eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | neuropathy, peripheral |
| Symptom | |pain |
| Sentences | 77 |
| PubMedID- 24294303 | These include neuropathic pain associated with diabetic peripheral neuropathy, fibromyalgia, chronic low back pain, and osteoarthritis knee pain (oakp). |
| PubMedID- 21569381 | Neuropathic pain associated with peripheral neuropathy can manifest as severe and intractable pain. |
| PubMedID- 21571233 | Participants: subjects were 114 hiv-infected men with pain associated with peripheral neuropathy in the early 1990s, when antiretroviral drug cocktails were just beginning to be available in experimental form. |
| PubMedID- 26444970 | Gabapentin has been reported to be effective for pain associated with various peripheral neuropathies in clinical trials , but requires several weeks of treatment before an attenuating effect is observed. |
| PubMedID- 22003419 | Inhalants can also cause peripheral neuropathy leading to chronic pain and vision-impairing optic nerve damage (e.g., twardowschy et al., 2008). |
| PubMedID- 23771401 | A number of agents from diverse pharmacological classes are used to treat neuropathic pain associated with diabetic peripheral neuropathy. |
| PubMedID- 21713059 | Pregabalin (lyrica) is a second-generation compound structurally related to gabapentin and approved in the us for the management of neuropathic pain associated with diabetic peripheral neuropathy, postherpetic neuralgia, fibromyalgia, and as adjunctive therapy for adults with partial onset seizures and for generalized anxiety disorder (gad). |
| PubMedID- 22415454 | Further data supporting that paclitaxel-associated acute pain syndrome is associated with development of peripheral neuropathy: north central cancer treatment group trial n08c1. |
| PubMedID- 24348072 | Duloxetine (cymbalta®; eli lilly and company, indianapolis, in, usa) is an snri that is approved by the us food and drug administration (fda) for the treatment of major depressive disorder and generalized anxiety disorder and the management of neuropathic pain associated with diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain associated with osteoarthritis and chronic low back pain. |
| PubMedID- 20556211 | Duloxetine has been proven superior to placebo in three 12-week randomized, placebo-controlled trials that enrolled patients with pain due to diabetic peripheral neuropathy . |
| PubMedID- 23937282 | Objectives: to compare adverse effects, tolerability and efficacy of the tricyclic antidepressants (tcas) amitriptyline and nortriptyline in management of neuropathic pain due to peripheral neuropathy (pn). |
| PubMedID- 20113408 | Substitution of gabapentin therapy with pregabalin therapy in neuropathic pain due to peripheral neuropathy. |
| PubMedID- 21606948 | A recent paper describing the results of a randomized clinical trial of the potent α4β2 neuronal nicotinic agonist, abt-594, in the context of the management of pain associated with diabetic peripheral neuropathy44, found that treatment emergent adverse events (including nausea, dizziness, and vomiting) were very high and three to four times more common than that seen in the placebo condition. |
| PubMedID- 26439233 | Objective: current therapies for diabetic peripheral neuropathy with pain mask the painful symptoms while the underlying pathology continues to progress. |
| PubMedID- 25556685 | peripheral neuropathy can lead to neuropathic pain in a subset of patients. |
| PubMedID- 26049779 | Background: duloxetine is an antidepressant effective for major depressive disorder and also the alleviation of pain for patients with diabetic peripheral neuropathy, chronic musculoskeletal pain, and fibromyalgia. |
| PubMedID- 24855395 | We have also safely treated patients on stable medication regimens for pain associated with peripheral neuropathy (eg, pregabalin, gabapentin) with carfilzomib. |
| PubMedID- 26322641 | Radiprodil is an nr2b-selective nmda receptor antagonist which reached phase 2 for the treatment of neuropathic pain associated with diabetic peripheral neuropathy, but was stopped due to a lack of significant reduction in daily pain scores . |
| PubMedID- 21935494 | A retrospective study for scs for pain control of 30 peripheral neuropathies revealed that causalgic and diabetic neuropathic pain seem to respond relatively well, whereas postherpetic pain and intercostal neuralgia syndromes seem to respond less favorably to the long-term beneficial effects of scs . |
| PubMedID- 24260511 | Paclitaxel is known to induce sensory peripheral neuropathy with burning pain symptoms, allodynia, hyperalgesia tingling and numbness . |
| PubMedID- 22608666 | Evidence supports the use of specific anticonvulsants and antidepressants for pain management in patients with diabetic peripheral neuropathy. |
| PubMedID- 23887339 | Objectives: this study used a randomized withdrawal design to evaluate the efficacy of pregabalin versus placebo for pain relief in patients with painful diabetic peripheral neuropathy inadequately treated by other therapies. |
| PubMedID- 25594611 | Subjects: patients with pain due to diabetic peripheral neuropathy (dpn) or postherpetic neuralgia (phn). |
| PubMedID- 25968451 | Objectives: to evaluate pregabalin's efficacy and safety versus placebo to reduce pain in subjects with diabetic peripheral neuropathy (dpn) using a concomitant nonsteroidal anti-inflammatory drug (nsaid). |
| PubMedID- 19674790 | peripheral neuropathy (pn), with neuropathic pain as main symptom, represents the dose-limiting toxicity of the proteasome inhibitor bortezomib. |
| PubMedID- 24330406 | Objective: to evaluate the predictive value of disturbed sleep on the ability of pregabalin to reduce pain associated with diabetic peripheral neuropathy (dpn) and post-herpetic neuralgia (phn). |
| PubMedID- 25018648 | Clinical experience with desvenlafaxine in treatment of pain associated with diabetic peripheral neuropathy. |
Page: 1 2