eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | herpes simplex |
| Symptom | |infection |
| Sentences | 147 |
| PubMedID- 22384166 | An increased permissiveness for infection with herpes simplex virus during the first 48 hours of infection has been demonstrated in ebv-converted, previously negative burkitt's lymphoma derived cell lines . |
| PubMedID- 21176214 | Genital herpes results from infection with herpes simplex virus type 2 (hsv-2), or less commonly type 1 (hsv-1). |
| PubMedID- 24637385 | Here we reveal that upon skin infection with herpes simplex virus, migratory cd103+ dcs from draining lymph nodes were more potent at inducing th17 cytokine production by cd4+ t cells than cd8+ dcs. |
| PubMedID- 22363358 | infection with herpes simplex virus (a dna virus) is the most prevalent infective disease of human after viral respiratory infections. |
| PubMedID- 26086165 | Primary genital infection with herpes simplex virus types 1 and 2 can be manifested by a severe clinical picture, involving the vesicular skin and mucosal changes and ulcerative lesions of the vulva, vagina, and cervix in women and in the genital region in men. |
| PubMedID- 23213313 | Glutamine and leucine provide enhanced protective immunity against mucosal infection with herpes simplex virus type 1. |
| PubMedID- 25006480 | Genital infection with herpes simplex virus types 1 and 2 in women from natal, brazil. |
| PubMedID- 24400006 | Interestingly, ddx60 can also bind dsdna, and was shown to play role in ifn-i expression after infection with herpes simplex virus-1, a dna virus. |
| PubMedID- 25497088 | We show here that infection with herpes simplex virus 1 (hsv-1) results in chromosomal structural aberrations at telomeres and the accumulation of telomere dysfunction-induced dna damage foci (tifs). |
| PubMedID- 23261465 | After infection with herpes simplex virus type 1 (hsv-1), latent infection persists for life in the trigeminal ganglion and reactivation results in an outbreak of cold sores around the mouth. |
| PubMedID- 21498376 | Background: genital infection with herpes simplex virus 2 (hsv-2) is linked to an increased risk of infection with human immunodeficiency virus (hiv) in areas such as sub-saharan africa. |
| PubMedID- 20688399 | Intravaginal infection with herpes simplex virus type-2 (hsv-2) generates a functional effector memory t cell population that persists in the murine genital tract. |
| PubMedID- 22312431 | Further studies revealed that sting-knockout mice are susceptible to lethal infection with herpes simplex virus 1 and vesicular stomatitis virus, demonstrating the critical role of sting in facilitating immune responses to viral pathogens . |
| PubMedID- 20674092 | Epidemiological and experimental findings suggest that chronic infection with herpes simplex virus type 1 (hsv-1) may be a risk factor for alzheimer's disease (ad), but the molecular mechanisms underlying this association have not been fully identified. |
| PubMedID- 23030500 | Involvement of viral glycoprotein gc-1 in expression of the selectin ligand sialyl-lewis x induced after infection with herpes simplex virus type 1. |
| PubMedID- 22811539 | Ocular infection with herpes simplex virus 1 (hsv-1) results in a chronic immunoinflamammtory reaction in the cornea, which is primarily orchestrated by cd4(+) t cells. |
| PubMedID- 24114149 | For example, in infection with herpes simplex virus type 1 (hsv-1) induction of cd4+cd25+foxp3+ treg cells was shown to be associated with a reduction of immune pathology and better clinical outcome . |
| PubMedID- 22659469 | Role of mir-132 in angiogenesis after ocular infection with herpes simplex virus. |
| PubMedID- 24736562 | In murine corneal infection with herpes simplex virus, depletion of nk cells leads to loss of viral control . |
| PubMedID- 21732959 | Kaposi's varicelliform eruption is a widespread infection due to herpes simplex virus (hsv) types 1 and 2, coxsackievirus a16 or vaccinia virus, occurring in a preexisting dermatosis; only one case has been reported in prp. |
| PubMedID- 24982675 | This study was undertaken to determine the prevalence of cervical infection with herpes simplex virus (hsv), chlamydia trachomatis (ct), and neisseria gonorrhoeae (ng) among married women referring to iranian hospital, dubai, uae. |
| PubMedID- 24587916 | Have also reported protective effect of lf in preventing weight loss during infection with herpes simplex virus type 1 in mice. |
| PubMedID- 22057015 | The authors also examined the association between depression and infection with herpes simplex virus type 2 (hsv-2), a biological marker of risky sexual behaviours. |
| PubMedID- 23638732 | Intravaginal (ivag) infection of mice with herpes simplex virus type 2 (hsv-2) causes genital tissue damage, quickly followed by development of fatal encephalopathy. |
