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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease drug rash with eosinophilia and systemic symptoms
Symptom C0014457|eosinophilia
Sentences 16
PubMedID- 23216243 Pustular-type drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms due to carbamazepine with systemic muscle involvement.
PubMedID- 23182063 Background: drug-induced hypersensitivity syndrome (dihs)/drug reaction with eosinophilia and systemic symptoms (dress) is a severe systemic hypersensitivity reaction caused by specific drugs, in which herpesvirus reactivations and organ dysfunction occur during the course of the disease.
PubMedID- 24749495 Background: drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms (dihs/dress) and stevens-johnson syndrome (sjs)/toxic epidermal necrolysis (ten) represent contrasting poles of severe drug eruptions, and sequential reactivations of several herpesviruses have exclusively been demonstrated in the former.
PubMedID- 19874350 Background: drug-induced hypersensitivity syndrome (dihs)/drug rash with eosinophilia and systemic symptoms (dress) syndrome is characterized by late disease onset, fever, rash, hepatic dysfunction, haematological abnormalities, lymphadenopathy and often, human herpesvirus (hhv) reactivation.
PubMedID- 24903194 The serum level of hmgb1 (high mobility group box 1 protein) is preferentially high in drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms.
PubMedID- 24635062 Increased ratio of foxp3+ regulatory t cells/cd3+ t cells in skin lesions in drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms.
PubMedID- 22666603 Symptoms of hsr can range from general manifestations, such as morbiliform rash, urticaria, angioedema, fever, malaise, anaphylaxis, bronchospasm, and erythema multiforme, to severe cutaneous adverse reactions (scar) such as drug-induced hypersensitivity syndrome (dihs)/drug reaction with eosinophilia and systemic symptoms (dress), and stevens-johnson syndrome (sjs)/toxic epidermal necrolysis (ten) .
PubMedID- 22380544 drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms syndrome induced by cilostazol and carbamazepine.
PubMedID- 25623158 drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (dihs/dress) is a severe adverse drug reaction caused by specific drug.
PubMedID- 22739739 drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (dihs/dress) is a severe drug-induced adverse reaction that in most cases occurs 3 to 6 weeks after drug administration .
PubMedID- 25156337 drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms with histologic features mimicking cutaneous pseudolymphoma.
PubMedID- 24517870 Tnf-alpha as a useful predictor of human herpesvirus-6 reactivation and indicator of the disease process in drug-induced hypersensitivity syndrome (dihs)/drug reaction with eosinophilia and systemic symptoms (dress).
PubMedID- 26110678 Purpose of review: severe adverse drug reactions (adrs) including stevens-johnson syndrome (sjs)/toxic epidermal necrolysis (ten) and drug-induced hypersensitivity syndrome (dihs)/drug reaction with eosinophilia and systemic symptoms (dress) are acute life-threatening conditions.
PubMedID- 20861604 The hhv-7 reactivation might be related to facial pustulosis, which is occasionally observed in drug-induced hypersensitivity syndrome/drug rash with eosinophilia and systemic symptoms.
PubMedID- 25547780 Differential expression profile of th1/th2-associated chemokines characterizes stevens-johnson syndrome/toxic epidermal necrolysis (sjs/ten) and drug-induced hypersensitivity syndrome/drug reaction with eosinophilia and systemic symptoms (dihs/dress) as distinct entities.
PubMedID- 23141052 Background: drug-induced hypersensitivity syndrome (dihs)/drug rash with eosinophilia and systemic symptoms (dress) is a serious acute drug reaction with fever, cutaneous eruption, lymphadenopathy, and several visceral dysfunctions.

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