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	waterhouse-friderichsen syndrome

Disease ID	1448
Disease	waterhouse-friderichsen syndrome
Definition	A condition of HEMORRHAGE and NECROSIS of the ADRENAL GLAND. It is characterized by rapidly developing ADRENAL INSUFFICIENCY; HYPOTENSION; and widespread cutaneous PURPURA.
Synonym	adrenal hemorrhage syndrome friderichsen-waterhouse syndrome purpura fulminans (waterhouse-friderichsen syndrome) syndrome waterhouse friderichsen waterhouse friderichsen syndrome waterhouse friederichsen syndrome waterhouse-friderichen waterhouse-friderichsen syndrome [disease/finding] waterhouse-friederichsen syndrome
Orphanet	ORPHANET:100067
DOID	DOID:9931
ICD10	ICD10CM:A39.1
UMLS	C0043068
MeSH	D014884
Comorbidity	UMLS \| Disease \| Sentences' Count(Total Sentences:3) C0032285 \| pneumonia \| 1 C0025306 \| meningococcaemia \| 1 C0025306 \| meningococcemia \| 1
Curated Gene	(Waiting for update.)
Inferring Gene	(Waiting for update.)
Text Mined Gene	Entrez_id \| Symbol \| Score \| Resource(Total Genes:14) 23365 \| ARHGEF12 \| 3.054 \| DISEASES 6387 \| CXCL12 \| 1.488 \| DISEASES 11245 \| GPR176 \| 3.602 \| DISEASES 100124700 \| HOTAIR \| 2.783 \| DISEASES 51520 \| LARS \| 2.416 \| DISEASES 23532 \| PRAME \| 2.905 \| DISEASES 51334 \| PRR16 \| 3.593 \| DISEASES 5698 \| PSMB9 \| 4.221 \| DISEASES 5817 \| PVR \| 1.892 \| DISEASES 222546 \| RFX6 \| 3.436 \| DISEASES 26168 \| SENP3 \| 4.254 \| DISEASES 26054 \| SENP6 \| 4.187 \| DISEASES 462 \| SERPINC1 \| 1.018 \| DISEASES 23038 \| WDTC1 \| 1.158 \| DISEASES
Locus	(Waiting for update.)

Disease ID	1448
Disease	waterhouse-friderichsen syndrome
Integrated Phenotype	(Waiting for update.)
Text Mined Phenotype	HPO \| Name \| Sentences' Count(Total Phenotypes:1) HP:0002090 \| Pneumonia \| 1

Disease ID	1448
Disease	waterhouse-friderichsen syndrome
Manually Symptom	UMLS \| Name(Total Manually Symptoms:3) C0087031 \| still's disease C0017086 \| gangrene C0000727 \| acute abdomen
Text Mined Symptom	(Waiting for update.)

Manually Genotype(Total Text Mining Genotypes:0)
(Waiting for update.)

Text Mining Genotype(Total Genotypes:0)
(Waiting for update.)

All Snps(Total Genotypes:0)
(Waiting for update.)

GWASdb Annotation(Total Genotypes:0)
(Waiting for update.)

