eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | metabolic syndrome x |
| Symptom | |diabetes |
| Sentences | 161 |
| PubMedID- 23853755 | The metabolic state of hyperglycemia is closely related to the pathophysiological state of metabolic syndrome associated with diabetes (després and lemieux 2006). |
| PubMedID- 24054926 | Inconsistencies or gaps were particularly obvious for studies of sex or gender differences in age and optimal measures of body size for chd outcomes, and in the striking interface of diabetes and people with the metabolic syndrome, most of whom have unrecognized diabetes. |
| PubMedID- 22295727 | Other factors associated with less favorable ldl goal attainment were coronary heart disease, carotid artery disease, diabetes, 10-year risk of > 20%, and metabolic syndrome (p < 0.05 for all). |
| PubMedID- 20586225 | The consequence is a metabolic syndrome with type 2 diabetes and increased cardiovascular mortality. |
| PubMedID- 20813084 | Overweight, obesity and metabolic syndrome in children with type 1 diabetes melllitus. |
| PubMedID- 20864516 | Among the earth study participants with diabetes, the prevalence of the metabolic syndrome was 86.6 (83.7–88.8) with little difference between men and women. |
| PubMedID- 23776850 | Prevalence of metabolic syndrome with increasing mdrf-indian diabetes risk score (idrs) in subjects with normal glucose tolerance (*p value <0.001 compared with low risk. |
| PubMedID- 22113483 | Sensitivity analyses were undertaken using the revised ncep atp iii definition (glucose cut point >5.6mmol/l) and the international diabetes federation (idf) definitions of metabolic syndrome (zimmet et al., 2005). |
| PubMedID- 20012885 | This study determines the prediction of low-risk lifestyle on type 2 diabetes in those with and without metabolic syndrome in a pooled sample of two representative finnish cohorts, collected in 1978-1980 and 2000-2001. |
| PubMedID- 21691165 | Objective: to assess a cluster of risk factors, including parameters of the metabolic syndrome, in women with gestational diabetes mellitus (gdm) early after delivery, that features the best prediction for developing diabetes. |
| PubMedID- 21055836 | Methods: 150 men were recruited from a genetic screening programme for hereditary hemocromatosis (hh) and were tested for type 2 diabetes, other components of the metabolic syndrome, beta cell function (bcf), insulin sensitivity, high-sensitivity c-reactive protein and iron overload. |
| PubMedID- 21994081 | Long-term effect of metabolic syndrome with and without diabetes mellitus on coronary revascularization in japanese patients undergoing percutaneous coronary intervention. |
| PubMedID- 22540858 | For the type 2 diabetes (t2d), signs of the metabolic syndrome with high risk for chronic micro- and macro-vascular complications are typical. |
| PubMedID- 24072533 | In vitro studies using human aortic endothelial cells showed that ebselen abrogates h2o2‐induced increases in p‐ikk, p‐jnk, tumor necrosis factor–α, and nox2.24,46 in zucker diabetic fat rats, a model of type 2 diabetes associated with metabolic syndrome, ebselen prevented premature endothelial cell senescence and improved endothelial dysfunction (improved acetylcholine response).23 cellular antioxidant enzymes such as glutathione peroxidase 1 and superoxide dismutase have a central role in the control of reactive oxygen species. |
| PubMedID- 26457580 | Abbreviations: art, antiretroviral therapy; bmi, body mass index; bp, blood pressure; frs, framingham risk score; hiv, human immunodeficiency virus; mets-idf, international diabetes foundation definition of metabolic syndrome; mets-ncep, national cholesterol education program defined metabolic syndrome; pi–haart, protease inhibitor-based highly active antiretroviral therapy; sd, standard deviation; vat; visceral adipose tissue; wc, waist circumference. |
| PubMedID- 22695027 | In general, patients with type 2 diabetes commonly have components of metabolic syndrome (e.g. |
| PubMedID- 23934728 | The most common are cardiovascular diseases (associated with atherosclerosis, hypertension and cardiac hypertrophy), cancer, diabetes (and other complications of metabolic syndrome), alzheimer and parkinson diseases, macular degeneration and so on. |
| PubMedID- 23913501 | The prevalence of metabolic syndrome in persons with type 2 diabetes at the lagos university tteaching hospital, lagos, nigeria. |
| PubMedID- 20424809 | Prevalence of metabolic syndrome with international diabetes federation criteria and atp iii program in patients 65 years of age or older. |
| PubMedID- 24159331 | diabetes mellitus, development of metabolic syndrome, increased risk of death due to cardiovascular diseases, and pathologic bone fractures due to severe loss of bone are well-known negative effects of iatrogenic or spontaneous t depletion . |
| PubMedID- 20666270 | We sought to determine the impact of the metabolic syndrome, defined with international diabetes federation criteria, on arterial pulse wave velocity. |
| PubMedID- 26558285 | These findings suggest that enhanced glycolysis and the tca cycle might contribute to the development of diabetes associated with metabolic syndrome. |
| PubMedID- 21205020 | Objectives: to examine whether interleukin-1 receptor antagonist (il-1ra) is a predictor for clinically incident diabetes in subjects with metabolic syndrome (mets) and whether its predictive power is independent of c-reactive protein (crp), an established marker of inflammation. |
| PubMedID- 20587704 | Research design and methods: the study involved a group of 242 metabolic syndrome patients with or without pre-diabetes and randomized to atorvastatin, fenofibrate, or placebo. |
