eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | hepatitis c |
| Symptom | |infection |
| Sentences | 461 |
| PubMedID- 23548687 | Viral infection with hepatitis c and hepatitis b was present in 13.7 and 3.6% of patients, respectively. |
| PubMedID- 21598151 | Vignettes were all combinations of five factors: level of bad news (infection with hepatitis c, cirrhosis of the liver, or liver cancer); request or not to the patient to come with spouse or partner; attempt or not by the physician to find out the patient's expectations about the test results; presence or absence of emotional supportiveness; and provision or not of complete and understandable information. |
| PubMedID- 20208985 | Chronic infection with the hepatitis c virus (chc) in the united states is reported to have peaked at 3.6 million americans affected; however, the number of individuals with advanced fibrosis is projected to continue to rise until the year 2020 1. |
| PubMedID- 22863785 | T cell immunoglobulin and mucin domain-containing 3 (tim-3) is an inhibitory receptor that is expressed on exhausted t cells during infection with hiv-1 and hepatitis c virus. |
| PubMedID- 23913866 | Kinetic differences in the induction of interferon stimulated genes by interferon-alpha and interleukin 28b are altered by infection with hepatitis c virus. |
| PubMedID- 21546048 | The d/d genotype may increase the susceptibility to infection with hepatitis c. |
| PubMedID- 22486282 | In industrialised countries, injecting drug use is currently the most important risk factor for infection with hepatitis c, resulting in high prevalence of hepatitis c among injecting drug users (idus). |
| PubMedID- 21981772 | Aids was indicated as a possible infection by 60.3% of freshmen, hepatitis c by 38.2%, tetanus by 34.3% and hepatitis b by 33.7% of the sample. |
| PubMedID- 25624998 | Although liver resection and liver transplantation offer the chance of a cure for hcc, adequate management of co-existing infection with hepatitis c virus (hcv) is important to enable better long-term outcomes after surgery for hcv-related hcc. |
| PubMedID- 22537438 | Recently developed drugs and innovative strategies for the treatment of chronic infection with genotype 1 hepatitis c virus (hcv) have become the standard of care. |
| PubMedID- 22984515 | Overwhelming lines of epidemiological evidence have indicated that persistent infection with hepatitis c virus (hcv) is a major risk for the development of hepatocellular carcinoma (hcc). |
| PubMedID- 26357633 | Chronic infection with hepatitis c virus (hcv) carries a significant global health burden in both children and adults, with approximately 3% of the world's population infected. |
| PubMedID- 22421553 | Background: unsafe injecting practices put injecting drug users (idus) at repeat exposure to infection with the hepatitis c virus (hcv). |
| PubMedID- 24925642 | The aim of the present study was to measure the influence of chronic infection with viral hepatitis c (chc) genotype 1 and 4 on serum levels of activin-a, activin-b and follistatin, and to determine their correlations with viral load, liver damage, interleukin-6 (il-6) and tumour necrosis factor (tnf)-alpha. |
| PubMedID- 23101217 | Results: a total of 1,633 hepatitis b cases, including 38 cases of co-infection with hepatitis c (hcv) was reported in 2010. |
| PubMedID- 20002561 | infection with the hepatitis c virus commonly occurs in patient groups who have difficulty accessing conventional medical care, reducing their chance of successful antiviral therapy. |
| PubMedID- 25766746 | infection with hepatitis c virus (hcv) results in chronic and progressive liver disease. |
| PubMedID- 24296877 | To investigate whether cygb can be utilized to distinguish hepatic stellate cells from myofibroblasts in normal and fibrotic human liver, human liver tissues damaged by infection with hepatitis c virus (hcv) and at different stages of fibrosis were obtained by liver biopsy. |
| PubMedID- 21326840 | Chronic infection with hepatitis c virus is estimated to affect almost 4 million people in the usa, 5 million in europe, and 170 million worldwide 1. |
| PubMedID- 22213804 | infection with the hepatitis c virus is a major health burden worldwide (alter and seeff, 2000; lauer and walker, 2001). |
| PubMedID- 25375324 | Using sirna gene silencing, we found that proteins known to be important for late endosomal maturation and endosome-lysosome fusion profoundly promote infection of cells with mouse hepatitis coronavirus (mhv). |
| PubMedID- 23315914 | Chronic infection with the hepatitis c virus (hcv) is a leading cause of global morbidity and mortality. |
| PubMedID- 23039099 | Background: there has been limited study on the effect of infection with different hepatitis c virus (hcv) genotypes on the risk of hepatocellular carcinoma (hcc) in hepatitis b virus (hbv) endemic regions of asia. |
| PubMedID- 26519873 | Background: recurrent infection with the hepatitis c virus (hcv) after liver transplantation is associated with decreased graft and patient survival. |
| PubMedID- 23300497 | Occult hepatitis b virus infection in patients with chronic hepatitis c treated with antiviral therapy. |
| PubMedID- 23327541 | infection with hepatitis c virus (hcv) is associated with significant morbidity, mortality, and economic burden. |
| PubMedID- 22878466 | Mental health problems frequently occur in chronic infection with the hepatitis c virus (hcv) and during antiviral treatment with pegylated interferon-alpha (pegifnalpha) and ribavirin. |
