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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease b-cell chronic lymphocytic leukemia
Symptom C0850497|immune deficiency
Sentences 2
PubMedID- 20070151 Ribosome-lamella complexes in the peripheral blood of patients with chronic lymphocytic leukemia are associated with serological immune deficiency.
PubMedID- 24198926 The pharmacokinetics of ivig shows considerable intra- and interpopulation variability among patients with normal immunoglobulin levels, patients with primary immunodeficiency diseases, bone marrow transplant recipients, patients with immune deficiency due to chronic lymphocytic leukemia, or in some other diseases.17 in different pharmacokinetic studies in pediatric primary immunodeficiency patients, igg half-life was found to be between 30.9±11.3 and 50.8±30.3 days.18-20 our patients received ivig therapy at 6-8 week intervals because of some social and economical problems, and the variable half-life of ivig among patients.

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