| PubMedID- 25550516 | These findings are important to consider in designing drugs to target type 2 diabetes and other features of the "metabolic syndrome." medical school, boston, ma 02115; school, boston, ma 02215; and. |
| PubMedID- 22322078 | Pre-diabetes commonly associates with the metabolic syndrome. |
| PubMedID- 22110170 | In future cohort studies attention should be paid to putative pathogenic pathways, such as abnormal insulin production, insulin resistance, therapies for glucose control as well as inflammation and other cardiovascular risk factors that frequently cluster with diabetes within the spectrum of the metabolic syndrome. |
| PubMedID- 22144985 | This in utero programming seems to create a kind of “metabolic memory,” since physiological anomalies of gestational period are responsible for the onset of diseases in offspring at adulthood, such as type 2 diabetes and obesity associated with metabolic syndrome. |
| PubMedID- 21252478 | diabetes mellitus is one of the most prevalent metabolic syndromes worldwide. |
| PubMedID- 22328881 | The studies incorporated in the present analysis are:assessing the treatment effect in metabolic syndrome without perceptible diabetes (attempt) study, which included patients with mets but no dm or cvd ;implementation of strategy for the management of overt dyslipidemia (improve-dyslipidemia) study, which included patients with dyslipidaemia with or without dm, with or without cvd ;standardized arrangement for a guideline-driven treatment of the metabolic syndrome (sage-mets) study, which included patients with mets but no cvd ;implementation of guidelines for the management of arterial hypertension (impulsion) study, which included patients with hypertension with or without dm but no cvd ;initiative for a new diabetes therapeutic approach in a mediterranean country (indeed) study, which included patients with diabetes but no cvd . |
| PubMedID- 20566663 | To conclude, we have found that patients fulfilling the international diabetes federation criteria of metabolic syndrome have increased brain ffa uptake when compared with healthy subjects. |
| PubMedID- 24744548 | on the other hand, the drugs used to manage schizophrenics, though beneficial, have been reported to produce certain side effects such as considerable weight gain, diabetes, and risk of metabolic syndrome. |
| PubMedID- 22471842 | Apolipoproteins a-i and b as components of metabolic syndrome with respect to diabetes status: a factor analysis. |
| PubMedID- 24411997 | However, few studies are available on the impact of sleep duration on metabolic syndrome in patients with diabetes, who were at high risk for cardiovascular diseases (cvd). |
| PubMedID- 23949560 | The insulin resistance milieu of type 2 diabetes is closely associated with metabolic syndrome—a clustering of risk factors that includes hypertension, abdominal adiposity, dyslipidemia, and inflammation. |
| PubMedID- 25782325 | Clinical evaluation of the influence of certain initial status parameters on the development of type 2 diabetes mellitus in patients with metabolic syndrome. |
| PubMedID- 25940982 | Therefore, a cordycepin treatment during diabetes can improve some of the metabolic syndrome symptoms by regulation of glucose absorption in vivo. |
| PubMedID- 25561880 | Aim: the dietary contents have a very important role in the management of metabolic syndrome along with type 2 diabetes mellitus (t2dm). |
| PubMedID- 20966915 | Cd36 variants have been associated with type 2 diabetes, features of the metabolic syndrome, and alterations in lipid metabolism. |
| PubMedID- 21390196 | Fifty nine had isolated metabolic syndrome (group a) and 97 had metabolic syndrome with hypertension and/or diabetes (group b). |
| PubMedID- 20472485 | Those who have the metabolic syndrome with or without diabetes suffer more often from dysexecutive problems and slower psychomotor speed than do other patients. |
| PubMedID- 25954754 | This also means that membrane transporters, including ion channels and transporters, are very important therapeutic targets in several diseases such as cardiovascular disorders, hypertension, dementia, metabolic syndrome associated with diabetes mellitus, and cancer. |
| PubMedID- 24843614 | Furthermore, some studies showed that fish intake reduced the rates of incidence for diabetes in patients with metabolic syndrome, and reduced the rates of death in patients with type 2 diabetes13,14. |
| PubMedID- 21994347 | This review focuses on their role in cardiovascular diseases with emphasis on their implication in the inflammatory processes that accompany heart failure, atherosclerosis, coronary artery disease, and finally obesity and diabetes as components of the ageing-associated metabolic syndrome. |
| PubMedID- 23282254 | diabetes affects approximately 4% of world's population and metabolic syndrome has been directly related to obesity. |
| PubMedID- 20446581 | The cvd mortality of metabolic syndrome with diabetes is higher than those of metabolic syndrome without diabetes (hr, 3.67 vs 1.61). |
| PubMedID- 21140273 | Overweight, obesity and features of metabolic syndrome in children with diabetes treated with insulin pump therapy. |
| PubMedID- 25154537 | Physicians should discuss lipids, weight, and glucose with patients at risk for developing heart disease, diabetes, and other sequelae of the metabolic syndrome. |
| PubMedID- 20823099 | Of significance in the zucker diabetic fat rat, a model of type 2 diabetes associated with the metabolic syndrome, ebselen improved endothelial dysfunction and renal insufficiency (21,22). |
| PubMedID- 21272190 | Aim: we examined the effects of the 11beta-hydroxysteroid dehydrogenase type 1 (hsd1) inhibitor, mk-0916, on the multiple components of the metabolic syndrome (mets) in patients with type 2 diabetes (t2dm) and mets. |