eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | fibromyalgia |
| Symptom | C0030193|pain |
| Sentences | 73 |
| PubMedID- 26482422 | Authors' conclusions: the evidence available indicates that milnacipran 100 mg or 200 mg is effective for a minority in the treatment of pain due to fibromyalgia, providing moderate levels of pain relief (at least 30%) to about 40% of participants, compared with about 30% with placebo. |
| PubMedID- 23564998 | Relationship between sleep and pain in adolescents with juvenile primary fibromyalgia syndrome. |
| PubMedID- 24624294 | fibromyalgia is often associated with regional pain syndromes characterized by central sensitization such as low back pain, osteoarthritis, migraine, temporomandibular pain, irritable bowel syndrome, and interstitial cystitis . |
| PubMedID- 25599302 | The results suggest that tdcs has the potential to induce statistically significant pain relief in patients with fibromyalgia, with no serious adverse effects, but small effect sizes indicate that the results are unlikely to reflect clinically important changes. |
| PubMedID- 20488620 | The provisional questionnaire was tested in a prospective multicenter study of 162 patients with chronic pain due to fibromyalgia (according to acr criteria) (n=92) compared with a group of patients with chronic diffuse pain due to other rheumatic conditions, including rheumatoid arthritis (n=32), ankylosing spondylitis (n=25) and osteoarthritis (n=13). |
| PubMedID- 24022710 | Prevalence of the fibromyalgia phenotype in patients with spine pain presenting to a tertiary care pain clinic and the potential treatment implications. |
| PubMedID- 24792477 | fibromyalgia typically presents with spontaneous body pain with no apparent cause and is considered pathophysiologically to be a functional disorder of somatosensory processing. |
| PubMedID- 21568193 | Objective: this study analyzes the role of a number of cognitive-affective dimensions in the experience and coping of pain in patients with fibromyalgia (fm). |
| PubMedID- 21085031 | Purpose: the purpose of this study was to examine the influence of a preferred- versus a prescribed-intensity exercise session on pain in women with fibromyalgia (fm). |
| PubMedID- 21036635 | Objective: the purpose of the study was to evaluate the efficacy and safety of dolasetron for symptomatic relief of pain associated with fibromyalgia (fm). |
| PubMedID- 22842297 | The role of illness perception and emotions on quality of life in fibromyalgia compared with other chronic pain conditions. |
| PubMedID- 24671502 | fibromyalgia may present with widespread pain and tenderness, fatigue, anxiety, and depression and is associated with a low pain threshold. |
| PubMedID- 22935170 | Objectives: to assess the extent of coexistence of inflammatory back pain (ibp) with fibromyalgia (fm) features in patients with spondyloarthritis (spa), and to assess the degree of overlap of fm tender points (tep) and enthesitis sites (es) in patients with spa. |
| PubMedID- 21426373 | Overall there is evidence that cannabinoids are safe and modestly effective in neuropathic pain with preliminary evidence of efficacy in fibromyalgia and rheumatoid arthritis. |
| PubMedID- 24084413 | Evidence-based effective prm interventions include exercise and multicomponent treatment including a psychotherapeutic intervention such as cognitive behavioural therapy (cbt) in addition to exercise, the latter based on strong evidence for reducing pain and improving quality of life in fibromyalgia syndrome (fms). |
| PubMedID- 23006430 | Cerebral blood flow dynamics during pain processing in patients with fibromyalgia syndrome. |
| PubMedID- 25329143 | Sex differences in psychological response to pain in patients with fibromyalgia syndrome. |
| PubMedID- 24286267 | Williams and colleagues found that pain levels of eight fibromyalgia patients in washington, dc on the day after the attack did not differ significantly from pain levels before the attack5. |
| PubMedID- 23002409 | A study utilizing a “mini-mmpi”, the mmpi-2, reported that psychological disturbance in fibromyalgia changed with pain intensity and found neurotic symptoms common in all groups . |
| PubMedID- 25979860 | Altered cortical processing of observed pain in patients with fibromyalgia syndrome. |
| PubMedID- 20377879 | Sleep interference was assessed using the sleep interference item from the mbpi-sf, a 0-10 nrs that asks "how, during the past 24 hours, pain due to your fibromyalgia has interfered with your sleep?" |
| PubMedID- 20921842 | Randomized trials have documented significant analgesic effects for managing chronic pain associated with fibromyalgia and diabetic peripheral neuropathic pain. |
| PubMedID- 22419330 | Authors' conclusions: the evidence available indicates that milnacipran 100 mg or 200 mg is effective for a minority in the treatment of pain due to fibromyalgia, providing moderate levels of pain relief (at least 30%) to about 40% of participants, compared with about 30% with placebo. |
| PubMedID- 26106555 | Previous findings by our group have also shown increased dmn connectivity to the insula in chronic pain patients diagnosed with fibromyalgia (napadow et al., 2010): greater insula to dmn connectivity was associated with more clinical pain. |
| PubMedID- 24273710 | We performed a separate whole brain gray matter voxel-wise analysis in all fibromyalgia patients with pain duration as a predictor. |
| PubMedID- 21918649 | More recently, pilot trials of low-dose naltrexone hydrochloride (ldn), which is a pharmaceutical similar to naloxone, have recently gained increasing recognition for treating chronic pain associated with fibromyalgia, multiple sclerosis, and crohn's disease . |
