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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease barrett esophagus
Symptom C0001418|adenocarcinoma
Sentences 56
PubMedID- 23617672 It is often difficult to accurately delineate the borders and extent of early-stage esophageal adenocarcinoma in patients with barrett's esophagus using conventional white light endoscopy.
PubMedID- 20610142 In contrast to adenocarcinoma arising from barrett's esophagus in western countries, the major disease phenotype in the asia-pacific region is esophageal squamous cell carcinoma which is attributed to the prevalence of smoking, alcohol, and betel quid chewing.
PubMedID- 19660251 Rapid progression of barrett's esophagus into adenocarcinoma in a combined lung and kidney transplant recipient.
PubMedID- 25071359 Lifetime risk of esophageal adenocarcinoma in patients with barrett's esophagus.
PubMedID- 22219077 Risk of adenocarcinoma in patients with barrett esophagus is significantly less than previously assumed.
PubMedID- 26233550 Serum 25-hydroxyvitamin d levels and the risk of dysplasia and esophageal adenocarcinoma in patients with barrett's esophagus.
PubMedID- 24570878 As exemplified in esophageal adenocarcinoma, the early detection of barrett esophagus (be) with low- or high-grade dysplasia (hgd) might represent the most attractive goal to achieve a cure.
PubMedID- 26208896 Background & aims: statins have been reported to protect against esophageal adenocarcinoma (eac) in patients with barrett's esophagus (be).
PubMedID- 22241250 Use of statin medications and risk of esophageal adenocarcinoma in persons with barrett's esophagus.
PubMedID- 23338150 Therefore, telomerase inhibitors may exhibit high potency in the treatment of esophageal adenocarcinoma arising from barrett's esophagus.
PubMedID- 26202380 Overexpression of cd55 from barrett's esophagus is associated with esophageal adenocarcinoma risk.
PubMedID- 21857838 barrett esophagus with progression to adenocarcinoma in multiple family members with attenuated familial polyposis.
PubMedID- 21820152 The findings of this study improve our understanding of the role that chromosomal instability and alterations of tumor suppressor genes such as cdkn2a and oncogenes such as erbb2 play in the progression of intestinal metaplasia to adenocarcinoma in patients with barrett's esophagus.
PubMedID- 25633286 Nsaids, statins, low-dose aspirin and ppis, and the risk of oesophageal adenocarcinoma among patients with barrett's oesophagus: a population-based case-control study.
PubMedID- 24968432 Pathological diagnosis was adenocarcinoma with barrett's esophagus.
PubMedID- 25621687 The incidence of esophageal adenocarcinoma arising from barrett esophagus (be) has been rapidly increasing in many western countries over the past few decades.1–3 it also leads to increasing the rate of hospitalization for esophageal adenocarcinoma and causes a serious problem.4 endoscopic surveillance of be, the currently accepted standard, aims to reduce morbidity and mortality by early detection and endoscopic therapy of dysplasia or cancer.5–8 current guidelines from gastroenterology societies recommend endoscopic surveillance of be using white light endoscopy (wle) with targeted biopsies of any endoscopically visible lesions and 4 random quadrant biopsies from every 2 cm of the be segment (seattle protocol).7,9 however, it has been pointed out that this protocol has several limitations, such as time required, low compliance, and increased risk of sampling error.10 therefore, establishment of a more effective surveillance program for detecting dysplastic lesions or those with high malignant potential in be patients is highly desirable.
PubMedID- 24681073 Preference of endoscopic ablation over medical prevention of esophageal adenocarcinoma by patients with barrett's esophagus.
PubMedID- 22302717 There is a critical need to identify molecular markers that can reliably aid in stratifying esophageal adenocarcinoma (eac) risk in patients with barrett's esophagus.
PubMedID- 21309910 Dysplasia and esophageal adenocarcinoma may arise in patients with barrett's esophagus after fundoplication esophageal ph monitoring showing no acid in esophagus.
PubMedID- 26311716 Surveillance endoscopy is associated with improved outcomes of oesophageal adenocarcinoma detected in patients with barrett's oesophagus.
PubMedID- 23591735 We suggest that it may be useful to stratify the risk of adenocarcinoma in patients with barrett's esophagus.
PubMedID- 23617676 We report herein a case of adenocarcinoma arising from short-segment barrett's esophagus (ssbe) in a 36-year-old man.
PubMedID- 21143918 There are few clear prognostic indicators of susceptibility to developing oesophageal adenocarcinoma although patients with barrett's oesophagus are thought to be more at risk to developing oesophageal adenocarcinoma.
PubMedID- 26068095 We explored next-generation sequencing to detect mutations with the analytical sensitivity required to predict concurrent high-grade dysplasia (hgd) and esophageal adenocarcinoma (eac) in patients with barrett's esophagus by testing nonneoplastic bim.