GWASdb Snp Trait(Total Genotypes:102)
CHR	POS	SNPID	REF	ALT	ORI_SNPID	PMID	P_VALUE	P_VALUE_TEXT	OR/BETA	CI95_TEXT	GWAS_INITIAL_SAMPLE_SIZE	SUB_POPULATION	SUPER_POPULATION	GWAS_TRAIT	HPO_ID	HPO_TERM	DO_ID	DO_TERM	MESH_ID	MESH_TERM	EFO_ID	EFO_TERM	DOLITE_TERM	RISK_ALLELE	PUBLICATION_TYPE	AA	GENE_SYMBOL	TYPE	REFGENE
1	94511717	rs3789399	G	C	rs3789399	20694013	8.67E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
1	94512893	rs544830	C	T	rs544830	20694013	3.60E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
1	94516985	rs1191231	A	C	rs1191231	20694013	6.89E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
1	94523113	rs497511	G	A	rs497511	20694013	1.76E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
1	94524784	rs550060	A	G	rs550060	20694013	1.84E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
1	165622207	rs2297765	C	T	rs2297765	20694013	6.84E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
1	178661341	rs16853243	C	T	rs16853243	20694013	4.32E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
1	178686331	rs16853302	A	C	rs16853302	20694013	4.39E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
1	194035948	rs634899	T	C	rs634899	20694013	1.80E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
1	196709774	rs1065489	G	T	rs1065489	20694013	4.74E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
1	196710157	rs11582939	C	T	rs11582939	20694013	6.13E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
1	196760417	rs426736	A	G	rs426736	20694013	5.00E-13	NA	1.59	[1.41-1.82]	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
1	209779953	rs880782	G	A	rs880782	20694013	9.11E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
2	125217386	rs2420864	T	C	rs2420864	20694013	2.77E-08	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
2	174999188	rs4972431	C	T	rs4972431	20694013	1.38E-07	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
2	207453310	rs3821170	C	T	rs3821170	20694013	7.01E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
2	215790001	rs10204986	T	G	rs10204986	20694013	8.07E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
3	105135987	rs13070790	C	T	rs13070790	20694013	5.00E-08	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
3	117200934	rs2927279	A	G	rs2927279	20694013	4.44E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
3	191412597	rs779506	G	A	rs779506	20694013	7.01E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
4	23266728	rs10938932	C	T	rs10938932	20694013	6.17E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
4	23274625	rs6835555	G	A	rs6835555	20694013	3.98E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G,A
4	23309835	rs12502492	A	C	rs12502492	20694013	5.00E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
4	23483330	rs740834	T	C	rs740834	20694013	4.82E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
4	31760859	rs11730273	G	T	rs11730273	20694013	6.88E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G,A
4	41713665	rs11728925	C	A	rs11728925	20694013	2.37E-08	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
4	78192318	rs10491463	T	C	rs10491463	20694013	1.49E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
4	149379537	rs6535611	A	G	rs6535611	20694013	9.59E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
5	55878971	rs12697148	G	T	rs12697148	20694013	8.76E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
5	117943259	rs6870913	C	T	rs6870913	20694013	9.20E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
6	7266055	rs2842362	G	T	rs2842362	20694013	4.15E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
6	7600469	rs6597271	A	G	rs6597271	20694013	9.69E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
6	7601436	rs17398289	T	C	rs17398289	20694013	9.04E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
6	40670716	rs9369226	A	G	rs9369226	20694013	9.63E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
6	58340472	rs12209098	A	C	rs12209098	20694013	5.14E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
6	72603664	rs2040055	C	T	rs2040055	20694013	3.34E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
6	105551229	rs13196925	T	G	rs13196925	20694013	2.25E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
6	131673070	rs4897509	A	G	rs4897509	20694013	8.45E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
6	131675201	rs9483254	A	G	rs9483254	20694013	5.87E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
6	137532751	rs9376268	G	A	rs9376268	20694013	4.00E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
7	29428760	rs7797836	C	T	rs7797836	20694013	5.52E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
7	29431552	rs2391757	A	G	rs2391757	20694013	4.41E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
7	127182308	rs6962882	C	T	rs6962882	20694013	6.82E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
7	127795804	rs10447854	T	C	rs10447854	20694013	1.44E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
8	13395662	rs10089628	T	C	rs10089628	20694013	6.87E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
8	39068176	rs7830326	A	G	rs7830326	20694013	2.70E-26	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
8	41623602	rs11780780	G	A	rs11780780	20694013	3.67E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
8	51337745	rs7839067	G	T	rs7839067	20694013	9.52E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
8	105641573	rs2880074	G	A	rs2880074	20694013	9.75E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
8	125561755	rs3829038	G	A	rs3829038	20694013	5.62E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
8	135030615	rs4897668	A	G	rs4897668	20694013	8.30E-26	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
8	142323189	rs7818687	T	C	rs7818687	20694013	4.41E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
