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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease anemia, pernicious
Symptom C0017152|gastritis
Sentences 9
PubMedID- 26405069 Autoantibodies targeting the h+/k+-atpase proton pump of the gastric parietal cell (parietal cell antibodies pca) are diagnostic of atrophic body gastritis (abg) leading to pernicious anemia (pa).
PubMedID- 25681243 Single nucleotide polymorphisms related to vitamin b12 serum levels in autoimmune gastritis patients with or without pernicious anaemia.
PubMedID- 23053499 There are conflicting views about the association between type a gastritis with pernicious anemia (pa) and infection with helicobacter pylori, and currently, no definite conclusion has been reached.
PubMedID- 22261919 The fsg alone is not adequate to make the diagnosis of zes, because hypergastrinemia can be caused by hypochlorhydria/achlorhydria (chronic atrophic fundus gastritis, often associated with pernicious anemia) as well as other disorders causing hypergastrinemia with hyperchlorhydria besides zes (helicobacter pylori infection, gastric outlet obstruction, renal failure, antral g-cell syndromes, short bowel syndrome, retained antrum) .
PubMedID- 21947876 pernicious anemia is associated with atrophic body gastritis, whose diagnostic criteria are based on the histologic evidence of gastric body atrophy associated with hypochlorhydria.
PubMedID- 25437608 The prevalence of pernicious anemia resulting from autoimmune gastritis has been estimated as 127 cases/100,000 inhabitants in northern europe including united kingdom, denmark, and sweden .
PubMedID- 23314667 Although it depends on the series, approximately 25% of apeced patients are affected by gastrointestinal (gi) manifestations, mainly autoimmune-related disorders like autoimmune hepatitis, atrophic gastritis with or without pernicious anemia (biermer disease), intestinal infections, and malabsorption.
PubMedID- 24109480 Autoimmune gastritis with pernicious anemia is present in approximately 30% of patients by middle age (9).
PubMedID- 21225628 pernicious anemia, a condition with chronic gastritis and achlorhydria, is strongly associated with gastric carcinoma.

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