eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | chronic pain |
| Symptom | C0013146|drug abuse |
| Sentences | 1 |
| PubMedID- 26338332 | Although chronic opioid administration may alter pain states, the presence of pain itself may alter the propensity to self-administer opioids, and previous history of drug abuse comorbid with chronic pain promotes higher rates of opioid misuse. |
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