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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease conn syndrome
Symptom C0020538|hypertension
Sentences 27
PubMedID- 24831672 This nomogram can help clinicians calculate the probability of postoperative hypertension cure in patients with primary aldosteronism and objectively inform them of their hypertension outcome before laparoscopic adrenalectomy.
PubMedID- 21822477 They point out that the incidence of primary aldosteronism in patients with drug resistant hypertension is 14% to 23%, which is much higher than in the general hypertensive population.
PubMedID- 26574803 primary aldosteronism is the cause of hypertension in 5-10% of the hypertensive population.
PubMedID- 22739770 22-year-old patient with malignant hypertension associated with primary aldosteronism.
PubMedID- 21785705 Prevalence of resistant hypertension in patients with primary hyperaldosteronism is 17–22%, higher than in the general hypertensive population.
PubMedID- 25336886 Description of the case: we describe a case of a 71-year-old female patient with uncontrollable hypertensive peaks in soils of pre-existing arterial hypertension, who was diagnosed with primary aldosteronism.
PubMedID- 26074961 hypertension due to primary aldosteronism had long been considered a form of disease associated with a relatively low incidence of cardiovascular and renal complications .
PubMedID- 21234416 Particularly in patients with resistant hypertension, the prevalence of primary aldosteronism has been found between 10% and 20% .
PubMedID- 23102075 The main determinants of surgical cure or control of hypertension in patients with primary hyperaldosteronism were duration of hypertension, number of antihypertensive medications, preoperative response to spironolactone, the presence of adenoma, and cyp11b2 (344 c/t) genotype.
PubMedID- 24285684 Context: the molecular mechanisms of primary aldosteronism, a common cause of human hypertension, are unknown, but alterations of k(+) channels can play a key role.
PubMedID- 24006040 Prevalence of and risk factors for primary aldosteronism among patients with resistant hypertension in china.
PubMedID- 23913001 Matched apa and venous blood dnas were obtained from patients undergoing adrenalectomy for hypertension with primary aldosteronism and adrenocortical tumor at yale new haven hospital, uppsala university hospital, and montefiore medical center and albert einstein college of medicine, and were evaluated as previously described1.
PubMedID- 20508722 Furthermore we showed that hemin improved insulin-signaling/glucose metabolism in deoxycorticosterone-acetate (doca) hypertension, a model of primary aldosteronism , suggesting a role of the ho system against dysfunctional glucose metabolism in aldosteronism.
PubMedID- 25907736 We performed exome sequencing of 40 unrelated subjects with hypertension due to primary aldosteronism by age 10.
PubMedID- 22026274 Clear cell carcinoma of the kidney and conn's syndrome in a patient with arterial hypertension--a case report.
PubMedID- 24133375 While the finding of primary aldosteronism in patients with resistant hypertension is in the order of 20%, such patients respond to mr antagonists no differently from the remainder without elevated aldosterone levels, suggesting that mr activation may be equally important in patients with and without an established diagnosis of primary aldosterone.
PubMedID- 26273475 We describe a young male patient with longstanding hypertension, who was diagnosed with primary hyperaldosteronism and treated by an attempted retroperitoneoscopic total unilateral adrenalectomy for a left-sided presumed aldosterone-secreting adenoma.
PubMedID- 23635457 The prevalence of hypertension after adrenalectomy in patients with primary aldosteronism.
PubMedID- 23808747 primary hyperaldosteronism: common cause of secondary hypertension with higher cardiovascular risk.
PubMedID- 25546991 Difficulty in diagnosis of primary hyperaldosteronism as the cause of resistant hypertension and severe hypokalemia--case report.
PubMedID- 24944753 Management of hypertension in primary aldosteronism.
PubMedID- 22311906 Chronic aldosterone administration increases glomerular filtration rate, whereas inhibition of mineralocorticoid receptors (mrs) markedly attenuates glomerular hyperfiltration and hypertension associated with primary aldosteronism or obesity.
PubMedID- 23470690 One common cause of secondary hypertension, often associated with hypokalemia, is primary hyperaldosteronism or conn syndrome.
PubMedID- 23828574 Another possible explanation for this discrepancy is that one study could have included fewer patients with hypertension due to primary aldosteronism in relation to the other study.
PubMedID- 23087856 Rarely, hypertension is absent in patients with primary aldosteronism.
PubMedID- 21451421 Conclusion: the antihypertensive effect of spironolactone was significantly greater than that of eplerenone in hypertension associated with primary aldosteronism.
PubMedID- 24864141 primary aldosteronism represents major cause of secondary hypertension, strongly associated with high cardiovascular morbidity and mortality.

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