eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hepatitis c |
| Symptom | |infection |
| Sentences | 461 |
| PubMedID- 19858727 | Background/aim: infection with hepatitis c virus (hcv) frequently results in a persistent infection, suggesting that it has evolved efficient mechanism(s) for blocking the host cell's innate antiviral response. |
| PubMedID- 22703595 | In particular, the impact of co-infection with hepatitis c virus (hcv) on treatment response is still controversial despite the large number of published data. |
| PubMedID- 21520209 | We investigated the susceptibility of heparg hepatocytes to in vitro infection with serum-derived hepatitis c virus (hcv) particles (hcvsp) and the potential neutralizing activity of the e1e2-specific monoclonal antibody (mab) d32.10. |
| PubMedID- 22829850 | infection with hepatitis c virus (hcv) is affecting about 3% of the world's population, leading to liver damage, end-stage liver disease, and development of hepatocellular carcinoma, being thus the first indication for liver transplantation in the usa. |
| PubMedID- 24077625 | It still remains unclear how occult hbv infection affects the treatment of chronic hepatitis c. |
| PubMedID- 24273918 | Background: the rate of hepatocellular carcinoma (hcc) is increasing in egypt where the major risk factor is chronic infection with hepatitis c virus (hcv). |
| PubMedID- 21994686 | Hbv infection clearly contrasted with hepatitis c virus (hcv) infection in the same model; indeed, hcv infection is accompanied by a profound modification of cellular gene expression, in particular of isgs. |
| PubMedID- 22666173 | Risk factors for infection with different hepatitis c virus genotypes in southern brazil. |
| PubMedID- 24073221 | Background and aims: vitamin d exerts immunomodulatory effects on the host response against infection with hepatitis c virus (hcv). |
| PubMedID- 23650587 | Chronic infection with hepatitis c virus (hcv) is a global health problem affecting a significant proportion of world’s population. |
| PubMedID- 24265237 | Also, liver steatosis can be induced by many other causes including excessive alcohol consumption, infection with genotype 3 hepatitis c virus and certain medications. |
| PubMedID- 20163377 | Background: chronic infection with hepatitis c, genotype 2/3, responds better than other genotypes to peginterferon and ribavirin treatment. |
| PubMedID- 23936821 | Chronic infection with hepatitis c virus (hcv) affects almost 200 million people worldwide, representing a leading cause of cirrhosis and anticipated liver-related death 1. |
| PubMedID- 26170396 | Background: daclatasvir is an ns5a inhibitor approved for treatment of infection due to hepatitis c virus (hcv) genotypes (gts) 1-4. |
| PubMedID- 22087188 | In developed countries, people who inject drugs (pwid) are at the greatest risk of infection with hepatitis c virus (hcv) . |
| PubMedID- 21271404 | In the multivariate analysis, low cd4 percentage, co-infection with hepatitis c or d viruses, hiv diagnosis before 1996 and hbeag positivity were independently associated with poor perceived overall health. |
| PubMedID- 20924215 | Exclusion criteria included co-infection with hepatitis c, or the human immunodeficiency virus; evidence of cirrhosis or hepatocellular carcinoma; previous exposure to any nucleoside analog that is active against hbv; use of interferon alpha within 6 months before enrollment. |
| PubMedID- 23677838 | Osteoporosis is increasingly reported in the aging hiv-positive population, and co-infection with hepatitis c virus (hcv) may further increase the risk of osteoporosis. |
| PubMedID- 25646622 | Along these lines, somewhat discouraging results have recently been reported from a phase i monotherapy trial of the hcv entry inhibitor itx-5061 given for up to 28 days in the setting of established chronic infection with the hepatitis c virus . |
| PubMedID- 21645344 | In this article we discuss several liver conditions which are directly affected by overweight and obese status, including non-alcoholic fatty liver disease, chronic infection with hepatitis c virus and post-liver transplant status. |
| PubMedID- 21531464 | The response to tlr ligation of human cd16(+)cd14(-) monocytes is weakly modulated as a consequence of persistent infection with the hepatitis c virus. |
| PubMedID- 21573126 | Recent evidence also suggests that one mechanism of hcc development upon infection with hepatitis c virus (hcv) may be through increased genomic instability following inactivation of rb . |
| PubMedID- 22814930 | Cd40l is up-regulated on lymphocytes and cd40 on hepatocytes during infection with hepatitis c virus (hcv); we investigated the role of cd40 signaling during hcv replication in hepatocytes. |
| PubMedID- 23010773 | Introduction: adverse effects appearing during combined peg-interferon and ribavirin antiviral treatment against chronic infection with the hepatitis c virus are a major cause for treatment failures and abrupt interruption. |
| PubMedID- 20080094 | Activation of natural killer cells during acute infection with hepatitis c virus. |
| PubMedID- 26401088 | Aim: to determine the prevalence of infection with hepatitis c virus (hcv) in those most at risk of advanced liver disease and to identify gaps in knowledge of hcv. |
