eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hepatitis c |
| Symptom | C0009450|infection |
| Sentences | 461 |
| PubMedID- 23584069 | These effects may be mediated by three general mechanisms:increasing hiv-related mortality directly (e.g., by exacerbating immunosuppression);enhancing the toxicity of art (e.g., by exacerbating the toxic effects of arvs on the liver i.e., hepatotoxicity); andincreasing mortality unrelated to hiv or art (e.g., by accelerating liver damage from concurrent infection with the hepatitis c virus hcv or increasing the likelihood of traumatic injury). |
| PubMedID- 24156952 | In asymptomatic naive patients, cart is recommended if the cd4(+) lymphocyte count is <500cells/mul; if the cd4(+) lymphocyte count is >500cells/mul, cart can be delayed, although it may be considered in patients with liver cirrhosis, chronic infection due to hepatitis c virus, high cardiovascular risk, plasma viral load (pvl) >10(5)copies/ml, cd4(+) lymphocyte percentage <14%, cognitive impairment, and age >55 years. |
| PubMedID- 21183794 | Chronic infection with hepatitis c virus (hcv) is a major public health problem, with nearly 170 million infected individuals worldwide. |
| PubMedID- 21316532 | Background: cirrhosis developing during chronic infection with the hepatitis c virus (hcv) poses a risk of anticipated liver-related death, therefore representing a dominant indication to anti-hcv therapy. |
| PubMedID- 24211330 | End stage liver disease caused by chronic infection with the hepatitis c virus (hcv) is a leading indication for liver transplantation, yet outcomes are poor since the liver graft is rapidly re-infected by hcv. |
| PubMedID- 25610012 | Changes in transaminase levels did not differ by medication, and as expected, baseline infection with hepatitis c or b was the only significant predictor for elevation of transaminase levels. |
| PubMedID- 22068541 | infection with hepatitis c virus (hcv) is a major medical problem with over 170 million people infected worldwide. |
| PubMedID- 21211210 | The influence of human immunodeficiency virus co-infection with hepatitis c virus and hepatitis b virus on the efficacy of high active anti-retroviral therapy. |
| PubMedID- 22593164 | Expression of microrna mir-122 facilitates an efficient replication in nonhepatic cells upon infection with hepatitis c virus. |
| PubMedID- 24695489 | The egyptian population has a heavy burden of liver disease, mostly due to chronic infection with hepatitis c virus . |
| PubMedID- 21627721 | The site-specific excess deaths suggest the role of tobacco, alcohol, and infection with hepatitis c and human papillomavirus. |
| PubMedID- 20136983 | Occult hepatitis b virus infection in patients with chronic hepatitis c: an actor behind the scene or just a bystander. |
| PubMedID- 20622998 | A clear aggregated environmental risk factor for the development of cirrhosis attributable to alcohol consumption is infection with hepatitis c virus (hcv). |
| PubMedID- 25643666 | infection with hepatitis c virus (hcv) is the major cause of chronic liver disease that occurs after renal transplantation. |
| PubMedID- 21167208 | infection with the hepatitis c virus represents a global public health threat given that an estimated 170 million individuals are chronically infected and thus at risk for cirrhosis and hepatocellular carcinoma. |
| PubMedID- 25708172 | infection with hepatitis c virus (hcv) leads to a wide spectrum of clinical manifestations. |
| PubMedID- 20843308 | The present work adds to the knowledge on the prevalence and the virological expression of hbv infection in patients with chronic hepatitis c providing data from a region where co-infection with the two viruses is not yet well documented. |
| PubMedID- 20941333 | Great britain and ireland: the working group “blood born viruses and anaesthesia” of the association of anaesthetists of great britain and ireland has critically examined the common practice at that time of leaving breathing systems for all patients on one operation list after a debatable cross-infection with hepatitis c had occurred in the mid-nineties . |
| PubMedID- 24694258 | Coinfection with hepatitis c virus (hcv) worsens neurological functioning regardless of hiv infection status. |
| PubMedID- PMC3882569 | Chronic infection with hepatitis c virus (hcv) induces a chronic stimulation of b lymphocytes and, in some cases, this stimulation can lead to chronic lymphoid disorders like non-hodgkin lymphoma. |
| PubMedID- 22579035 | There have been no reports, however, of primary infection with the hepatitis c virus during treatment with a biologic agent. |
| PubMedID- 22406819 | Association of cytomegalovirus infection and disease with recurrent hepatitis c after liver transplantation. |
| PubMedID- 23701894 | Background: infection with hepatitis c virus (hcv) is associated with high morbidity and increased mortality but many patients avoid initiation of treatment or report challenges with treatment completion. |
| PubMedID- 24886477 | In japan, an infection rate of the hepatitis c is high, and there are many hepatocellular carcinoma (hcc) cases. |
| PubMedID- 25182146 | Cirrhosis due to metabolic syndrome, alcohol consumption, viral infection with hepatitis c virus (hcv) is also involved in its development. |
