eRAM
encyclopedia of Rare Disease Annotation for Precision Medicine
| Disease | cystic fibrosis |
| Symptom | |infections |
| Sentences | 163 |
| PubMedID- 24856524 | infections in patients with cystic fibrosis: diagnostic microbiology update. |
| PubMedID- 24709961 | These strains are genetically diverse, differ from strains that cause chronic lung infections in patients with cystic fibrosis, and exhibit heterogeneous production of virulence factors in vitro. |
| PubMedID- 24637508 | Aeruginosa is an opportunistic bacterial pathogen which establishes chronic pulmonary infections in patients with cystic fibrosis (cf). |
| PubMedID- 19805554 | The results of the study show that the high concentrations of levofloxacin readily achievable in the lung following aerosol delivery may be useful for the management of pulmonary infections in patients with cystic fibrosis. |
| PubMedID- 24260482 | Burkholderia cepacia complex (bcc) is an opportunistic bacterial pathogen that causes chronic infections in people with cystic fibrosis (cf). |
| PubMedID- 24633206 | Chelonae infections, including those with underlying cystic fibrosis, despite failure of prior antibiotic therapy. |
| PubMedID- 21926193 | Although only poorly documented, it can be assumed that intensive antibiotic treatments of chronic lung infections in patients with cystic fibrosis (cf) also affect the diversity and metabolic functioning of the gastrointestinal microbiota and potentially lead to a state of dysbiosis. |
| PubMedID- 24461904 | Respiratory infections in patients with cystic fibrosis undergoing lung transplantation. |
| PubMedID- 22629423 | The bcc, which is a complex composed of more than 10 burkholderia species, including b. cepacia, b. cenocepacia, and b. multivorans, is a group of nosocomial pathogens of increasing concern as these bacteria cause respiratory and systemic infections in patients with cystic fibrosis (cf) or chronic granulomatous disease, and in other immuno-compromised patients . |
| PubMedID- 21114855 | For example, in this study, the target proteins were from p. aeruginosa, a gram negative bacterial opportunistic pathogen that causes serious lung infections in people with cystic fibrosis, and several tm proteins involved in infection were found to be expressed at sufficient levels for further study. |
| PubMedID- 24672734 | Pseudomonas aeruginosa is an aerobic gram-negative gammaproteobacterium that causes opportunistic infections, particularly in patients with cystic fibrosis where it results in inflammation and sepsis (reviewed by veesenmeyer et al. |
| PubMedID- 26505731 | We identify markers of coordinated initial signaling in macrophages challenged with ligands to prrs of the toll-like receptor (tlr) family and compare this response to that induced by intact bacteria of the burkholderia cenocepacia complex (bcc), an opportunistic pathogen that causes life-threatening infections in patients with cystic fibrosis and chronic granulomatous disease. |
| PubMedID- 23382856 | Background: the genus burkholderia includes pathogenic gram-negative bacteria that cause melioidosis, glanders, and pulmonary infections of patients with cancer and cystic fibrosis. |
| PubMedID- 20941353 | Such within-species polymicrobial infection have been reported mainly in chronic and/or open infections (pseudomonas aeruginosa infections of lung in cystic fibrosis patients and of burn wounds , staphylococcus epidermidis joint prosthesis infection , lung tuberculosis , . |
| PubMedID- 24614163 | Carbapenem resistance poses a major therapeutic challenge for the treatment of p. aeruginosa infections, particularly in patients with cystic fibrosis. |
| PubMedID- 22679547 | Patients who have end stage lung diseases such as cystic fibrosis, bronchiectasia along with secondary lung infections need lung transplantation to prolong their life. |
| PubMedID- 25453270 | Pneumonia, tuberculosis and infections occurring due to cystic fibrosis are in focus of this review. |
| PubMedID- 22555873 | Pseudomonas aeruginosa is an opportunistic pathogen that causes chronic infections in the lungs of individuals with cystic fibrosis. |
| PubMedID- 24575808 | This method has been effectively used for treatment of tuberculosis, leprosy, malaria, hiv, infections associated with cystic fibrosis, and infective endocarditis . |
| PubMedID- 21939536 | Chimaera organisms contributed equally to respiratory tract infections in patients with cystic fibrosis when compared with m. |
| PubMedID- 22798960 | The β-hairpin mimetic pol7080 is currently in a phase i clinical trial in europe, and could represent an important drive in the treatment of chronic lung infections in patients with cystic fibrosis where p. aeruginosa plays a crucial role. |
| PubMedID- 24201191 | Mycobacterium abscessus is a rapidly growing mycobacterium and an emerging human pathogen causing pulmonary infections, especially in patients with cystic fibrosis and other underlying lung disorders (1). |
| PubMedID- 23943728 | Background: the paranasal sinuses can be a bacterial reservoir for pulmonary infections in patients with cystic fibrosis (cf) methodology: in this prospective, non-randomised, uncontrolled, intervention cohort study, the clinical effect of sinus surgery followed by two weeks` intravenous antibiotics, 6 months` antibiotic nasal irrigations was assessed in 106 cf patients. |