PubMedID- 20188100 Medications (nsaids, statins, proton pump inhibitors) and the risk of esophageal adenocarcinoma in patients with barrett's esophagus.
PubMedID- 26426603 Cost-effectiveness decision tree model of endoscopic surveillance for esophageal adenocarcinoma among patients with definite barrett's esophagus.
PubMedID- 24221456 Acid-suppressive medications and risk of oesophageal adenocarcinoma in patients with barrett's oesophagus: a systematic review and meta-analysis.
PubMedID- 22796132 Background& aims: proton pump inhibitors and nonsteroidal anti-inflammatory drugs might prevent esophageal adenocarcinoma in patients with barrett's esophagus (be), but there are limited data from clinical trials to support this concept.
PubMedID- 23111465 While some studies suggest ppis result in a significant reduction in the risk of developing dysplasia and adenocarcinoma in patients with barrett's esophagus, others suggest that ppis have no effect.
PubMedID- 24570884 In the united states, the burden of esophageal cancer in 2007 was 16,640 new cases and 14,500 deaths with a 5-year survival rate of only 15%.1 of these cases, 65% were adenocarcinoma associated with barrett esophagus (be).
PubMedID- 25708344 Oesophagectomy is a safe option for early adenocarcinoma arising from barrett's oesophagus.
PubMedID- 21995385 Incidence of adenocarcinoma among patients with barrett's esophagus.
PubMedID- 23714382 Background & aims: recent population-based studies have shown a low risk of esophageal adenocarcinoma (eac) in patients with nondysplastic barrett's esophagus (ndbe).
PubMedID- 20698040 The annual incidence of adenocarcinoma arising from barrett's esophagus (be) is approximately 0.5%.
PubMedID- 23243384 For upper gi tract pathology i-scan assisted in diagnosis or therapy of barrett's esophagus with dysplasia, esophageal adenocarcinoma, hsv esophagitis, gastric malt lymphoma, gastric antral intestinal metaplasia with dysplasia, duodenal follicular lymphoma, and a flat duodenal adenoma.
PubMedID- 24737143 Aspirin has been proposed in recent years as a candidate for chemoprevention of adenocarcinoma in patients with barrett's esophagus.
PubMedID- 20550712 The 'exercise and the prevention of oesophageal cancer study' will determine whether 24 weeks of exercise training will lead to alterations in risk factors or biomarkers for oesophageal adenocarcinoma in males with barrett's oesophagus.
PubMedID- 20397052 Oral bisphosphonate prescriptions and the risk of esophageal adenocarcinoma in patients with barrett's esophagus.
PubMedID- 25843080 Acid-suppressive medications and risk of esophageal adenocarcinoma in patients with barrett's esophagus(gut 2014;63:1229-1237).
PubMedID- 24605249 Observational studies have shown that non-steroidal anti-inflammatory drugs could reduce the adenocarcinoma incidence in patients with barrett's esophagus by 41%, while statins could reduce the risk by 43%.
PubMedID- 24651385 Cyclooxygenase inhibitors use is associated with reduced risk of esophageal adenocarcinoma in patients with barrett's esophagus: a meta-analysis.
PubMedID- 21115135 The incidence of esophageal adenocarcinoma among patients with nondysplastic barrett's esophagus has been overestimated.
PubMedID- 24212953 Epidemiologic studies showed that long-term use of ppi was associated with lower rates of dysplasia and adenocarcinoma in patients with barrett's esophagus .
PubMedID- 23453294 Patients: we studied 23 consecutive patients who underwent complete cesd for superficial esophageal carcinoma (22 squamous cell carcinomas and 1 adenocarcinoma associated with barrett's esophagus).
PubMedID- 24795040 Background: proton pump inhibitors (ppis) may reduce the risk of esophageal adenocarcinoma (eac) in patients with barrett's esophagus.
PubMedID- 21593708 Incidence of esophageal adenocarcinoma with barrett esophagus (be) imposes a decision about therapy management.
PubMedID- 22626608 Background & aims: radiofrequency ablation (rfa) reduces the risk of esophageal adenocarcinoma (eac) in patients with barrett's esophagus (be) with high-grade dysplasia (hgd), but its effects in patients without dysplasia are debatable.
PubMedID- 22014070 Among several genetic abnormalities, both kras and erbb2 amplification have been indicated as early events in adenocarcinoma development of barrett's esophagus .
PubMedID- 19850156 Risk of esophageal adenocarcinoma and mortality in patients with barrett's esophagus: a systematic review and meta-analysis.
PubMedID- 20937048 Aim: to assess the effect of 40 mg twice daily esomeprazole (high-dose) on gastric and oesophageal ph and symptoms, and biomarkers relevant to adenocarcinoma, in patients with barrett's oesophagus (bo).

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