| Disease | chronic pain |
| Symptom | C0041696|major depression |
| Sentences | 2 |
| PubMedID- 25370278 | major depression in patients with chronic pain is associated with decreased function, poorer treatment response and increased health care costs. |
| PubMedID- 22629287 | Finally, chronic pain may be associated with major depression, which complicates treatment, and which must be diagnosed and independently treated for successful pain management. |
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