| PubMedID- 24693945 | Several studies have demonstrated that whole body vibration exercise can reduce pain for women with fibromyalgia syndrome , young patients with musculoskeletal pain , and elderly patients with knee osteoarthritis . |
| PubMedID- 23070670 | pain uncertainty in patients with fibromyalgia, yoga practitioners, and healthy volunteers. |
| PubMedID- 24839443 | Several studies have reported a positive relationship between number of tps and self-reported somatosensory symptoms of neuropathic pain in patients with cwp and fibromyalgia , as well as a positive correlation between neuropathic pain symptoms and pressure pain thresholds measured by cpa . |
| PubMedID- 21542893 | A recent study of 68 fibromyalgia patients with myofascial pain syndromes and 56 fibromyalgia patients with regional joint pain showed that peripheral trigger point injections and hydroelectrophoresis ameliorate fibromyalgia pain and increase pain thresholds at sites distant from the therapeutic interventions , providing further evidence that painful peripheral stimuli contribute to the perpetuation of central augmentation. |
| PubMedID- 21197318 | For example, improved blood flow may be a mechanism through which exercise improves pain and quality of life among fibromyalgia patients.27 to date, however, the cvac process has not been tested in fibromyalgia populations, although 5 of 10 participants in this study had a diagnosis of fibromyalgia. |
| PubMedID- 21386950 | Other treatment options available for treating chronic pain due to fibromyalgia or diabetic neuropathy involve the use of many different classes of pharmacologic agents, including tricyclic antidepressants, selective serotonin reuptake inhibitors and norepinephrine reuptake inhibitors, anticonvulsants, and opiates.39 anticonvulsants, such as gabapentin and pregabalin, are effective at reducing pain, making them reasonable first-line options for the patient suffering from chronic neuropathic pain. |
| PubMedID- 23031395 | However, higher levels of pain within fibromyalgia were associated with shorter telomere length (p = .039). |
| PubMedID- 21283147 | Persistent and disabling pain is the hallmark of osteoarthritis, rheumatoid arthritis, fibromyalgia, and various other rheumatologic conditions. |
| PubMedID- 21926186 | In particular, if tenderness is due to factors beyond inflammation (eg, higher pain perception of the patient, fibromyalgia, etc), the das28 score may not correlate with ramris measures of inflammation depending on the relative contribution of the tender joint count to the das28 score. |
| PubMedID- 22591551 | Conclusions: the biodanza aquatic exercises improve pain and quality of life in fibromyalgia patients. |
| PubMedID- 22135739 | In addition to pain, many patients with fibromyalgia complain of problems with memory and concentration, often referred to as “fibrofog” . |
| PubMedID- 24790444 | Sleep quality was poor in fibromyalgia patients and in patients with low-back pain, although sleep quality was worse in fibromyalgia patients (p<0.05). |
| PubMedID- 19729492 | Various investigations have centered on the relationship of fibromyalgia with pain, depression, anxiety and quality of life. |
| PubMedID- 22204615 | Previous research has shown that transcranial direct current stimulation relieves pain in patients with fibromyalgia, chronic neuropathic pain and chronic pelvic pain. |
| PubMedID- 20816025 | In experimental settings, fibromyalgia is associated with lowered pain thresholds (hyperalgesia) and deficient pain inhibition. |
| PubMedID- 22046206 | 9 showed that 20 minutes of daily direct anodal stimulation over the primary motor cortex for 5 days is effective to decrease pain in patients with fibromyalgia as compared with sham and to active prefrontal tdcs. |
| PubMedID- 25786046 | Objectives: emerging evidence associates fibromyalgia (fm) with pain system dysfunction. |
| PubMedID- 21868622 | Cerebral blood flow alterations in pain-processing regions of patients with fibromyalgia using perfusion mr imaging. |
| PubMedID- 25887888 | In spite of being relatively common, it is still rarely diagnosed because of a pleomorphic presentation varying from mild cases of dryness, fatigue, and pain confounding with fibromyalgia (fm) to severe systemic cases similar to rheumatoid arthritis (ra) and systemic lupus erythematosus (sle). |
| PubMedID- 23603031 | Our findings demonstrate that 5-ht(2c) receptors play a critical role in muscular hyperalgesia in rim rats and suggest that 5-ht(2c) receptor agonists have therapeutic potential for treating chronic pain in patients with fibromyalgia although clinical extrapolation remains to be a future challenge. |
| PubMedID- 23142918 | Specifically, this review focused on literature that examined productive work with individuals who have chronic pain due to fibromyalgia, breast cancer, multiple sclerosis, and human immunodeficiency virus. |
| PubMedID- 19473857 | Depression, anxiety, health-related quality of life and pain in patients with chronic fibromyalgia and neuropathic pain. |
| PubMedID- 19935069 | The notion of central nervous system hypersensitivity affecting widespread pain in patients with fibromyalgia syndrome is the result of a reduction in neurophysiologic inhibition of perception of noxious stimuli that is provoked by disordered sleep. |
| PubMedID- 22110944 | A very interesting finding is that 5-ht3 receptor antagonists are effective in fibromyalgia patients with a primary pain phenotype (without depression) but not in fibromyalgia patients with depression . |
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