eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hepatitis c |
| Symptom | |infection |
| Sentences | 461 |
| PubMedID- 22848445 | Chronic infection with the hepatitis c virus (hcv) affects an estimated 2–3% of the world's population and is a leading cause of cirrhosis and hepatocellular carcinoma 1. |
| PubMedID- 23499158 | Background: protease inhibitors have improved treatment of infection with hepatitis c virus (hcv), but dosing, a low barrier to resistance, drug interactions, and side-effects restrict their use. |
| PubMedID- 22107817 | Background: some, but not all, studies have demonstrated that dual infection with hepatitis c virus (hcv) and hiv has worse effects on cognition than infection with hiv alone. |
| PubMedID- 25893197 | Chronic infection with hepatitis c virus negatively regulates both the innate and adaptive arms of the immune system. |
| PubMedID- 22129112 | Co-infection with hepatitis c occurred in more than 10% of cases, which can also enhance transmission of hiv . |
| PubMedID- 22817275 | Current estimates of the residual risks of transfusion-transmitted infection with hiv, hepatitis c virus (hcv), and hbv in korea are drawn from old studies that only examined donors for short periods of time 1. |
| PubMedID- 22190521 | infection with hepatitis c virus (hcv) is one of the major global health problems, approximately 170 million people are infected worldwide. |
| PubMedID- 20823335 | We employed this clustering feature to define knockdowns which harm viral infection efficiency of human hepatitis c virus. |
| PubMedID- 21874838 | The rise of infection with hepatitis c virus worldwide and the lack of effective treatment for this infection has led to a rise in the incidence of hepatocellular carcinoma (hcc). |
| PubMedID- 24797101 | High rates of sexually transmitted infection and reinfection with hepatitis c virus (hcv) have recently been reported in human immunodeficiency virus (hiv)-infected men who have sex with men and reinfection has also been described in monoinfected injecting drug users. |
| PubMedID- 26058595 | In japan, most european countries, and america, approximately 60% of hcc cases are attributed to chronic infection with hepatitis c virus (hcv) 3. |
| PubMedID- 21576430 | Chronic infection with hepatitis c virus (hcv) is a major global health burden and is associated with an increased risk of liver cirrhosis and hepatocellular carcinoma. |
| PubMedID- 21473719 | Upon infection with hepatitis c virus (hcv), only few patients spontaneously clear the virus, while most patients develop chronic hcv infection. |
| PubMedID- 25979354 | infection of hepatocytes with hepatitis c virus led to the incorporation and export of viral genomic and sub-genomic rna sequences in evs. |
| PubMedID- 25820703 | Background: chronic infection with hepatitis c virus (hcv) genotype 2 or 3 can be treated with sofosbuvir without interferon. |
| PubMedID- 26512676 | Interferon (ifn) and cellular immune response evoked in rna-pattern sensing during infection with hepatitis c virus (hcv). |
| PubMedID- 26374068 | infection with hepatitis c, or if that fails, liver transplantation. |
| PubMedID- 21407274 | The prevalence of chronic infection with the hepatitis c virus (hcv) in patients with chronic kidney disease is higher than in the general population. |
| PubMedID- 21609471 | Injection drug users (idus) are at high risk of infection with hiv, hepatitis c (hcv) and other blood-borne pathogens transmitted by sharing syringes and other injection equipment. |
| PubMedID- 24717818 | An estimated 3.2 million persons in the united states have chronic infection with hepatitis c virus (hcv). |
| PubMedID- 22830036 | Chronic infection with hepatitis c virus (hcv) is an independent risk factor for developing type 2 diabetes mellitus (dm) . |
| PubMedID- 23872239 | Chronic infection with hepatitis c virus (hcv) is a major global health problem; there are approximately 120 to 130 million chronic infections worldwide. |
| PubMedID- 25837807 | Initial infection with hepatitis c virus (hcv) is characterized by detection of virus in blood within 2–14 days of exposure, increases in hepatic transaminases, and appearance of detectable hcv-specific antibodies (anti-hcv) within 30–60 days of exposure . |
| PubMedID- 21477324 | Chronic infection with hepatitis c virus (hcv) is a major and growing public health problem, which could easily lead to chronic liver disease, cirrhosis and even hepatocellular carcinoma 1. |
| PubMedID- 22039483 | For example, chronic infection with hepatitis c virus (hcv) results from reduction of the dimerization of mitochondrial antiviral signaling protein (mavs) by hcv nonstructural (ns) protein ns3/4a protease to levels that are too low to mount strong enough antiviral immune responses . |