| PubMedID- 23414251 | Severe cutaneous necrosis due to mixed infection with herpes simplex virus and fungi in an unrelated cord blood stem cell transplantation recipient. |
| PubMedID- 20138011 | Neither infection with herpes simplex virus (labial infection in all) nor infection with varicella zoster virus were significantly associated with dexamethasone treatment. |
| PubMedID- 26358082 | For example, infection with herpes simplex virus, paramyxovirus, influenza virus, hepatitis virus, or hiv, oxidative stress and free radical generation contribute to the pathogenesis of disease . |
| PubMedID- 21768868 | Herpes esophagitis due to infection with herpes simplex virus typically occurs in immunocompromised patients such as those with human immunodeficiency virus, malignancy, and those undergoing immunosuppressive therapy. |
| PubMedID- 24464523 | Coinfection with herpes simplex virus type 2 (hsv-2) is common in hiv infection, and has been associated with increased plasma and genital tract hiv rna levels,12 increased immune activation3 and some measures of accelerated hiv disease progression45 among highly active antiretroviral therapy (haart)-untreated individuals. |
| PubMedID- 20458339 | Here, we have examined the kinetics of these events, measuring the period over which naive precursors are recruited into the primary t cell response after cutaneous infection with herpes simplex virus type 1 (hsv-1). |
| PubMedID- 23386436 | infection of cells with alphaherpesviruses (herpes simplex virus hsv and varicella-zoster virus vzv) results in the deposition of nucleosomes bearing repressive histone h3k9 methylation on the viral genome. |
| PubMedID- 22496691 | infection with herpes simplex virus type 1 (hsv-1) provoked autophagy under conditions that inhibited viral gene expression. |
| PubMedID- 23184983 | infection with herpes simplex virus type 1 (hsv-1) and hsv-2 is initiated by viral glycoprotein d (gd) binding to a receptor on the host cell. |
| PubMedID- 24659245 | For example, centromeres damaged by infection with herpes simplex virus accumulate coilin (sabra et al., 2013; morency et al., 2007) and coilin associates with specific rna and dna sequences in the cell (broome and hebert, 2013). |
| PubMedID- 23454799 | infection with herpes simplex virus type 2 (hsv-2) can result in lesions in reproductive organs, along with long-term latency. |
| PubMedID- 23989956 | Cgas(-/-) mice were more susceptible to lethal infection with herpes simplex virus 1 (hsv1) than wild-type mice. |
| PubMedID- 23077614 | We show that co-infection with herpes simplex virus 1 or human cytomegalovirus also induces chlamydial persistence by a similar mechanism suggesting that chlamydia -human herpes virus co-infections are evolutionary shaped interactions with a thus far unrecognized broad significance. |
| PubMedID- 21173243 | Here, we examined the importance of monocytes in primary mucosal infection with herpes simplex virus 2 (hsv-2), and demonstrate that monocyte-derived apcs are required to elicit ifn-gamma secretion from effector th1 cells to mediate antiviral protection. |
| PubMedID- 26369288 | Background: erythema multiforme major (emm) is an inflammatory disease affecting skin and mucosae, often triggered by infection with herpes simplex virus. |
| PubMedID- 24347829 | Other common complications range from those affecting the musculoskeletal system (osteoporosis, aseptic bone necrosis, and myopathy), gastrointestinal system (ulcers and pancreatitis), endocrine (hyperglycemia and cushinoid features), infectious, (delayed wound healing, secondary infection, and reactivation of latent herpes simplex or tuberculosis), or even psychosis. |
| PubMedID- PMC4569616 | Ocular infection of mice with herpes simplex virus (hsv) causes induction of certain chemical changes related with the production of cytokine and chemokine (biswas and rouse 2005). |
| PubMedID- 22275910 | Interestingly, they show a similar function for hsa-mir-132 during infection of monocytes with herpes simplex virus-1 (hsv-1) and human cytomegalovirus (hcmv). |
| PubMedID- 24068938 | Reactivation events as well as primary infections are also associated with herpes simplex encephalitis (hse), a rare but life threatening consequence of infection of the central nervous system (cns) 5. |
| PubMedID- 24496543 | Diagnosis of neonatal infection with herpes simplex virus. |
| PubMedID- 23956763 | The cornea infection with herpes simplex virus (hsv) 1 leads to sk, a blinding immune-inflammatory lesion of the eye. |
| PubMedID- 23877375 | It is unknown if latent infection with another herpesvirus, herpes simplex virus 1 (hsv-1), also plays a role in shaping the lymphocyte response to exercise. |
| PubMedID- 21471229 | Corneal neovascularization represents a key step in the blinding inflammatory stromal keratitis (sk) lesion caused by ocular infection with herpes simplex virus (hsv). |