| PubMedID- 21797692 | Evidence is accumulating that certain infections, for example, of medical devices, the cystic fibrosis lung, the oral cavity, the gi tract and wounds, are in fact polymicrobial, with more than one microbe involved. |
| PubMedID- 25417708 | Aeruginosa infections among patients with cystic fibrosis. |
| PubMedID- 24688762 | Spectrum of viral infections in patients with cystic fibrosis. |
| PubMedID- 24034668 | It is responsible for serious chronic and often fatal lung infections in patients with cystic fibrosis and acute infections in patients that are immune compromised or have serious burns 1. |
| PubMedID- 21995705 | Bcc bacteria emerged in the 1980s as opportunistic human pathogens responsible for devastating lung infections in people with cystic fibrosis and chronic granulomatous disease 3. |
| PubMedID- 21067332 | Furthermore, we examine the epidemiologic studies of candida albicans, exophiala dermatitidis and scedosporium apiospermum infections in patients with cystic fibrosis. |
| PubMedID- 26187366 | Burkholderia cenocepacia and other members of the burkholderia cepacia complex (bcc) are highly multidrug-resistant bacteria that cause severe pulmonary infections in patients with cystic fibrosis. |
| PubMedID- 23829476 | Burn victims and cystic fibrosis patients ), with infections being initiated through interaction of t4p with cellular receptors . |
| PubMedID- 26438797 | Pseudomonas aeruginosa infections persist in patients with cystic fibrosis (cf) and drive lung disease progression. |
| PubMedID- 24010944 | S. aureus scvs are characterized by their slow growth rate and small colony size relative to the parent strain, and can cause persistent infections in the lungs of cystic fibrosis patients and infections of skin, bone and implanted devices 2. |
| PubMedID- 21977035 | P. aeruginosa causes chronic respiratory infections in people with cystic fibrosis (cf) and acts as opportunistic pathogen causing bacteraemia, urinary tract infections, and hospital acquired pneumonia in patients with burns, urinary catheters, and those on invasive ventilation 1. |
| PubMedID- 24370741 | A new study uses whole-genome and population sequencing approaches to identify evidence of adaptive evolution in burkholderia dolosa genomes isolated from chronic infections in patients with cystic fibrosis. |
| PubMedID- 20948804 | It is also the leading bacterial cause of acute ventilator-associated pneumonia and chronic lung infections in patients with cystic fibrosis (cf). |
| PubMedID- 26070573 | Aerosolized antibiotics have been tested as treatment for bacterial infections in patients with cystic fibrosis (cf), non-cf bronchiectasis (ncfb), and ventilator-associated pneumonia (vap). |
| PubMedID- 25590983 | Rationale: pseudomonas aeruginosa, the predominant cause of chronic airway infections of patients with cystic fibrosis, exhibits extensive phenotypic diversity among isolates within and between sputum samples, but little is known about the underlying genetic diversity. |
| PubMedID- 19889907 | Burkholderia cenocepacia can cause serious infections and epidemics in patients with cystic fibrosis (cf). |
| PubMedID- 25533880 | Among several inhaled beta-lactams, ceftazidime was used with varying success in the prevention and treatment of ventilator-associated pneumonia (vap) and improved clinical outcomes in chronic pseudomonas aeruginosa lower respiratory tract infections (lrtis) in patients with cystic fibrosis (cf) or bronchiectasis. |
| PubMedID- 22150831 | Burkholderia cepacia complex (bcc) bacteria are opportunistic pathogens that cause multiresistant pulmonary infections in patients with cystic fibrosis (cf). |
| PubMedID- 25850766 | Cepacia complex (bcc) which causes opportunistic infections in people with cystic fibrosis and immunocompromised patients. |
| PubMedID- 21208930 | Functional quorum sensing systems are maintained during chronic burkholderia cepacia complex infections in patients with cystic fibrosis. |
| PubMedID- 23620120 | Mycobacterium abscessus is an opportunistic mycobacterial species able to cause chronic pulmonary infections in patients with cystic fibrosis but also soft tissue infections in immunocompetent individuals. |
| PubMedID- 23910799 | Pseudomonas aeruginosa infections are commonly associated with cystic fibrosis, pneumonias, neutropenia and burns. |
| PubMedID- 24532839 | The identification of novel protein targets could contribute to the development of much needed antimicrobial therapies to treat the chronic infections found in patients with cystic fibrosis. |
| PubMedID- 25590621 | These results highlight a dynamic bacterial-host interaction between an opportunistic pathogen that causes chronic infections in the lungs of individuals with cystic fibrosis, an infection site known to be rich in neutrophil dna and neutrophil extracellular traps . |
| PubMedID- 22022288 | Aztreonam (for inhalation solution) for the treatment of chronic lung infections in patients with cystic fibrosis: an evidence-based review. |
| PubMedID- 25865196 | The opportunistic pathogen pseudomonas aeruginosa causes chronic airway infections in patients with cystic fibrosis (cf), and it is directly associated with the morbidity and mortality connected with this disease. |
| PubMedID- 20729192 | The type vi secretion system (t6ss) contributes to the virulence of burkholderia cenocepacia, an opportunistic pathogen causing serious chronic infections in patients with cystic fibrosis. |