eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | cryoglobulinemia |
| Symptom | C1960443|vasculitic neuropathy |
| Sentences | 1 |
| PubMedID- 24797167 | For example, ss is characterized by promiscuous b-cell dysregulation and the induction of both pathogenic and nonpathogenic antibodies.2,18,22,23,76 in this regard, one cause of mononeuritis multiplex may be a vasculitic neuropathy associated with cryoglobulinemia and subsequent immune-complex deposition in the vasa nervorum.58 in addition, ss is characterized by the homing and infiltration of lymphocytes to different end organs.22,37,69,70 there is accordingly a spectrum of neuropathies characterized by lymphocytic infiltration of the dorsal root ganglia (drg) and other ganglionic elements, including the sensory neuronopathies (characterized by proprioceptive loss that can affect entire limbs), painful small-fiber neuropathies (see below), facial pain disorders (such as trigeminal neuropathies), and subtypes of autonomic neuropathies.8,13,28,51,58,64 the evaluation for peripheral neuropathies may require an exhaustive assessment including elicitation of symptoms, neurologic examination, and appropriate ancillary studies. |
Page: 1