eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | chronic myelocytic leukemia |
| Symptom | C1516669|clonal evolution |
| Sentences | 3 |
| PubMedID- 21264552 | A novel insertion mutation of k294rgg within bcr-abl kinase domain confers imatinib resistance: sequential analysis of the clonal evolution in a patient with chronic myeloid leukemia in blast crisis. |
| PubMedID- 25212276 | To study clonal evolution in chronic myeloid leukemia (cml), we searched for bcr-abl-independent gene mutations in both philadelphia chromosome (ph)-negative and ph-positive clones in 29 chronic-phase cml patients by targeted deep sequencing of 25 genes frequently mutated in myeloid disorders. |
| PubMedID- 20499401 | Survival outcomes for clonal evolution in chronic myeloid leukemia patients on second generation tyrosine kinase inhibitor therapy. |
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