eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | atypical mole |
| Symptom | C0025202|melanoma |
| Sentences | 7 |
| PubMedID- 23381582 | Our data showed that fbw7 expression is significantly reduced in primary melanoma compared with dysplastic nevi (p=0.020) and further reduced in metastatic melanoma compared with primary melanoma (p=0.011). |
| PubMedID- 24499631 | Showed that nqo1 expression is significantly increased in primary melanomas compared with dysplastic nevi and this may occur in the initiation stage of melanoma development. |
| PubMedID- 22970236 | Also revealed that nuclear p27kip1 expression was reduced in primary melanomas compared with dysplastic nevi and further reduced in metastatic melanoma, whereas the cytoplasmic p27kip1 was increased in primary and metastatic melanomas compared with dysplastic nevi . |
| PubMedID- 20952589 | Sox4 expression was remarkably reduced in metastatic melanoma compared with dysplastic nevi (p < 0.05) and primary melanoma (p < 0.01). |
| PubMedID- 25954957 | The results showed that nrp1 expression was significantly reduced in common nevi and dysplastic nevi, compared with primary melanoma and metastatic melanoma. |
| PubMedID- 24130172 | In fact, kai1 expression is drastically reduced in primary melanoma compared with dysplastic nevi (p = 1.8x10(-4)) and further reduced in metastatic melanoma compared with primary melanoma (p = 9.4 x 10(-15)). |
| PubMedID- 24927342 | Wang et al11 showed decreased ing3 expression in malignant melanoma in comparison with dysplastic nevi and gunduz et al1228 found allelic loss and reduced expression of the ing3 in human head and neck cancers, in line with our findings. |
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