| PubMedID- 23197230 | The exclusion criteria were co-infection with hepatitis c virus (hcv) or human immunodeficiency virus type-1, serological markers suggestive of autoimmune disease, daily intake of alcohol >50 g, recent exposure to hepatotoxic drugs, and no stored sera available. |
| PubMedID- 24463875 | Treatment of infection due to hepatitis c virus in haemodialysis. |
| PubMedID- 24081825 | Curcumin, a traditional chinese and indian treatment for many diseases, has recently been found to alter the in vitro infection processes of various viruses, including hepatitis c virus, human immunodeficiency virus, coxsackievirus, and japanese encephalitis virus. |
| PubMedID- 20929104 | Cirrhosis due to chronic infection with hepatitis c virus remains by far the most common reason for liver transplantation in north america. |
| PubMedID- 23226258 | Co-infection with hepatitis c virus (hcv) and hiv is common because these viruses share the same transmission route. |
| PubMedID- 21741004 | Background/purpose: chronic infection with the hepatitis c virus (hcv) is associated with impaired lipid metabolism. |
| PubMedID- 21449783 | Background: peginterferon-ribavirin therapy is the current standard of care for chronic infection with hepatitis c virus (hcv). |
| PubMedID- 23230035 | Purpose: the pharmacologic properties, clinical efficacy, and safety profile of the first oral protease inhibitor approved for the treatment of chronic infection with hepatitis c virus (hcv) genotype 1 are reviewed. |
| PubMedID- 26470982 | High rate of infection with hepatitis c virus genotype 4 in chad, central africa. |
| PubMedID- 20950406 | Chronic infection with the hepatitis c virus (hcv) is more prevalent than human immunodeficiency virus (hiv) infection, but more public health resources are allocated to hiv than to hcv. |
| PubMedID- 26429337 | Chronic infection with hepatitis c virus (chc) is a large public health problem, impacting an estimated three million people in the united states . |
| PubMedID- 21827653 | Co-infection with hepatitis c virus (hcv) may further complicate the assessment of iron status, as hcv infection is associated with high plasma ferritin concentrations . |
| PubMedID- 24013001 | infection with genotype 3 hepatitis c virus (hcv) is common throughout the world, however no direct-acting antiviral (daa) has been approved to treat this genotype. |
| PubMedID- 24148806 | At multivariate analysis, hepatitis b virus infection was associated with male gender, hepatitis c virus infection with drug addiction, and human immunodeficiency virus infection was associated with female gender, drug addiction, and active recruitment. |
| PubMedID- 23869873 | Background and aim: chronic infection with hepatitis c virus (hcv) decreases health-related quality of life (hrqol). |
| PubMedID- 26426687 | Persistent infection with hepatitis c virus (hcv) is associated with an increased risk of hepatocellular carcinoma (hcc). |
| PubMedID- 23338483 | infection with hepatitis c virus is an adverse prognostic factor after liver resection for early-stage hepatocellular carcinoma: implications for the management of hepatocellular carcinoma eligible for liver transplantation. |
| PubMedID- 21384510 | Re-infection with the hepatitis c virus (hcv) is an important development after liver transplantation (lt); it can lead to graft fibrosis. |
| PubMedID- 24734095 | Older age, malnutrition and infection with hepatitis c virus and human immunodeficiency virus can also have some effects on reduction of the effectiveness of hbv vaccination (18-21). |
| PubMedID- 24082889 | The inclusion criteria were as follows: 1) ultrasound showing a diffusely echogenic liver; 2) having normal or elevated alt (more than 1.5 times); 3) all the patients had negative results for serum genomic hcv rna and anti-hcv (tested at least three times before the entry to the study);4) patients exclusion criteria were all known causes of cirrhosis; for instance: alcohol abuse (> 20 g/day), infection with hepatitis c virus (plasma hcv rna and anti-hcv positive), infection with hepatitis b virus plasma hbv dna, hepatitis b surface antigen (hbsag), hepatitis b e antigen (hbeag), hepatitis b core antibody (hbcab), and hepatitis b e antibody (hbeab) positive, autoimmune hepatitis, genetic disorders, wilson's disease, drug toxicity, nash, haemochromatosis, biliary obstruction and primary biliary cirrhosis, presence of any severe systemic illness, malignancies, and positive results for anti-human immunodeficiency virus antibodies (anti-hivabs). |
| PubMedID- 22184515 | Liver dysfunction may vary from a self-limiting cholestasis to cases of cirrhosis and liver failure; however, severe liver disease rarely occurs in these patients unless other concomitant pathologies, such as infection with hepatitis c virus (hcv) or human immunodeficiency virus (hiv) are present.58,64,73 other clinical characteristics suggestive of liver failure are flapping tremor and spider nevi. |
| PubMedID- 23703797 | Vitamin d is an important immune modulator that plays an emerging role in inflammatory and metabolic liver diseases, including infection with hepatitis c virus (hcv). |
| PubMedID- 25285757 | Chronic infection with hepatitis c virus (hcv) may lead to b cell activation and transformation into non-hodgkin lymphoma (nhl). |
| PubMedID- 21743211 | infection with hepatitis c virus (hcv) is increasing all over the world, especially among hemodialysis patients. |