eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | portal hypertension |
| Symptom | |cirrhosis |
| Sentences | 129 |
| PubMedID- 20653965 | Patent paraumbilical and abdominal subcutaneous veins are found frequently as collaterals in patients due to portal hypertension, mainly associated with liver cirrhosis . |
| PubMedID- 25393320 | Complications of portal hypertension were significantly associated with cirrhosis (p<0.001) rather than with the severity of pvt and presence of cavernoma. |
| PubMedID- 21904911 | In contrast, animals from group 4 (pvs + taa) showed well-developed micronodular and macronodular cirrhosis, associated with significant portal hypertension and hypersplenism. |
| PubMedID- 24274743 | Long-term intoxication using inhalation is the standard method for the induction of cirrhosis with portal hypertension. |
| PubMedID- 21831314 | Sixty-seven patients were not enrolled in the study for the following reasons: (1)cirrhosis and evidence of portal hypertension (n = 17); (2) declined staging procedures and preferred to wait for new hcv therapies (n = 15); (3) omission of survey completion during early months on study implementation (n = 13); (4) declined any medical treatment or evaluation (n = 9); (5) hcv antibody positive and hcv rna negative and did not need hcv therapy (n = 7); and (6) transferring care to a different city and clinical staging could not be completed (n = 6). |
| PubMedID- 20814511 | cirrhosis of liver with portal hypertension is associated with high risk for any surgical intervention. |
| PubMedID- 24436365 | Main outcome measurements: (1) incidence of cholestasis, (2) identification of risk factors for cholestasis, (3) association between the presence of cholestasis and mi and the development of clinically significant cf-associated liver disease (cfld) defined as multilobular cirrhosis with portal hypertension. |
| PubMedID- 23755897 | Propranolol treatment of portal hypertension in cirrhosis patients is better the higher the untreated pressure: a single-centre prospective experience. |
| PubMedID- 25709491 | It has been identified as one of the leading causes of mortality, with close to 50,000 deaths attributed to it per year in the united states.1 the major morbidity from cirrhosis is due to portal hypertension, with formation of venous collaterals and marked circulatory as well as vascular abnormalities. |
| PubMedID- 25969457 | Varices are known to develop in patients having cirrhosis with portal hypertension. |
| PubMedID- 22334252 | Development of ascites in compensated cirrhosis with severe portal hypertension treated with beta-blockers. |
| PubMedID- 25655526 | cirrhosis in pregnancy with concomitant portal hypertension or esophageal varices is rare. |
| PubMedID- 23997080 | An evaluation revealed hepatic cirrhosis with portal hypertension, secondary to chronic budd-chiari syndrome. |
| PubMedID- 25256370 | Background: decreased antithrombin iii (atiii) activity and large splenic vein diameter (svd) are risk factors for portal vein thrombosis (pvt) after splenectomy in liver cirrhosis with portal hypertension. |
| PubMedID- 24889902 | Phg, by definition, requires the presence of portal hypertension, with or without cirrhosis, whereas gave requires neither cirrhosis nor portal hypertension. |
| PubMedID- 25812120 | In some patients liver fibrosis leads to liver cirrhosis with portal hypertension, hepatocellular dysfunction and increased risk of hepatocellular carcinoma . |
| PubMedID- 23559324 | Olt was performed at the age of 7 years, due to liver cirrhosis with portal hypertension, in the absence of neurological lesions and an almost-normal brain mri. |
| PubMedID- 25356325 | Resultant complications included compensated cirrhosis with portal hypertension, oesophageal varices and a previous episode of culture-negative sbp. |
| PubMedID- 25848466 | The treatment of cirrhosis-induced portal hypertension in children and adolescents is mostly based on methods developed for adults. |
| PubMedID- 21843735 | Patients with recurrent complications or cirrhosis may die because of recurrent infection, portal hypertension, liver failure, or cholangiocarcinoma. |
| PubMedID- 21213113 | Background: in patients with cirrhosis the onset of clinically significant portal hypertension (csph; i.e., hepatic venous pressure gradient (hvpg) >/= 10 mmhg) is associated with an increased risk of complications. |
| PubMedID- 26516439 | The american association for the study of liver diseases (aasld) and the european association for the study of the liver (easl) have established guidelines that indicate that liver cirrhosis with portal hypertension is a relative contraindication for hepatic resection because of the high risk liver failure after the operation (14–17). |
| PubMedID- 21103219 | Psc is characterized by progressive periductal obliterating fibrosis and strictures in the intrahepatic and extrahepatic bile ducts and usually follows a progressive course leading to cirrhosis with complications of portal hypertension and end-stage liver failure 1. |