| PubMedID- 24106239 | infection with hepatitis c virus (hcv) is frequent in parts of africa and asia, with europe and america considered as regions with a lower prevalence of chronic hepatitis c (0.5–2%) (nature outlook, 2011). |
| PubMedID- 20735940 | §co-infection with hepatitis c virus and hepatitis b virus. |
| PubMedID- 26189518 | Since the majority of hepatocellular carcinoma (hcc) arises from a background of chronic liver diseases caused by infection with hepatitis c virus (hcv) and hepatitis b virus (hbv), chemoprevention targeting patients at high risk of hcc is feasible. |
| PubMedID- 22826750 | hepatitis a virus is a benign and asymptomatic disease, however when it happens in super infection with hepatitis c, it leads to more severe consequences such as liver diseases, acute liver failure and even fulminant hepatitis or death. |
| PubMedID- 24782260 | In the era of effective treatment for human immunodeficiency virus (hiv) infection, coinfection with hepatitis c virus (hcv) is an important cause of morbidity and mortality. |
| PubMedID- 22534629 | Background: chronic infection with hepatitis c virus (hcv) is associated with failures of t-cell-mediated immune clearance and with abnormal b-cell growth and activation. |
| PubMedID- 21299490 | In the absence of evidence of infection with the hepatitis c virus (hcv), detecting the immunological disorder of mixed cryoglobulinaemia is a challenge. |
| PubMedID- 24984340 | Recently approved direct-acting antiviral agents (daa) for the treatment of chronic infection with hepatitis c virus (hcv) genotype 1, protease inhibitors (pi) boceprevir and telaprevir, have substantially increased the rates of sustained virologic response in the treatment of naive and experienced patients. |
| PubMedID- 22087137 | infection with hepatitis c (hcv) and/or hepatitis b (hbv) virus and elevated alcohol consumption are leading risk factors for hcc, accounting for ~90% of cases (bibmm). |
| PubMedID- 24251062 | Significant comorbidities include infection with hepatitis c virus (grade 1, stage 0). |
| PubMedID- 22792259 | Chronic infection with hepatitis c virus (hcv) is considered a major risk for chronic liver failure. |
| PubMedID- 26209383 | We report on the first well-tolerated and successful use of sofosbuvir-based therapy in a patient in whom chronic infection with hepatitis c had preceded the development of b-cell non-hodgkin's lymphoma. |
| PubMedID- 26159282 | Background: opportunities to treat infection with hepatitis c virus (hcv) are evolving rapidly. |
| PubMedID- 21886060 | Background: hepatitis secondary to infection with the hepatitis c virus (hcv) is one of the most common causes of viral hepatitis worldwide. |
| PubMedID- 23393570 | Introduction: co-infection with hepatitis c (hcv) and hiv is common and hiv accelerates hepatic disease progression due to hcv. |
| PubMedID- 20974315 | Background: the standard treatments for chronic infection with the hepatitis c virus (hcv) are peginterferon alpha-2a or alpha-2b plus ribavirin, but it remains unclear if one has a better efficacy and safety profile. |
| PubMedID- 21681720 | Prevalence of extra-hepatic manifestations in infection with hepatitis c virus: study of 140 cases. |
| PubMedID- 25544499 | infection with hepatitis c virus (hcv), a major viral cause of chronic liver disease, frequently progresses to steatosis and cirrhosis, which can lead to hepatocellular carcinoma. |
| PubMedID- 20516810 | infection with hepatitis c virus (hcv) can be associated with demyelinating polyneuropathy that may be responsive to immunomodulatory therapy. |
| PubMedID- 23285778 | Introduction: infection with hepatitis c virus is a serious worldwide health problem. |
| PubMedID- 22921476 | Baseline infection with hepatitis c or b was the only significant predictor of moving from low to elevated transaminase levels; 9 bup and 15 met participants showed extreme liver test elevations and were more likely than those without extreme elevations to have seroconverted to both hepatitis b and c during the study, or to use illicit drugs during the first 8 weeks of treatment. |
| PubMedID- 22355327 | Overall these results suggest that infection with the hepatitis c virus is associated with increase of soluble cd81. |
| PubMedID- 20156300 | Persistent infection with hepatitis c virus (hcv) is a major risk toward development of hepatocellular carcinoma (hcc). |
| PubMedID- 25880556 | This mirna has also been found to be upregulated in hepatoma cells upon infection with the hepatitis c virus . |
| PubMedID- 23912098 | The presence of neuropathy and infection with hepatitis c were significant differences between the frail and non-frail patients. |