| PubMedID- 22368684 | Background: co-infection with hepatitis c virus (hcv) and/or human immunodeficiency virus (hiv) in patients with chronic hepatitis b virus (hbv) infection can alter the course of the disease. |
| PubMedID- 22711689 | Persistent infection with hepatitis c virus (hcv) can lead to chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. |
| PubMedID- 23741761 | Susceptibility factors (including excess hepatic iron, hfe mutations, alcohol consumption, infection with hepatitis c and/or human immunodeficiency viruses, oral estrogen use, smoking, and hepatotoxins e.g., hexachlorobenzene) play a significant role in development of clinical manifestations. |
| PubMedID- 26357610 | Chronic infection with hepatitis c virus (hcv) is estimated to affect approximately 3% of the world's population and cause 350,000 deaths each year. |
| PubMedID- 21167831 | By multivariate regression analysis, independent significant predictors for women to not achieve an svr were early menopause (odds ratio or, 8.055; 95% confidence interval ci, 1.834-25.350), levels of gamma-glutamyl transpeptidase (or, 2.165; 95% ci, 1.364-3.436), infection with hepatitis c virus genotype 1 or 4 (or, 3.861; 95% ci, 2.433-6.134), and cholesterol levels (or, 0.985; 95% ci, 0.971-0.998). |
| PubMedID- 22155365 | High levels of autophagy occur during infection of cells with hepatitis c virus (hcv), but the clinical relevance of this process is not clear. |
| PubMedID- 25081062 | Background: chronic infection with hepatitis c virus (hcv) is a risk factor for liver diseases such as fibrosis, cirrhosis and hepatocellular carcinoma. |
| PubMedID- 26347518 | Background/aims: the immunoregulatory molecules programmed death 1 (pd-1) and cytotoxic t lymphocyte-associated antigen 4 (ctla-4) are associated with the dysfunction of antiviral effector t-cells, which leads to t-cell exhaustion and persistent viral infection in patients with chronic hepatitis c and chronic hepatitis b. |
| PubMedID- 22336134 | Paradoxical expression of il-28b mrna in peripheral blood in human t-cell leukemia virus type-1 mono-infection and co-infection with hepatitis c virus. |
| PubMedID- 24040725 | Results: a total of 1,583 hepatitis b cases, including 30 cases of co-infection with hepatitis c (hcv) was reported in 2011. |
| PubMedID- 26225247 | Chronic infection with hepatitis c virus (hcv) affects about 170 million people worldwide and is a major cause of liver complications. |
| PubMedID- 23682439 | Hiv clinical stage 3 or 4, co-infection with tuberculosis and hepatitis c infection and a cd4+ t cell count of <50 cells/microl were risk factors for ocular disease in hiv/aids patients. |
| PubMedID- 23954997 | Exclusion criteria were as follows: a) receiving interferon (ifn) or nucleoside analogues antiviral therapy in the last 2 years; b) a history of fever in the past 6 months; c) clinical and/or biochemical signs of chronic active hepatitis (spider angiomas, liver palm, splenomegaly, decreased serum albumin, or portal hypertension); d) co-infection with hepatitis c virus, hepatitis d virus or human immunodeficiency virus; e) coexisting serious medical or psychiatric illness; f) organ or bone marrow transplantation; g) recent treatment with systemic corticosteroids, immunosuppressants, or chemotherapeutic agents; h) a serum alpha-fetoprotein levels over 50 ng/ml. |
| PubMedID- 25905096 | Even if confounding factors, such as drug use and co-infection with hepatitis c virus (hcv) have been reported (18), more than 80% of pah cases in the hiv population are directly related to hiv and/or its treatment (19, 20). |
| PubMedID- 24983019 | As rhode island's only needle exchange program, encore (education, needle exchange, counseling, outreach, and referrals) serves a wide range of clients infected or at risk for infection with hepatitis c virus (hcv). |
| PubMedID- 22496645 | Physiologically relevant cell-culture models for infection with hepatitis c virus (hcv) are scarce, and infection by viruses derived from patient serum has been inefficient. |
| PubMedID- 24631092 | hepatitis c virus (hcv) leads to chronic infection in the majority of infected patients presumably due to failure or inefficiency of the immune responses generated. |
| PubMedID- 25579804 | Continuous hepatic inflammation as a result of chronic infection with the hepatitis c virus may lead to the development of fibrosis and eventually cirrhosis. |
| PubMedID- 21526182 | Meanwhile, dqa1*0103 appears to provide protection against chronic active infection with hepatitis c virus . |
| PubMedID- 22533731 | Background: co-infection with hepatitis c (hcv) is very common in human immunodeficiency virus 1 (hiv-1) infected patients. |
| PubMedID- 21722330 | Cv may occur as primary 'essential' vasculitis or - and much more frequently - as secondary vasculitis, mostly due to infection with the hepatitis c virus. |
| PubMedID- 24732775 | Design: a population-based cohort study including all hiv-infected individuals born in denmark and not reporting intravenous (i.v.) drug abuse as a route of hiv infection or diagnosed with hepatitis c infection (n = 2799) and 22,369 individually matched persons from the background population. |
| PubMedID- 26034769 | Human immunodeficiency virus coinfection in the context of chronic hepatitis c virus (hcv) infection accelerates progression to clinical liver outcomes, at least among hemophiliacs , although the mechanisms have yet to be fully characterized. |