertension in patients with primary hyperaldosteronism were duration of hypertension, number of antihypertensive medications, preoperative response to spironolactone, the presence of adenoma, and cyp11b2 (344 c/t) genotype. |
| PubMedID- 23479921 | The patient had hypertension associated with hyperaldosteronism and chronic interstitial nephritis. |
| PubMedID- 22547442 | hyperaldosteronism combined with hypertension favored the macrophage infiltration (cd68(+) cells) in heart, and enhanced the mrna level of monocyte chemoattractant protein 1, osteopontin, and galectin 3. |
| PubMedID- 25546991 | Difficulty in diagnosis of primary hyperaldosteronism as the cause of resistant hypertension and severe hypokalemia--case report. |
| PubMedID- 23209837 | Studies demonstrated that hyperaldosteronism is associated with hypertension, cardiovascular fibrosis, and electrolyte disturbances, including hypomagnesemia. |
| PubMedID- 23087856 | Some varieties of low renin hypertension especially those associated with hyperaldosteronism are associated with increased cardiovascular morbidity and mortality. |
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