8	143681457	rs11167150	A	G	rs11167150	20694013	8.70E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
9	343981	rs4741821	T	C	rs4741821	20694013	7.21E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
9	89419847	rs7048294	C	T	rs7048294	20694013	3.89E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
10	80923862	rs1749824	C	A	rs1749824	20694013	6.50E-13	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
10	85072264	rs10886114	A	G	rs10886114	20694013	9.22E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
10	113094037	rs10749071	A	G	rs10749071	20694013	1.23E-16	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
10	123913330	rs17103138	T	C	rs17103138	20694013	3.44E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
11	40135242	rs11035693	G	A	rs11035693	20694013	4.74E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
11	42649538	rs11604506	C	T	rs11604506	20694013	4.75E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
11	45181682	rs10838427	C	T	rs10838427	20694013	1.46E-10	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
11	49672943	rs10769599	G	A	rs10769599	20694013	4.10E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
11	57040720	rs1892964	C	A	rs1892964	20694013	9.71E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
11	57060562	rs12792781	T	C	rs12792781	20694013	5.30E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
11	86108112	rs10431169	T	C	rs10431169	20694013	3.03E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
11	88676854	rs655683	G	T	rs655683	20694013	2.15E-08	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
11	93921810	rs1792624	G	A	rs1792624	20694013	9.64E-266	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
11	96528019	rs1371352	A	G	rs1371352	20694013	9.63E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
13	47528545	rs2026692	T	C	rs2026692	20694013	3.63E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
13	61618853	rs9570428	C	T	rs9570428	20694013	4.52E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
13	74449179	rs9573320	A	G	rs9573320	20694013	3.93E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
13	74457689	rs9573322	C	A	rs9573322	20694013	8.73E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
13	86551371	rs9547465	C	T	rs9547465	20694013	3.95E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
13	109821211	rs4976846	T	C	rs4976846	20694013	1.72E-17	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
15	33551767	rs17817048	G	T	rs17817048	20694013	3.75E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
15	33564482	rs8035094	C	T	rs8035094	20694013	5.00E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
15	49102037	rs2899423	G	A	rs2899423	20694013	6.25E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
15	54288558	rs2616917	C	T	rs2616917	20694013	4.74E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
15	89996874	rs10162967	C	T	rs10162967	20694013	2.94E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
15	90000871	rs1020145	G	T	rs1020145	20694013	1.83E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
16	4404620	rs10974	C	T	rs10974	20694013	9.53E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
16	19331458	rs1023441	G	A	rs1023441	20694013	5.56E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
16	55844617	rs2244614	G	A	rs2244614	20694013	9.51E-07	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
17	37341235	rs2301775	A	G	rs2301775	20694013	3.08E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G,A
17	64410915	rs4790911	T	C	rs4790911	20694013	8.27E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
18	61281648	rs2168312	G	A	rs2168312	20694013	2.67E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
18	61344012	rs1011947	G	A	rs1011947	20694013	3.41E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
18	61508463	rs1243056	A	G	rs1243056	20694013	9.94E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
18	61509286	rs1243059	A	G	rs1243059	20694013	4.84E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
18	61512366	rs1243062	G	A	rs1243062	20694013	7.08E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
18	71805503	rs4556879	C	T	rs4556879	20694013	9.75E-07	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T,C
18	71811235	rs9952197	G	A	rs9952197	20694013	1.47E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G,A
18	71816278	rs3737512	G	A	rs3737512	20694013	1.11E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
18	71828924	rs17088883	C	T	rs17088883	20694013	5.48E-06	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
19	50419399	rs1299491	A	C	rs1299491	20694013	8.70E-08	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	C
20	42672411	rs6031318	G	A	rs6031318	20694013	7.35E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
20	52501962	rs4809944	A	G	rs4809944	20694013	5.51E-08	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	G
21	19719426	rs2406176	T	G	rs2406176	20694013	8.86E-12	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	T
22	17152611	rs4819849	A	G	rs4819849	20694013	1.47E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	NA
22	17310741	rs175149	A	G	rs175149	20694013	1.60E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A
22	29456699	rs9625679	A	G	rs9625679	20694013	4.61E-05	NA	NA	NA	475 UK Caucasian cases; 4,703 UK controls	UK(4703)	UK Caucasian(475)	ALL(5178)	EUR(5178)	ALL(5178)	Meningococcal disease	HPOID:0001287	Meningitis	DOID:9931	Waterhouse-Friderichsen syndrome	D008585	Meningitis, Meningococcal	EFOID:0004249	meningococcal infection	Adrenal gland hypofunction	NA	Research Support, Non-U.S. Gov't	A

Mapped by lexical matching(Total Items:0)
(Waiting for update.)

Mapped by homologous gene(Total Items:0)
(Waiting for update.)

Disease ID	1448
Disease	waterhouse-friderichsen syndrome
Case	(Waiting for update.)