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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease pancreatitis
Symptom |pain
Sentences 88
PubMedID- 20585364 The cause of pain in patients with chronic pancreatitis (cp) is multifactorial, one of which is regarded to be pancreatic ductal hypertension.
PubMedID- 20717860 Aim: large pancreatic ductal calculi and pain are a feature of chronic calcific pancreatitis (ccp) in the tropics.
PubMedID- 26471102 The indications for eus procedures were abdominal pain with chronic pancreatitis (3) and management of symptomatic pancreaticobiliary cysts/pseudocysts observed on previous imaging (3).
PubMedID- 24868557 Nowadays, ts for pain relief of chronic pancreatitis is widely performed, and some reports have studied its main beneficial effects for pain reduction .
PubMedID- 21397320 pain in the form of recurrent attacks of pancreatitis (representing paralysis of apical exocytosis in acinar cells) or constant and disabling pain is usually the main symptom.
PubMedID- 23188944 Serum amylase and lipase levels are widely used as screening tests for acute pancreatitis in patients with acute abdominal pain or back pain.
PubMedID- 22879908 All patients (24 women, 40 men; median age 53 years (iqr (interquartile range) 45–62)) had pain due to chronic pancreatitis and were on a stable analgesic therapy.
PubMedID- 20208316 Micronutrient therapy, designed to buttress tissue methyl and thiol groups, curbs attacks and controls background pain in patients with chronic pancreatitis, irrespective of aetiology.
PubMedID- 22936895 In terms of specific pharmacotherapies, two double-blind, randomized, placebo-controlled studies by safdi et al32 and whitcomb et al33 revealed that pancrelipase (creon) substantially improved clinical symptoms, including stool consistency and abdominal pain, in patients with chronic pancreatitis (table 2).
PubMedID- 24402765 Background: the underlying pain mechanisms of chronic pancreatitis (cp) are incompletely understood, but recent research points to involvement of pathological central nervous system processing involving pain-relevant brain areas.
PubMedID- 22195253 Some randomized trials,6,7 but not all,8-10 have shown that abdominal pain in patients with chronic pancreatitis improves with pancreatic enzyme supplementation therapy.
PubMedID- 22619712 The kappa receptor agonist adl 10-0101 reduced pain in patients with pancreatitis without influencing heart rate, respiratory rate, oxygen saturation, or causing nausea.
PubMedID- 20583516 By contrast, chronic pancreatitis presented with increased pain (98 and 49%, respectively, p < 0.001) and nausea (68 and 32%, respectively, p < 0.001).
PubMedID- 24795752 It is associated with recurrent, severe abdominal pain, increased risk of acute pancreatitis and other morbidities such as pulmonary embolism-like syndrome, coronary heart disease with or without atherosclerosis, and metabolic consequences of pancreatic insufficiency, including insulinopenic diabetes (brunzell and deeb, 2001; tremblay et al., 2011).
PubMedID- 22225742 Patients and methods: we report the case of a young female patient without any noteworthy prior history, who was hospitalised for abdominal pain associated with acute pancreatitis possibly related to sle with associated haemophagocytic syndrome.
PubMedID- 24912390 Conventional treatment strategies and recent changes in the treatment of pain in patients with chronic pancreatitis are outlined.
PubMedID- 24297649 Methods: total pancreatectomy and subsequent islet autotransplantation were performed in a 16-year-old boy with intractable pain due to chronic pancreatitis in the setting of ulcerative colitis and primary sclerosing cholangitis (psc).
PubMedID- 24949394 The patient who underwent eus-fna had severe epigastric pain due to acute pancreatitis requiring hospitalization for 3 days with improvement.
PubMedID- 26134773 Background and study aims: endoscopic ultrasound - guided celiac plexus block (eus-cpb) is an established treatment for pain in patients with chronic pancreatitis (cp), but the effectiveness and safety of repeated procedures are unknown.
PubMedID- 23321890 The patient was a 53-year-old man with a 20-year history of debilitating upper abdominal pain associated with chronic pancreatitis secondary to pancreatic divisum.
PubMedID- 24194972 Acute pancreatitis frequently presents with abdomen pain but may presents with various skin manifestations as rash and rarely, pancreatic panniculitis.
