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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease cardiomyopathy
Symptom C0028754|obesity
Sentences 8
PubMedID- 24342999 However, the molecular mechanisms linking obesity with cardiomyopathy are probably multifactorial and depend as much on the genetics of the individual as on environmental factors such as circulating cytokines and chemokines.
PubMedID- 25018087 obesity-induced cardiomyopathy may be mediated by alterations in multiple signaling cascades involved in glucose and lipid metabolism.
PubMedID- 23508767 Diabetes and obesity are both associated with lipotoxic cardiomyopathy exclusive of coronary artery disease and hypertension.
PubMedID- 24614171 Many studies have shown that mitochondrial biogenesis and function are impaired in lipotoxic cardiomyopathy associated with obesity and diabetes , and that mitochondrial dysfunction is linked to cardiac dysfunction .
PubMedID- 23817015 Background: although obesity increases the risk of developing cardiomyopathy, the mechanisms underlying the development of this cardiomyopathy are incompletely understood.
PubMedID- 23978095 The role of obesity in cardiomyopathy and nephropathy.
PubMedID- 22465089 The cardiomyopathy seen with obesity is associated with increased interstitial fibrosis and diastolic dysfunction.
PubMedID- 23196711 obesity-related diabetes mellitus leads to lipotoxic cardiomyopathy resulting in a form of cardiac dysfunction.

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