eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | cystic fibrosis |
| Symptom | C0021311|infections |
| Sentences | 163 |
| PubMedID- 21204916 | The opportunistic human pathogen, pseudomonas aeruginosa, is a major cause of life-threatening infections in patients with cystic fibrosis. |
| PubMedID- 20137066 | Background: burkholderia cepacia complex bacteria are opportunistic pathogens, which can cause severe respiratory tract infections in patients with cystic fibrosis (cf). |
| PubMedID- 25494960 | The ecotypes isolated from this long-term experimental evolution are similar to those commonly isolated from lung infections of persons with cystic fibrosis (cf) (zlosnik et al. |
| PubMedID- 25861381 | 2011), and even in chronic lung infections such as that of cystic fibrosis (konstan et al. |
| PubMedID- 24604671 | Background: viral respiratory tract infections in people with cystic fibrosis have a deteriorating effect on their lung function and disease progression. |
| PubMedID- 25741986 | Background: the antibiotics used to treat pulmonary infections in people with cystic fibrosis are typically chosen based on the results of antimicrobial susceptibility testing performed on bacteria traditionally grown in a planktonic mode (grown in a liquid). |
| PubMedID- 22035265 | For example, there are reports of falsely negative results of classic bacterial cultures on saliva samples in microbiological diagnostics of respiratory infections in patients with cystic fibrosis 4. |
| PubMedID- 20934258 | Pseudomonas aeruginosa is the major pathogen of chronic lung infections in individuals with cystic fibrosis (cf). |
| PubMedID- 24687506 | Evaluation of the pharmacokinetics and pharmacodynamics of liposomal amikacin for inhalation in cystic fibrosis patients with chronic pseudomonal infections using data from two phase 2 clinical studies. |
| PubMedID- 26356298 | A group of 17 closely related species, designated b. cepacia complex organisms, cause pulmonary infections primarily in patients with cystic fibrosis . |
| PubMedID- 24060984 | Purpose of review: this review summarizes some of the important recent findings concerning fungal airway infections in patients with cystic fibrosis (cf). |
| PubMedID- 22973562 | Micronized gentamicin powders have been delivered by the pulmonary route for the treatment of infections associated with cystic fibrosis (goldman et al., 1990), but there are no reports of the use of micronized antibiotics for tb treatment. |
| PubMedID- 24367355 | This genus includes several human pathogens among them the burkholderia cepacia complex, which are particularly important for causing chronic opportunistic infections especially in patients with cystic fibrosis or chronic granulomatous disease (mahenthiralingam et al., 2005; loutet and valvano, 2011). |
| PubMedID- 25267676 | Burkholderia cenocepacia is notorious for causing respiratory tract infections in people with cystic fibrosis. |
| PubMedID- 23235684 | Objectives: the objective of our review was to compare antibiotic treatment to no antibiotic treatment, or to compare different combinations of antibiotic treatment, for nontuberculous mycobacteria lung infections in people with cystic fibrosis. |
| PubMedID- 22940004 | There is clear evidence some viral infections are associated with cystic fibrosis that dual infection is more likely to produce symptoms, and mechanisms of viral-induced exacerbation should be elucidated. |
| PubMedID- 24232573 | Samples from wound infections and lungs of patients with cystic fibrosis often contains both p. aeruginosa and s. aureus, underscoring the clinical importance of co-infection by these two bacteria.24,25 it has been shown that interaction of p. aeruginosa and gram-positive bacteria including s. aureus can lead to increased virulence in p. aeruginosa.26 there is little information available about the interaction between these two bacterial pathogens and the importance of this interaction with regards to the severity and outcome of infection. |
| PubMedID- 22848580 | Burkholderia cenocepacia is an opportunistic pathogen that survives intracellularly in macrophages and causes serious respiratory infections in patients with cystic fibrosis. |
| PubMedID- 24704788 | In fact, biofilm communities exhibit increased tolerance towards conventional anti-microbial treatments and sterilization techniques and are responsible for many chronic infections associated with cystic fibrosis and endocarditis6,7 as well as nosocomial infections8. |
| PubMedID- 21912685 | Staphylococcus aureus causes chronic, recurrent endobronchial infections of patients with cystic fibrosis (cf) during childhood . |
| PubMedID- 23272096 | Burn wound infections, pneumonia, infections in patients with cystic fibrosis, intra-abdominal infections, chronic ulcers, and sepsis 6. |
| PubMedID- 22558432 | Background: given the polymicrobial nature of pulmonary infections in patients with cystic fibrosis (cf), it is essential to enhance our knowledge on the composition of the microbial community to improve patient management. |
| PubMedID- 19939932 | The burkholderia cepacia complex (bcc) is made up of at least 17 species of gram-negative opportunistic bacterial pathogens that cause fatal infections in patients with cystic fibrosis and chronic granulomatous disease. |
| PubMedID- 20643851 | The burkholderia cepacia complex (bcc) is a group of genetically related environmental bacteria that can cause chronic opportunistic infections in patients with cystic fibrosis (cf) and other underlying diseases. |