PubMedID- 23548879 Objective: we aimed to determine if intravenous synthetic human secretin (shs) improves refractory type b pain in patients with chronic pancreatitis (cp).
PubMedID- 25083089 Methods: pain in patients with chronic pancreatitis (n = 314), pancreatic cancer (n = 469), and other pancreatic tumors (n = 249) including mucinous (n = 20) and serous cystadenoma (n = 31), invasive (n = 37) and non-invasive intraductal papillary mucinous neoplasia (ipmn; n = 48), low stage (n = 18) and high stage neuroendocrine neoplasia (n = 44), and ampullary cancer (n = 51) was registered and correlated with clinicopathological data.
PubMedID- 22782018 The central acting gabapentoid pregabalin affords a modest 12% pain reduction in patients with chronic pancreatitis but approximately 30% of patients have significant side effects.
PubMedID- 24363949 Chronic pancreatitis simulating cirrhosis with acute abdominal pain, high gastrointestinal bleeding, and ascites is an unexpected association.
PubMedID- 21963786 Background & aims: the chronic, persistent pain associated with chronic pancreatitis (cp) has many characteristics of neuropathic pain, initiated and maintained by the activation of spinal microglia.
PubMedID- 20531238 Here, we explored the potential role of bk receptors in pain associated with persistent pancreatitis in rats.
PubMedID- 20710131 Background: chronic pancreatitis is commonly associated with debilitating abdominal pain, in part due to pancreatic duct obstruction.
PubMedID- 22558556 Several years later, in a controlled double-blind study, a danish group achieved a clear reduction in the frequency and intensity of pain in patients with acute pancreatitis by administering indomethacin suppositories 50 mg twice daily for 7 days.
PubMedID- 22299073 Objectives: the identification of hyperamylasaemia insufficient to confidently diagnose acute pancreatitis in patients with epigastric pain poses a clinical dilemma.
PubMedID- 21386641 Case report: this article describes a four-year-old girl who presented with severe abdominal pain and features suggestive of acute pancreatitis, who developed gradual distension of the abdomen, and was found to have a ruptured bile duct, producing biliary peritonitis.
PubMedID- 20599324 Tb-2-081 effectively reduces pancreatitis-induced pain through peripheral mechanisms that are likely due to (a) increased expression of il-6 in the drg and (b) il-6-mediated sensitization of nociceptive neurons.
PubMedID- 24960492 Other indications include sympathetic disorders such as splanchnic pain associated with pancreatitis (t4–t6), causalgia, reflex sympathetic dystrophy, and post-traumatic pain syndrome.4,5,11,12 after tds, 80% to 90% of patients with peripheral vascular disease have early relief of symptoms, and most of them (78%) remain significantly better even many years after surgery.4,5,13–15 surprisingly, even larger series reporting tds have not included patients with buerger disease, perhaps because of its low prevalence in western countries.1 increased magnification with the thoracoscopic approach permits better visualization and identification of collateral branches and preganglionic fibers, thus ensuring complete excision with good results.
PubMedID- 24646025 Including this hospitalization, she had two previous episodes of abdominal pain and was diagnosed with acute pancreatitis after intake of fatty food.
PubMedID- 24944153 Conclusions: data from this study supports considering early surgery for pain management in patients with chronic pancreatitis, with the potential of a reduced risk of pancreatic insufficiency and the need for further intervention.
PubMedID- 23995575 A surgical procedure is the only way to relieve intractable pain in patients with chronic pancreatitis and an inflammatory mass in the pancreas head.
PubMedID- 25406464 Necrosis or pseudocyst)orc) need for intervention (drainage or surgery)revised atlanta classificationatwo out of three:a) pain consistent with acute pancreatitisb) amylase or lipase >3 times normal limitc) characteristic findings on abdominal imagingandd) no organ dysfunction or complicationsa) transient organ failure <48 hoursorb) local or systemic complications without persistent organ failurea) persistent single or multi-organ failure >48 hoursorb) present or persistent systemic inflammatory response syndrome (sirs)athese criteria were developed for acute pancreatitis, not specifically for post-ercp pancreatitis.
PubMedID- 23923353 Our study aimed to analyze factors associated with previous abdominal pain episodes in patients with biliary pancreatitis, and elucidate its possible pancreatic origin.

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