eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | herpes simplex |
| Symptom | |infection |
| Sentences | 147 |
| PubMedID- 21637835 | Background: co-infection with herpes simplex virus type 2 (hsv-2) has been associated with increased hiv-1 rna levels and immune activation, two predictors of hiv-1 progression. |
| PubMedID- 23487467 | A proautophagic antiviral role for the cellular prion protein identified by infection with a herpes simplex virus 1 icp34.5 mutant. |
| PubMedID- 21752961 | Primary infection with herpes simplex virus (hsv) results in lifelong latency within sensory neurones followed by periodic episodes of virus reactivation. |
| PubMedID- 25859317 | Our patient also had a co-infection with ocular herpes simplex virus; therefore, we cannot exclude that his diaphragmatic failure could actually have been caused by herpes infection. |
| PubMedID- 22937690 | Goal: goal of this study is to analyze the incidence of early infection with rubella virus, herpes simplex, cytomegalovirus and epstein-barr, in ms patients using titers of igg and igm antibodies. |
| PubMedID- 22114563 | One example is infection with herpes simplex virus type 1 (hsv-1), for which latency is controlled by ifn-γ produced by cd8 t and by granzyme b-mediated degradation of the hsv-1 immediate early protein icp4 . |
| PubMedID- 25690796 | It was found that, during infection with herpes simplex virus (hsv), the viral gene product icp0 promotes degradation of 4ebp-1 via proteasome, avoiding interaction with eif4e. |
| PubMedID- 25359413 | Intrauterine infection with herpes simplex virus, although very rare, has devastating effects on multiple organ systems in the fetus and can lead to in utero fetal demise. |
| PubMedID- 25139839 | Chronic infection with herpes simplex virus 2 (hsv-2), also known as human herpes virus 2, has been shown to facilitate hiv infection and speed the progression to immunodeficiency disease. |
| PubMedID- 21045370 | Background: infection with herpes simplex virus type-2 (hsv-2) is the primary cause of genital herpes and the most common cause of genital ulcer disease (gud) worldwide. |
| PubMedID- 20140199 | In support of this model, infection studies with herpes simplex virus (hsv) and mouse hepatitis virus (mhv), two well established models of viral encephalitis, have demonstrated the importance of tregs in limiting proinflammatory cytokine and chemokine responses to protect the cns and enhance survival ,. |
| PubMedID- 20418869 | We show a similar function for mir-132 during infection of monocytes with herpes simplex virus-1 (hsv-1) and human cytomegalovirus (hcmv). |
| PubMedID- 22673383 | We describe two cases of recurrent erythema multiforme, both associated to infection with herpes simplex virus. |
| PubMedID- 25386284 | Eczema herpeticum (eh), or kaposi's varicelliform eruption, is a skin infection with herpes simplex type i virus (hsv-1) that occurs in patients with compromised skin integrity, such as atopic dermatitis (ad). |
| PubMedID- 24159767 | Destructive changes in the mice testes in retrograde infection with herpes simplex virus. |
| PubMedID- 24115949 | In the skin, the anatomical localization and migration pattern of cd4+ and cd8+ memory t cells are substantially different following epicutaneous infection with herpes simplex virus as a result of distinct migratory programing in these two subpopulations (111). |
| PubMedID- 21099403 | Conclusions: this case reports a reactivation of latent herpes simplex virus with productive ocular infection, triggered by mmc therapy and highlights the importance of awareness of this possible risk associated with the use of mmc. |
| PubMedID- 22405261 | Finally, lokensgard and colleagues observed an early neutrophil and inflammatory monocyte response in the brain following infection with herpes simplex virus 1 and this response preceded lymphocyte infiltration by a week 6. |
| PubMedID- 25454310 | Neonatal airway infection due to herpes simplex virus. |
| PubMedID- 23940750 | We present here evidence that fm-mscs are fully permissive to infection with herpes simplex virus 1 and 2 (hsv-1 and hsv-2), varicella zoster virus (vzv), and human cytomegalovirus (hcmv), but not with epstein-barr virus (ebv), human herpesvirus-6, 7 and 8 (hhv-6, 7, 8) although these viruses are capable of entering fm-mscs and transient, limited viral gene expression occurs. |
| PubMedID- 24283809 | We present this case of head and neck space infection presenting with herpes simplex virus, as it is rarely seen. |
| PubMedID- 20817252 | Neutrophils are prominent in epidermal and dermal layers of human herpetic lesions and are rapidly recruited into the skin follow epidermal abrasion and infection of mice with herpes simplex virus type-1 (hsv-1). |
| PubMedID- 25837802 | Genital herpes is an important global health problem usually caused by a sexually transmitted infection with herpes simplex virus type 2 (hsv-2), although infection by type 1 (hsv-1) is becoming increasingly common 1. |
| PubMedID- 23863878 | Chromatin dynamics during lytic infection with herpes simplex virus 1. |
| PubMedID- 24407287 | Furthermore, il-1beta production was markedly enhanced in these macrophages in response to both nlrp3 and aim2 inflammasome activation and following bone marrow-derived macrophage infection with herpes simplex virus-1 (hsv-1) and salmonella typhimurium. |
