eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | portal hypertension |
| Symptom | |cirrhosis |
| Sentences | 129 |
| PubMedID- 25457205 | Background & aims: inflammation, collagen deposition and tissue remodelling are involved in the pathogenesis and complications of cirrhosis with portal hypertension. |
| PubMedID- 22848732 | Diagnosis of cfld is challenging because its clinical presentation ranges from simple steatosis to multi-lobular biliary cirrhosis with portal hypertension . |
| PubMedID- 24171010 | Table 1 summarizes the hepatobiliary clinical findings in cf.the evolution of cfld is usually slow and progressive: only about 10% of patients affected by cf and cirrhosis with portal hypertension progress to liver synthetic failure generally after pediatric age (14, 43, 44). |
| PubMedID- 22333168 | Conclusion: the arb is effective in reducing portal hypertension in patients with cirrhosis, which is similar to propranolol. |
| PubMedID- 20113491 | In addition, although splenomegaly should be expected in severe cirrhosis with portal hypertension, there were no statistical differences in splenic area among the three groups analyzed, indicating that splenomegaly was not a prominent feature in our study of cirrhotic rats. |
| PubMedID- 26064107 | They can detect advanced cirrhosis with signs of portal hypertension (enlarged spleen and portal vein, and collateral venous circulation), but not fibrosis of lesser stages . |
| PubMedID- 25374709 | In view of a normal serology, the patient's diagnosis was alcohol-related cirrhosis with portal hypertension with portal colopathy with massive lower gi bleed. |
| PubMedID- 20616408 | cirrhosis leads to portal hypertension which induces portosystemic collaterals, allowing gut-derived humoral substances to directly enter the systemic circulation without detoxification by the liver. |
| PubMedID- 23251280 | The patients all suffered from hepatic cirrhosis decompensation with portal hypertension. |
| PubMedID- 22697282 | The performed magnetic resonance imaging examination confirmed the diagnosis of cirrhosis associated with portal hypertension and detected a vascular left transdiaphragmatic hernia. |
| PubMedID- 22593813 | A minor adverse event occurred in a 56 year old man hospitalized for gastrointestinal bleeding, cirrhosis with portal hypertension, thrombocytopenia and coagulation abnormalities. |
| PubMedID- 22121492 | It is this author's opinion that 12 cm should be the threshold to diagnose splenomegaly and raise suspicion of cirrhosis with portal hypertension. |
| PubMedID- 21806953 | Background & aims: cirrhosis patients with symptomatic portal hypertension might be effectively treated with a transjugular intrahepatic portosystemic shunt stent (tips). |
| PubMedID- 26422126 | Development of hyperdynamic circulation and response to beta-blockers in compensated cirrhosis with portal hypertension. |
| PubMedID- 25037870 | Hcc patients seemed to suffer from less severe or shorter duration of portal hypertension compared with child-pugh class-matched cirrhosis patients. |
| PubMedID- 24493093 | From 2,879 cases that underwent ce, 45 cirrhosis patients with portal hypertension (ph) were enrolled and divided into phe (n = 18) and non-phe (n = 27) groups. |
| PubMedID- 24719556 | Background: oxidative stress is involved in the hypocontractility of visceral artery to vasoconstrictors and formation of hyperdynamic circulation in cirrhosis with portal hypertension. |
| PubMedID- 25338529 | In the early stages of liver fibrosis, low ho-1 induction may exert a protective action (45), but in the end stages of cirrhosis with portal hypertension, excessive ho-1 expression deteriorates liver function and aggravates liver cirrhosis (43,46,47). |
| PubMedID- 20968204 | The kidney in cirrhosis with portal hypertension. |
| PubMedID- 25848469 | This review describes the recent developments in the pathobiology of endothelial dysfunction (ed) in the context of cirrhosis with portal hypertension and defines novel strategies and potential targets for therapy. |
| PubMedID- 23293387 | Characteristically, there is worsening cholestasis, fibrosis and cirrhosis which lead to portal hypertension and a decrease in synthetic function. |
| PubMedID- 20562900 | Hepatic fibrosis and its endstage cirrhosis, with life-threatening complications of portal hypertension and liver failure, have become major public health problems1. |
| PubMedID- 22086533 | However, she developed hepatic cirrhosis with portal hypertension. |
| PubMedID- 20339175 | Levels of globulins significantly increased in cirrhosis with portal hypertension (p<0.001). |
| PubMedID- 24940392 | In addition, cirrhosis leads to portal hypertension and hyperdynamic circulation that can have widespread effects in the body (15). |
| PubMedID- 22811587 | Hepatic manifestations were first described by klatskin and yesner in 1950 and include granulomatous hepatitis, cholestasis, cirrhosis, portal fibrosis leading to presinusoidal portal hypertension, budd-chiari syndrome, adult ductopenia-like syndrome, and rarely chronic granulomatous sclerosing cholangitis with ductal strictures . |
| PubMedID- 23329943 | The diagnosis of cirrhosis with portal hypertension was based on a combination of clinical data such as jaundice, ascites, muscle wasting, cutaneous spider angiomas, ecchymosis, palmar erythema and flapping tremors; laboratory data such as decreased serum albumin and prolonged prothrombin time; and us findings such as coarsened echo texture and irregular liver surface. |
| PubMedID- 26406236 | Background & aims: although in cirrhosis with portal hypertension levels of the vasoconstrictor angiotensin ii are increased, this is accompanied by increased production of angiotensin (ang)-(1-7), the endogenous ligand of the mas receptor (masr), which blunts hepatic fibrosis and decreases hepatic vascular resistance. |
| PubMedID- 22248963 | Caput medusae and palmar erythema are cardinal signs in cirrhosis of liver with portal hypertension. |