eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | duodenal ulcer |
| Symptom | C0850666|h. pylori infection |
| Sentences | 7 |
| PubMedID- 23833377 | the vast majority of primary duodenal ulcers are associated with h. pylori infection of the gastric antral mucosa. |
| PubMedID- 21687723 | H. pylori is the etiological agent of peptic ulcer disease, 75% of gastric ulcers and 90% of duodenal ulcers are attributed to h. pylori infection (ernst and gold, 2000), as well as two distinct forms of gastric cancer: mucosa-associated lymphoid tissue (malt) lymphoma and adenocarcinoma (parsonnet et al., 1991, 1994; talley et al., 1991; blaser, 1998). |
| PubMedID- 24010097 | Therefore, duodenal ulcers are highly associated with h. pylori infection regardless of prevalence. |
| PubMedID- 24975170 | It is therefore hypothesized that the “duodenal cloverleaf” discovered in our patient may be the outcome of a complicated duodenal ulcer, associated with chronic h. pylori infection and worsened by long-term nsaid use without concurrent ppi gastroprotection. |
| PubMedID- 22829807 | We recently investigated the prevalence of dupa and vir gene homologs and the associations between the status of dupa clusters and clinical outcomes in the us population and found that the presence of a complete dupa cluster increases the duodenal ulcer risk compared with h. pylori infection with incomplete dupa clusters or without the dupa gene independent of the cag pai status (adjusted or, 2.13; 95% ci = 1.13–4.03) . |
| PubMedID- 24963483 | Previous studies have established that a correlation exists between the development of duodenal ulcer in h. pylori infection and the level of apoptosis in antral mucosal epithelium . |
| PubMedID- 24598794 | duodenal ulceration was strongly associated with h. pylori infection (or 6.2 ; p<0.001). |
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