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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease chronic myelocytic leukemia
Symptom C0005699|blast crisis
Sentences 28
PubMedID- 21510902 The imatinib-sensitive bcr/abl+ cml-t1 cell line (t-lineage blast crisis of human chronic myeloid leukemia, purchased from dsmz, braunschweig, de) was used to perform synergism studies.
PubMedID- 26199254 Here, we report of a patient with chronic myelogenous leukemia in blast crisis and with pulmonary failure due to leukostasis who recovered after a combination therapy of leukapheresis and imatinib treatment.
PubMedID- 22699066 Objective: to identify differentially expressed genes between chronic phase and blast crisis in chronic myeloid leukemia, explore the mechanism and screen potential biomarkers of disease progression.
PubMedID- 25860287 Cml-bc: chronic myeloid leukemia in blast crisis.
PubMedID- 24371785 The diagnosis was extramedullary myeloid blast crisis of chronic myelogenous leukemia (cml).
PubMedID- 22379297 Central nervous system blast crisis in chronic myeloid leukemia on imatinib mesylate therapy: report of two cases.
PubMedID- 22564882 Another reason for enhanced pi3k/akt/mtor signaling in ph+ b-all is due to the fact pp2a is functionally inactivated during the blast crisis of chronic myelogenous leukemia through the inhibitory activity of set protein, which is regulated by bcr-abl .
PubMedID- 26030751 Multiple copies of bcr/abl fusion signals and t(3;21) in a chronic myeloid leukemia: patient with blast crisis - a rare event with imatinib mesylate (gleevec)-resistance in an indian patient.
PubMedID- 21698118 The human nk-sensitive k562 (chronic myelogenous leukemia in blast crisis) and u-937 (acute myeloid monocytic leukemia) cell lines were used as target cells.
PubMedID- 25667640 Extramedullary t-lymphoblastic blast crisis in chronic myelogenous leukemia: a case report of successful diagnosis and treatment.
PubMedID- 25814082 Management of chronic myeloid leukemia in blast crisis.
PubMedID- 22923928 in blast crisis of chronic myeloid leukemia and occasionally in warm autoimmune hemolytic anemia.
PubMedID- 24825862 Hes1 promotes blast crisis in chronic myelogenous leukemia through mmp-9 upregulation in leukemic cells.
PubMedID- 25933373 chronic myeloid leukemia in blast crisis (cml bc) remains a challenging disease to treat despite the introduction and advances in tyrosine kinase inhibitor (tki) therapy.
PubMedID- 24959052 3 it is frequently seen in association with other myeloproliferative disorders such as acute myeloid leukemia (aml) and the blast crisis stage of chronic myeloid leukemia.
PubMedID- 22176774 The hematological and clinical parameters were consistent with aml-m4 e0 that resembles blast crisis of chronic myeloid leukemia (cml).
PubMedID- 24330849 Transduction of primary blast cells from chronic myeloid leukemia in blast crisis (cml-bc) and ph-positive acute lymphoblastic leukemia (all) with p16(ink4a) or p14(arf) virus also resulted in cell growth inhibition and/or apoptosis with a patient-to-patient variation, whereas clonal growth and differentiation of cord blood progenitor cells were not affected by enforced expression of ink4a/arf.
PubMedID- 23899072 We describe such a case of chronic myelogenous leukemia in blast crisis in a previously healthy 61-year-old woman.
PubMedID- 26411119 Characteristics and outcomes of patients with chronic myelogenous leukemia in blast crisis.
PubMedID- 23826587 Pediatric chronic myeloid leukemia with b-cell lymphoid blast crisis at presentation.
PubMedID- 25789076 Dasatinib as the salvage therapy for chronic myeloid leukemia with blast crisis and central nervous system involvement: a case report.
PubMedID- 25688862 K562 cell is a bipotent cell line established from a patient in a blast crisis of chronic myeloid leukemia, it possesses variable capacities of differentiation toward erythroid and megakaryocytic cell lineages.
PubMedID- 26155548 Novel cytogenetic aberrations in a patient of chronic myeloid leukemia with blast crisis.
PubMedID- 22475357 Sudden blast crisis in chronic myeloid leukemia treated with tyrosine kinase inhibitors.
PubMedID- 22140534 K562 cells are derived from blast crisis of chronic myelogenous leukaemia patient and has been shown to undergo erythroid differentiation upon various stimulations such as haemin and chemotherapeutic agents, .
PubMedID- 22792345 The demethylating drug has been shown to be effective in treating patients with myelodysplastic syndrome (mds) and blast crisis of chronic myelogenous leukemia (cml-bl) , .
PubMedID- 22139798 Background: patients with chronic myelogenous leukemia (cml) in blast crisis have a poor response to tyrosine kinase inhibitors designed to inhibit the breakpoint cluster region-v-abelson murine leukemia viral oncogene homolog 1 (bcr-abl1) oncogene.
PubMedID- 25745544 Bone involvement can also rarely occur in acute lymphoblastic leukemia and blast crisis of chronic myeloid leukemia.12 other tumor presenting with predominant bone destruction at this age is ewing’s sarcoma.

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