| PubMedID- 24350068 | Liver cirrhosis causes 90% of portal hypertension in the western world, which leads to the development of porto-systemic collaterals, this in turn triggers the formation of the lower esophageal and gastric cardiac varices. |
| PubMedID- 21485513 | Conclusion: the results indicated the effectiveness of therapy with flavonoids hesperidin with diasmin at portal hypertension in patients with alcoholic cirrhosis, which allows to include them in the complex treatment of medicamental prophylaxis of variceal bleeding. |
| PubMedID- 25053449 | Liver collagen in cirrhosis correlates with portal hypertension and liver dysfunction. |
| PubMedID- 20704762 | cirrhosis leads to portal hypertension of varying extents. |
| PubMedID- 21371340 | Ce has made it possible to examine the small bowel mucosa directly and has allowed endoscopists to visualize the mucosal changes in cirrhosis patients with portal hypertension. |
| PubMedID- 23983486 | His medical history was significant for alcoholic cirrhosis with portal hypertension, splenomegaly, hypersplenism, and ascites. |
| PubMedID- 25834800 | If liver fibrosis progress to cirrhosis, complications arising from portal hypertension and functional hepatocyte loss develop. |
| PubMedID- 20300546 | To prevent immediate and late sequelae of hepatolithiasis, such as suppurative cholangitis, septicemia, secondary biliary cirrhosis with resultant portal hypertension, bleeding varices, and hepatic failure 5, aggressive treatment is needed. |
| PubMedID- 25135728 | cirrhosis with portal hypertension is a common disease which has a significant impact on the quality of patients' life. |
| PubMedID- 22558526 | He had cirrhosis and thrombocytopenia with portal hypertension, possibly secondary to alcohol use. |
| PubMedID- 21785606 | Intestinal bacterial overgrowth, seen in patients with advanced cirrhosis as a result of portal hypertension, has been noted to be a prerequisite for the facilitation of bacterial translocation. |
| PubMedID- 24400086 | The hemodynamic alteration of portal hypertension in patients with liver cirrhosis contributes to most of the clinical manifestations of the disease: gastrointestinal bleeding, hepatic encephalopathy, ascites and renal failure. |
| PubMedID- 22034603 | 1 pah is also an uncommon but documented complication of hiv infection, chronic hemolytic anemia, and cirrhosis with portal hypertension. |
| PubMedID- 23275766 | Upper gastrointestinal hemorrhage is a common complication of hepatic cirrhosis with systemic portal hypertension, while rarely caused by pancreatic diseases. |
| PubMedID- 26412302 | Additionally, neo-angiogenesis has been identified as a key mechanism in the progression of liver cirrhosis with portal hypertension3. |
| PubMedID- 25454305 | Portal vein thrombosis (pvt) is a rare event in the general medical setting that commonly complicates cirrhosis with portal hypertension, and can also occur with liver tumors. |
| PubMedID- 21501480 | The obstruction of bile flow results in worsening cholestasis, liver fibrosis, and cirrhosis, which lead to portal hypertension and a decline in hepatic synthetic function. |
| PubMedID- 21116340 | Patients with cirrhosis and signs of portal hypertension (platelet count <140,000/mm3) should have screening endoscopy. |
| PubMedID- 25013336 | Laparoscopic cholecystectomy has been reported in portal hypertension patients with cirrhosis of the liver. |
| PubMedID- 25658710 | However, advanced liver disease, defined as multilobular cirrhosis frequently with portal hypertension, occurs in only 5–10% of individuals with cf . |
| PubMedID- 25649410 | The peripheral arterial vasodilation theory is the most widely accepted explanation for the pathophysiology of hrs (figure 1) 1, which proposes that splanchnic vasodilation that occurs as a consequence of portal hypertension with cirrhosis is the inciting factor for the development of hrs. |
| PubMedID- 24439187 | The causes of ev included portal hypertension with cirrhosis in 52 cases (42 of hepatitis as dominant, 5 of alcoholic, 3 of biliary). |
| PubMedID- 24099470 | Background: the hepatic venous pressure gradient (hvpg) is an invasive, but important diagnostic and prognostic marker in cirrhosis with portal hypertension (pht). |
| PubMedID- 26192141 | The management of portal hypertension in cirrhosis has evolved over time, leading to improvements in the care and survival of patients with varices and variceal hemorrhage, particularly in patients who achieve a significant reduction in portal pressure. |
| PubMedID- 26370856 | Hypothyroidism enhanced portal hypertension in a patient with alcoholic liver cirrhosis, resulting in the development of ascites. |
| PubMedID- 24574834 | Variceal bleeding is one of the most fatal complications of portal hypertension in patients with liver cirrhosis . |
| PubMedID- 24851522 | Aim: cirrhosis with portal hypertension (pht) may be associated with increased small intestinal permeability (sip), predisposing to malnutrition and bacterial translocation causing septicaemia, endotoxaemia and spontaneous bacterial peritonitis. |