| PubMedID- 26147900 | These findings suggest that the host immune response plays an important role in seronegative occult hcv infection in comparison with chronic hepatitis c. |
| PubMedID- 24719731 | Background: chronic infection with hepatitis c virus (hcv) is increasingly recognized as a major global health problem. |
| PubMedID- 24461160 | Background: infection with the hepatitis c virus (hcv) has been considered a major cause of mortality, morbidity and resource utilisation in the us. |
| PubMedID- 21181310 | It is also important for the treating physician to look for co-infection with hepatitis c. co-infection with hepatitis c is relatively sparing of hypercholesterolemia or lipodystrophy but also poses potential problems of increased vulnerability to hepatic damage from hepatotoxic drugs. |
| PubMedID- 25705875 | infection with hepatitis c virus (hcv) is a worldwide public health problem, a major cause of liver cirrhosis and hepatocellular carcinoma, and has been considered the leading indication for liver transplantation 1. |
| PubMedID- 24640721 | The effectiveness of methylglucamine acridonacetates in integrated treatment of chronic hepatitis c, tuberculosis with hiv infection background, chronic brucellosis, arboviral diseases, including west nile fever, as well as influenza and acute respiratory infections are shown. |
| PubMedID- 24147097 | Concurrent infection with hepatitis c virus (hcv) and hepatitis b virus (hbv) was not uncommon in china. |
| PubMedID- 23087749 | Regarding the clinical consequences of occult hbv infection in patients with chronic hepatitis c, studies have indicated the negative influence of cryptogenic hbv infection on histologic activity and severity of liver disease and hcc, possibly by integration with the host genome or synthesis of pro-oncogenic proteins by free intrahepatic hbv genomes (34, 36, 37, 38). |
| PubMedID- 21870716 | Chronic infection with hepatitis c virus is nowadays responsible for many cases of liver disease. |
| PubMedID- 24651679 | Objective: infection with hepatitis c virus (hcv) or human immunodeficiency virus (hiv) may be associated with atherosclerosis and vascular disease. |
| PubMedID- 25408375 | Chronic infection with hepatitis c virus (hcv) is caused by an inadequate immune response. |
| PubMedID- 25331321 | Exclusion criteria: 1) co-infection with hepatitis c virus (hcv); 2) positive serum anti-hbc igm; 3) hbeag positive patients; 4) patients who had received prior antiviral therapy for hbv; 5) patients having stigmata of liver cell failure e.g., ascites, encephalopathy; 6) pregnancy or breast feeding; 7) patients with organ transplants; and 8) patients receiving steroids and/or immunosuppressive drugs. |
| PubMedID- 20616580 | Persistent infection with hepatitis c virus (hcv) is a major risk toward development of hepatocellular carcinoma. |
| PubMedID- 24767674 | Egypt, with nearly 90 million habitants, has the highest infection rate of hepatitis c worldwide, with a prevalence of 10% according to the official records of the egyptian ministry of health and population (5). |
| PubMedID- 22546735 | Occult infection with hepatitis c virus: friend or foe. |
| PubMedID- 24269995 | Among them, 230 patients had a persistent infection with hepatitis c virus (hcv) with 129 patients affected by a chronic hepatitis and 101 patients by a hepatocellular carcinoma (hcc). |
| PubMedID- 23504650 | People detained in prisons and other closed settings are at elevated risk of infection with hepatitis c virus (hcv). |
| PubMedID- 23217121 | All students tested negative for infection with hepatitis c virus and human immunodeficiency virus. |
| PubMedID- 22212930 | Persistent infection with hepatitis c virus (hcv) is a major risk for the development of hepatocellular carcinoma (hcc). |
| PubMedID- 24799891 | infection with hepatitis c virus (hcv) is a global health problem and it infects at least 170 million people worldwide with an estimated prevalence of 3 to 4 million newly acquired infections per year 1. |
| PubMedID- 21994696 | Chronic infection with hepatitis c virus (hcv) is associated with significant liver disease and is therefore an important public health problem. |
| PubMedID- 23380966 | Hepatitis-b virus infection predicts mortality of hiv and hepatitis c virus coinfected patients. |
| PubMedID- 24173174 | Theresults demonstrated that the co-infected were younger (33.5 years x 45.3), less likelyto have rural activities either at the time of the diagnosis (27.5% x 59.4%) orpreviously (64.3% x 95.5%) and that they had a higher rate of associated hepaticdisease, particularly infection with hepatitis c virus (15.5% x 3.8%). |
| PubMedID- 22574212 | Exclusion criteria were as follows: 1) lsm failure (no valid shots; n = 0), 2) invalid lsm defined as an interquartile range (iqr) to median value ratio (iqr/m) >0.3, success rate <60%, or <10 valid measurements; n = 6 , 3) a history of hepatic decompensation or antiviral treatment (n = 0), 4) co-infection with hepatitis c, hepatitis d, or hiv (n = 1), 5) heavy alcohol consumption (>30 g/day for >5 years; n = 4), 6) right-sided heart failure, ascites, or pregnancy (n = 0), 7) f0–2 fibrosis stage on lb (n = 20), 8) low viral load (<2,000 iu/ml; n = 7), 9) lb specimen shorter than 15 mm (n = 9), and 10) follow-up loss (n = 3) (figure s1). |
| PubMedID- 24069039 | Chronic infection with hepatitis c virus (hcv) is increasingly recognized as a major global health problem (1, 2). |