eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | down syndrome |
| Symptom | C0028303|nondisjunction |
| Sentences | 2 |
| PubMedID- 23056758 | Such a profile might be seen in two conditions: isochromosome 21 or trisomy 21 with nondisjunction in meiosis ii without any crossing over occurred in meiosis i. qf-pcr could not differentiate these conditions, but karyotype analyses of that sample confirmed trisomy (fig. |
| PubMedID- 26017139 | down syndrome (ds, also known as trisomy 21) most often results from chromosomal nondisjunction during oogenesis. |
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