| PubMedID- 21750616 | In all patients, a meticulous diagnostic approach to inflammation was carried out, concerning infectious diseases (including brucellosis, tuberculosis, syphilis, toxoplasmosis, toxocariasis, leptospirosis, lyme disease, bartonellosis and infection due to herpes simplex virus, herpes zoster virus, cytomegalovirus, epstein–barr virus and human immunodeficiency virus i+ii), sarcoidosis and other autoimmune diseases, and specific idiopathic uveitic syndromes as well. |
| PubMedID- 20871659 | infection with herpes simplex is most common in these patients; the reactivation of the varicella-zoster virus (vzv) is less common . |
| PubMedID- 21209804 | Simultaneously, acyclovir was intravenously used to protect against mucocutaneous infection with herpes simplex virus. |
| PubMedID- 21496359 | Introduction: genital herpes is an infection with herpes simplex virus type 1 (hsv-1) or type 2 (hsv-2), and is among the most common sexually transmitted diseases. |
| PubMedID- 25741165 | Biopsies taken from the oesophagus and duodenum demonstrated infection with herpes simplex virus (hsv) and cytomegalovirus (cmv) respectively. |
| PubMedID- 23087395 | Epidemiology, clinical presentation, and antibody response to primary infection with herpes simplex virus type 1 and type 2 in young women. |
| PubMedID- 22567467 | The working diagnosis at this time was disseminated infection with herpes simplex virus (hsv). |
| PubMedID- 22174686 | Ocular infection with herpes simplex virus (hsv) can result in a chronic immuno-inflammatory reaction in the cornea which represents a common cause of human blindness . |
| PubMedID- 21354709 | The hypothesis of an indirect antiviral effect on the immune system of propranolol has been confirmed on a small scale by treating viral infections with herpes simplex i, shingles and influenza virus infections diagnosed clinically; in one case influenza virus infection was confirmed with a specific influenza test. |
| PubMedID- 23028205 | Potential complications resulting from systemic steroid therapy include increased intraocular pressure and cataract formation, osteoporosis, hyperglycemia, aseptic bone necrosis, gastrointestinal ulcers, pancreatitis, myopathy, psychosis, delayed wound healing, cushingoid features, secondary infection and reactivation of latent herpes simplex or tuberculosis. |
| PubMedID- 24807710 | The development of immunization strategies to protect against ocular infection with herpes simplex virus 1 (hsv-1) must address the issue of the effects of the strategy on the establishment of latency in the trigeminal ganglia (tg). |
| PubMedID- 25002588 | The interferon gamma-inducible protein 16 (ifi16) has recently been linked to the detection of nuclear and cytosolic dna during infection with herpes simplex virus-1 and hiv. |
| PubMedID- 23442925 | Despite recent advances in vaccine design and strategies, latent infection with herpes simplex virus (hsv) remains a formidable challenge. |
| PubMedID- 25853497 | Introduction: genital herpes is an infection with herpes simplex virus type 1 (hsv-1) or type 2 (hsv-2), and is among the most common sexually transmitted diseases. |
| PubMedID- 24795560 | Moreover, in vivo and cell culture experiments reveal that infection with herpes simplex virus type 1 (hsv1: a virus suggested to be implicated in ad development) causes activation of the pkr-eif2α pathway, resulting in elevations of bace1 expression and aβ/c99 generation (ill-raga et al., 2011). |
| PubMedID- 22984519 | One mixed infection with herpes simplex virus in a 22 month old toddler. |
| PubMedID- 21423768 | In addition, upon viral infection, icp0 of herpes simplex virus induces cell cycle arrest in g1 by both p53-mediated and p53-independent pathways . |
| PubMedID- 22367376 | In this report, we describe a lymphocytic infiltrate in an ulcerated lesion on the lip of a 53-year-old man resulting from infection with herpes simplex virus type 2. |
| PubMedID- 25992785 | An ~80% reduction in infection was observed with herpes simplex virus (hsv) 1. however, reduction of hsv 2 infection was less remarkable (~40% reduction). |
| PubMedID- 20824216 | In addition, opn has been shown to contribute to th1 responses in vivo, including experimental autoimmune encephalomyelitis, infection with herpes simplex virus-1 and with plasmodium chabaudi chabaudi , , . |
| PubMedID- 24740100 | Prevalent infection with human herpes simplex 2 (hsv-2) or human papillomavirus (hpv) is associated with increased human immunodeficiency virus (hiv) acquisition. |
| PubMedID- 20829726 | Histologic and immunohistochemical analysis of the excised mass revealed infection with herpes simplex virus types 1 and 2 with exuberant inflammatory reaction and granulation tissue consistent with the diagnosis of herpes simplex vegetans. |
| PubMedID- 21283640 | infection of cells with herpes simplex virus (hsv) requires binding of specific cell surface receptors to viral ligands, with subsequent fusion of the viral envelope with a cell membrane and delivery of viral dna into the cell . |
| PubMedID- 24371054 | infection with herpes simplex virus type 1 (hsv-1) results in the rapid elimination of mitochondrial dna (mtdna) from host cells. |
| PubMedID- 22808056 | Cutaneous infection with herpes simplex virus-1 (hsv-1) is an interesting localized infection model to study the hsv-1 specific cd8 t cell response . |