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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease al amyloidosis
Symptom C0032227|pleural effusion
Sentences 2
PubMedID- 21267391 Indeed, in a study comparing 35 al amyloidosis patients with pleural effusion versus 120 patients without effusion, no significant differences were found in left ventricular indices, pulmonary pressure, or degree of nephrosis.10) furthermore, both gross and microscopic examination of pleural surface identified the presence of amyloid deposit,10)12) lending strong support to amyloid infiltration being a major factor.
PubMedID- 20955545 However, further investigations are needed to elucidate the relationship between vegf and refractory pleural effusion associated with systemic al amyloidosis because the complete reduction of pleural effusion was observed in only two of the five patients reported to be treated with bevacizumab .

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