eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | basal cell nevus syndrome |
| Symptom | C0007117|basal cell carcinoma |
| Sentences | 5 |
| PubMedID- 21668511 | Conclusion: methylaminolevulinate-photodynamic therapy seems an interesting option for the treatment of basal cell carcinomas in patients with basal cell nevus syndrome. |
| PubMedID- 25148279 | Axillary basal cell carcinoma in patients with goltz-gorlin syndrome: report of basal cell carcinoma in both axilla of a woman with basal cell nevus syndrome and literature review. |
| PubMedID- 24898076 | Importance: basal cell carcinomas (bccs) in patients with gorlin syndrome have been reported to be extremely sensitive to smoothened (smo) inhibitors, a novel targeted therapy against the hedgehog pathway, because of characteristic mutations in these patients. |
| PubMedID- 24698937 | Goltz-gorlin syndrome presents with multiple basal cell carcinomas, odontogenic keratocysts, and cutaneous cysts, among other manifestations. |
| PubMedID- 23036338 | A phase ii, randomized, placebo-controlled trial in gorlin syndrome patients with basal cell carcinoma concluded that vismodegib was significantly better than placebo at reducing new basal cell carcinoma lesions (p < 0.001) and at decreasing the sum of the longest diameter of existing lesions (p = 0.003). |
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