eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | fibrous dysplasia |
| Symptom | C0030193|pain |
| Sentences | 4 |
| PubMedID- 25212962 | Literature review: there are only a few reports in the literature that describe the locally aggressive variant of fibrous dysplasia that presents with pain and progressive swelling clinically and with cortical destruction and soft tissue extension on imaging which suggest malignancy. |
| PubMedID- 21383639 | The symptoms of osteofibrous dysplasia include painless enlargement and bowing of the tibia and pain occurring in the presence of pathological fracture. |
| PubMedID- 21342594 | In the case of fibrous dysplasia associated with pain, or imminent fracture, a prophylactic surgical intervention is indicated. |
| PubMedID- 22640953 | Another way to develop new therapies to treat pain associated with fibrous dysplasia is to understand the unique populations of nerve fibers that innervate bone and the mechanisms by which these nerve fibers signal skeletal pain. |
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