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eRAM

encyclopedia of Rare Disease Annotation for Precision Medicine




Disease barrett esophagus
Symptom |adenocarcinoma
Sentences 56
PubMedID- 22272378 found a correlation between cox2 expression and tp53 wild-type status in esophageal adenocarcinoma with barrett's esophagus as a precursor lesion, but not in scc, providing evidence that the participation of p53 in the regulation of cox2 expression in cancer may be dependent on tumor histology.
PubMedID- 21375764 In contrast with the esophageal adenocarcinoma arising from barrett's esophagus in western countries, the major phenotype in the asia-pacific region is esophageal squamous cell carcinoma (escc) .
PubMedID- 22353776 Observational data have also indicated that statins may have protective effects against the development of cancer, for example, modifying the risk of oesophageal adenocarcinoma in patients with existing barrett's oesophagus .
PubMedID- 24765592 In this present study by qumseya et al.,13 among 136 patients with adenocarcinoma or dysplasia of barrett's esophagus, 27% had esophageal stricture.
PubMedID- 25502158 The goal of this study was to determine whether the use of metformin modifies the risk of development of esophageal adenocarcinoma in patients with barrett esophagus.
PubMedID- 22443641 Previously, the risk of progression to esophageal adenocarcinoma in patients with barrett's esophagus was thought to be approximately 1%.

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