| PubMedID- 23152277 | Authors' conclusions: the current evidence is insufficient to recommend choosing antibiotics based on biofilm antimicrobial susceptibility testing rather than conventional antimicrobial susceptibility testing in the treatment of pseudomonas aeruginosa pulmonary infections in people with cystic fibrosis. |
| PubMedID- 21904046 | B. pseudomallei is closely related to b. mallei, the organism that causes glanders, and more distantly related to b. cenocepacia, an organism that causes acute infections in patients with cystic fibrosis. |
| PubMedID- 23305366 | This group of pathogens are responsible for chronic lung infections in people with cystic fibrosis and other immunocompromised individuals. |
| PubMedID- 23305368 | Furthermore, t3ss-expressing isolates are predominantly found in acute infections rather than in patients with cystic fibrosis, which indicates that t3ss is a detrimental virulence factor particularly in acute infections. |
| PubMedID- 20732993 | Aeruginosa and for understanding the role that innate immune cells, such as neutrophils, play in the host response to acute bacterial infections commonly associated with cystic fibrosis. |
| PubMedID- 22589289 | It is also an important opportunistic human pathogen and major contributor to chronic lung infections in patients with cystic fibrosis (cf). |
| PubMedID- 25666799 | Alginate is one of the three major pseudomonas exopolysaccharides, and it is only produced by mucoid strains that establish chronic infections in patients with cystic fibrosis (cf). |
| PubMedID- 24995163 | Liposomal ciprofloxacin has been further developed by aradigm corporation for pseudomonas aeruginosa infections in patients with cystic fibrosis and non-cystic fibrosis bronchiectasis. |
| PubMedID- 23363478 | Pseudomonas aeruginosa is an opportunistic human pathogen and a major cause of chronic infections in individuals with cystic fibrosis (cf). |
| PubMedID- 22023324 | Burkholderia cenocepacia, a member of the burkholderia cepacia complex, is an opportunistic pathogen that causes devastating infections in patients with cystic fibrosis. |
| PubMedID- 24040015 | B. multivorans is recognized as an important pathogen in nosocomial infections of patients with cystic fibrosis , although it has not been linked to an arthropod vector. |
| PubMedID- 24671511 | Scientific reports suggest p. aeruginosa as the most important pathogen and causal agent of chronic pulmonary infections in patients with cystic fibrosis, which leads to gradual and eventually fatal decline in pulmonary function (govan and deretic 1996). |
| PubMedID- 25013584 | Burkholderia cepacia is another important pathogen causing pulmonary infections in people with cystic fibrosis (cf). |
| PubMedID- 23824677 | Background: vancomycin is the drug-of-choice for the treatment of methicillin-resistant staphylococcus aureus (mrsa) infections in children with cystic fibrosis. |
| PubMedID- 25118167 | Methicillin-resistant staphylococcus aureus (mrsa) causes chronic pulmonary infections in patients with cystic fibrosis (cf). |
| PubMedID- 25445528 | Sodium colistimethate loaded lipid nanocarriers for the treatment of pseudomonas aeruginosa infections associated with cystic fibrosis. |
| PubMedID- 23802816 | Rationale: the efficacy of inhaled tobramycin on chronic pseudomonas aeruginosa infections in patients with cystic fibrosis (cf) has been established in clinical trials. |
| PubMedID- 21629778 | Studies of cough aerosols from pulmonary tuberculosis patients and cystic fibrosis patients with bacterial infections found that the concentration of infectious particles varied widely between patients , . |
| PubMedID- 24730990 | Bacteria of the burkholderia cepacia complex are the cause of severe lung infections primarily in patients with cystic fibrosis (cf). |
| PubMedID- 21106178 | Pseudomonas aeruginosa is a major hospital-associated pathogen that can cause severe infections, most notably in patients with cystic fibrosis or those hospitalized in intensive care units. |
| PubMedID- 25706529 | Pseudomonas aeruginosa is one of the major bacterial causes of respiratory infections- in patients with cystic fibrosis (cf), and contributes to acute exacerbations of chronic obstructive pulmonary disease, or bronchiectasis . |
| PubMedID- 22848443 | Pseudomonas aeruginosa (pa) is a ubiquitous opportunistic pathogen that is especially notorious for causing highly problematic, chronic infections within the lungs of cystic fibrosis (cf) and chronic obstructive pulmonary disease (copd) patients 1. |
| PubMedID- 21343449 | The antimicrobial and hemolytic activities of a host defense peptide can be controlled by its modification as a propeptide of reduced net charge, which can then be processed by neutrophil elastase, a serine protease involved in chronic airway inflammation and infections associated with cystic fibrosis. |
| PubMedID- 24039595 | Pseudomonas aeruginosa is the dominating pathogen of chronic airway infections in patients with cystic fibrosis (cf). |
| PubMedID- 23481089 | However whether and how it can be used for the treatment of bacterial lung infections in patients with cystic fibrosis is unclear. |
| PubMedID- 21555402 | Pseudomonas aeruginosa, an opportunistic pathogen of clinical importance, causes chronic airway infections in patients with cystic fibrosis (cf). |