eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | amyotrophic lateral sclerosis |
| Symptom | C0037036|sialorrhea |
| Sentences | 6 |
| PubMedID- 23517881 | Conclusion: salivary gland radiotherapy effectively reduced sialorrhea in patients with amyotrophic lateral sclerosis. |
| PubMedID- 22837969 | Botulinum toxin injections into the salivary glands have been proposed for treating sialorrhea in patients with amyotrophic lateral sclerosis or other neurologic disorders since 1997.8 bont-a, used as a spasticity treatment, weakens the muscles for 3-4 months.9 as in the salivary gland, the effect of the bont-a injection was reported to last for 6 months.6,10 in our study, overall therapeutic effects were persisted significantly for up to 9 months (p<0.05). |
| PubMedID- 23134507 | Validation of robust tools to measure sialorrhea in amyotrophic lateral sclerosis: a study in a large french cohort. |
| PubMedID- 24466514 | In 1997, bushara hypothesized that the injection of botulinum toxin into parotid glands in amyotrophic lateral sclerosis with severe sialorrhea was therapeutic. |
| PubMedID- 21726879 | Unilateral parotid electron beam radiotherapy as palliative treatment for sialorrhea in amyotrophic lateral sclerosis. |
| PubMedID- 26174654 | Radiotherapy treatment of sialorrhea in patients with amyotrophic lateral sclerosis requiring non-invasive ventilation. |
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