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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease eclampsia
Symptom C0036572|seizures
Sentences 8
PubMedID- 21151680 Use of magnesium sulfate to prevent eclamptic seizures in women with mild pre-eclampsia is controversial, and the acog practice bulletin stops short of recommending it in this case.34,4 a statistical decision analysis comparing the use versus nonuse of magnesium sulfate in women with mild pre-eclampsia found that nonuse reduced fetal mortality by 15% and avoided maternal toxicity, while maternal mortality was increased two-fold and fetal neurologic complications increased with use of magnesium.
PubMedID- 23963425 The american college of obstetricians and gynecologists and the society for maternal-fetal medicine continue to support the short-term (usually less than 48 hours) use of magnesium sulfate in obstetric care for appropriate conditions and for appropriate durations of treatment, which includes the prevention and treatment of seizures in women with preeclampsia or eclampsia, fetal neuroprotection before anticipated early preterm (less than 32 weeks of gestation) delivery, and short-term prolongation of pregnancy (up to 48 hours) to allow for the administration of antenatal corticosteroids in pregnant women between 24 weeks of gestation and 34 weeks of gestation who are at risk of preterm delivery within 7 days.
PubMedID- 23941365 In this case, evidence for a pres were: postpartum eclampsia with encephalopathy and seizures, occipital localization of the lesions on ct-scan and reversibility of the disorders .
PubMedID- 22873658 Studies have shown that the drug significantly lowers the possibility of seizures in women with severe pre-eclampsia or eclampsia, prevents progression from severe pre-eclampsia to eclampsia and generally lowers maternal mortality .
PubMedID- 24791084 The patient with seizures due to eclampsia should be treated with magnesium sulfate 2 g iv and continuous infusion of 2 g/h in 5% dextrose.
PubMedID- 26069818 seizures in eclampsia were distinguished from other types of seizures primarily by the absence of previous history of seizures before pregnancy .
PubMedID- 21384403 Intravenous infusion of magnesium sulfate prevents seizures in patients with eclampsia and brain edema after traumatic brain injury.
PubMedID- 21547090 There is significant evidence which supports the use of magnesium sulphate to prevent seizures in women with severe preeclampsia and eclampsia .

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