eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | chronic granulomatous disease |
| Symptom | C0021311|infections |
| Sentences | 12 |
| PubMedID- 25537872 | Editorial commentary: severe infections in patients with chronic granulomatous disease. |
| PubMedID- 23108438 | Streptococcal infections in patients with chronic granulomatous disease: case report and review of the literature. |
| PubMedID- 24669841 | Moreover, limited evidence suggests that recombinant ifn-γ (rifn-γ) has a beneficial effect on the outcome of fungal infections in patients with chronic granulomatous disease (cgd) , hiv , leukemia , and in patients receiving organ transplants . |
| PubMedID- 23654055 | Invasive fungal infections in patients with chronic granulomatous disease. |
| PubMedID- 22319454 | Ncf1 codes for p47phox, a critical subunit in the assembly of nadph oxidase (nox); homozygous deficiency accounts for 20% of patients with chronic granulomatous disease, a disorder associated with repeated infections due to an inability to kill bacteria. |
| PubMedID- 21204900 | Primary defects in oxidase activity in chronic granulomatous disease (cgd) lead to severe, life-threatening infections that demonstrate the importance of the oxygen-dependent microbicidal system in host defence. |
| PubMedID- 22371289 | Streptococcal infections in patients with chronic granulomatous disease: case report and review of the literature. |
| PubMedID- 20226292 | Other reports expanded the clinical spectrum of disease and improved the characterization of conditions such as warts, hypogammaglobulinemia, and myelokathexis syndrome or the occurrence of mucormycosis and serratia species infections in patients with chronic granulomatous disease. |
| PubMedID- 23340515 | These two patients suffer from chronic granulomatous disease with increased microbial infections in addition to wbs. |
| PubMedID- 24710301 | Interestingly, b. cepacia that causes onion rot can also cause life-threatening pulmonary infections in individuals with chronic granulomatous disease, or cystic fibrosis (cf) . |
| PubMedID- 25900657 | Also, although the extent to which mpo deficiency increases susceptibility to microbial infection is debated in the field (a substantial proportion of individuals with mpo deficiency are asymptomatic), it is clear that mpo deficiency does not lead to the severe susceptibility to infections observed in patients with chronic granulomatous disease, a disorder of the phagocyte nadph oxidase (12, 13). |
| PubMedID- 23030328 | infections associated with chronic granulomatous disease: linking genetics to phenotypic expression. |
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