eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | cushing syndrome |
| Symptom | C0020456|hyperglycemia |
| Sentences | 4 |
| PubMedID- 23558873 | Background: mifepristone is approved to control hyperglycemia in adults with endogenous cushing's syndrome and is described as a mildly qtc prolonging drug, based on a tqt study. |
| PubMedID- 22837948 | Could one have imagined, at that time, that this would go on to be used for treatment of an adrenal disorder, and one day be approved to control hyperglycemia in adults with endogenous cushing's syndrome? |
| PubMedID- 25560275 | Mifepristone, a glucocorticoid receptor antagonist, has been approved for hyperglycemia associated with cushing's syndrome based on the results of a prospective study where it produced in the majority of patients' significant clinical and metabolic improvement. |
| PubMedID- 22674211 | Mifepristone (a glucocorticoid receptor antagonist) is another promising drug, recently approved by the fda for treatment of hyperglycemia associated with cushing's syndrome. |
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