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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease bronchiolitis obliterans
Symptom C1145670|respiratory failure
Sentences 4
PubMedID- 24985544 bronchiolitis obliterans (bo) with progressive respiratory failure is a significant cause of death in pnp.
PubMedID- 20051789 Patient: a pediatric patient affected by bronchiolitis obliterans with refractory hypercapnic respiratory failure.
PubMedID- 24626654 However, thedisease is generally resistant to therapy.99,105 the mortality ofpatients with pnp is 75% to 90%.101respiratory failure due to bronchiolitis obliterans is one of the most important causesof death in patients with pnp/pams.85,97,99 however, a recent study, conducted in france, has made a valuablecontribution to evaluating the prognosis of pnp.101 the authors analysed patients from 27 different medical centers,demonstrating that the disease course is highly variable, not only in severe cases, butalso in indolent disease, and that prognosis is worst in the presence of erythemamultiforme-like lesions and of necrotic keratinocytes in histopathological exam.
PubMedID- 26413127 Several studies described that the excessive consumption of sauropus androgynus could cause drowsiness, constipation, and bronchiolitis obliterans and may lead to respiratory failure.

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