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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease endophthalmitis
Symptom C0021311|infections
Sentences 3
PubMedID- 20390032 For intravitreal antibiotic application in bacterial infections, as with exogenous endophthalmitis treatment, vancomycin (1.0 mg/0.1 ml) for gram-positive coverage or in combination with the β-lactam antibiotic ceftazidime (2.25 mg/0.1 ml) or amikacin (400 μg/0.1 ml) is recommended for gram-negative coverage.
PubMedID- 21750627 Other manifestations include skin lesions in the setting of disseminated infection (such as fusarium species, acremonium species, aspergillus species, and zygomycetes), ocular involvement (endophthalmitis with blindness), osteoarticular infections, and uncommonly, gastrointestinal involvement.
PubMedID- 25486541 Among patients with hematogenous infections, odds of endogenous endophthalmitis were higher for children and middle-aged patients, and for patients with endocarditis, bacterial meningitis, lymphoma/leukemia, hiv/aids, internal organ abscess, diabetes with ophthalmic manifestations, skin cellulitis/abscess, pyogenic arthritis, tuberculosis, longer hospital stays, and/or icu/nicu admission.

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